Publications by authors named "Keith Watson"

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Poly(ionic liquid)s with Dicationic Pendants as Gas Separation Membranes.
Sudhir Ravula, Kathryn E O'Harra, Keith A Watson, Jason E Bara

Membranes (Basel)· February 2022

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Development of an automated assay for accelerated in vitro detection of DNA adduct-inducing and crosslinking agents.
Jelena Medan, Brad E Sleebs, Kurt Lackovic, Keith G Watson, Benny J Evison

Bioorg Med Chem Lett· March 2021

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Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.
Christoph Grohmann, Francesca Walker, Mark Devlin, Meng-Xiao Luo, Anderly C Chüeh, Keith G Watson

Cell Death Dis· March 2021

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Possibilities and priorities for IJED in times of uncertainty: A 40th anniversary analysis.
Michael Crossley, Kenneth King, Simon McGrath, Keith Watson

Int J Educ Dev· November 2020

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The Path Towards a Tailored Clinical Biosimilar Development.
Martin Schiestl, Gopinath Ranganna, Keith Watson, Byoungin Jung, Karsten Roth

BioDrugs· June 2020

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Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features.
Paul P Pumuye, Benny J Evison, Shyam K Konda, J Grant Collins, Celine Kelso, Keith Watson

Bioorg Med Chem· February 2020

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A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis.
Mark F van Delft, Stephane Chappaz, Yelena Khakham, Chinh T Bui, Marlyse A Debrincat, Keith G Watson

Nat Chem Biol· November 2019

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Mitoxantrone, More than Just Another Topoisomerase II Poison.
Benny J Evison, Brad E Sleebs, Keith G Watson, Don R Phillips, Suzanne M Cutts

Med Res Rev· March 2016

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Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.
Zhi-Fu Tao, Lisa Hasvold, Le Wang, Xilu Wang, Andrew M Petros, Keith G Watson

ACS Med Chem Lett· October 2014

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Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.
Michael F T Koehler, Philippe Bergeron, Edna F Choo, Kevin Lau, Chudi Ndubaku, Keith G Watson

ACS Med Chem Lett· June 2014

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Apicoplast acetyl Co-A carboxylase of the human malaria parasite is not targeted by cyclohexanedione herbicides.
Christopher D Goodman, Vanessa Mollard, Theola Louie, Georgina A Holloway, Keith G Watson

Int J Parasitol· April 2014

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Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL.
Brad E Sleebs, Wilhemus J A Kersten, Sanji Kulasegaram, George Nikolakopoulos, Effie Hatzis, Keith Watson

J Med Chem· July 2013

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Structure-guided design of a selective BCL-X(L) inhibitor.
Guillaume Lessene, Peter E Czabotar, Brad E Sleebs, Kerry Zobel, Kym N Lowes, Keith G Watson

Nat Chem Biol· June 2013

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Regulatory, biosafety and safety challenges for novel cells as substrates for human vaccines.
Ralf D Hess, Friedemann Weber, Keith Watson, Siegfried Schmitt

Vaccine· April 2012

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An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus.
Susanne C Feil, Stephanie Hamilton, Guy Y Krippner, Bo Lin, Angela Luttick, Keith G Watson

ACS Med Chem Lett· April 2012

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M2, a novel anthracenedione, elicits a potent DNA damage response that can be subverted through checkpoint kinase inhibition to generate mitotic catastrophe.
Benny J Evison, Mile Pastuovic, Rebecca A Bilardi, Robert A Forrest, Paul P Pumuye, Keith G Watson

Biochem Pharmacol· December 2011

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The changing landscape of careers in the chemical industry.
Keith J Watson

Nat Chem· August 2011

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New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation.
Oula C Mansour, Benny J Evison, Brad E Sleebs, Keith G Watson, Abraham Nudelman

J Med Chem· October 2010

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Dimeric cyclohexane-1,3-dione oximes inhibit wheat acetyl-CoA carboxylase and show anti-malarial activity.
Theola Louie, C Dean Goodman, Georgina A Holloway, Geoffrey I McFadden, Vanessa Mollard, Keith G Watson

Bioorg Med Chem Lett· August 2010

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Inhibitors of Leishmania GDP-mannose pyrophosphorylase identified by high-throughput screening of small-molecule chemical library.
Kurt Lackovic, John P Parisot, Nerida Sleebs, Jonathan B Baell, Laurent Debien, Keith G Watson

Antimicrob Agents Chemother· May 2010

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A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim.
Song Xiang, Matthew M Callaghan, Keith G Watson, Liang Tong

Proc Natl Acad Sci U S A· December 2009

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Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity.
Georgina A Holloway, William N Charman, Alan H Fairlamb, Reto Brun, Marcel Kaiser, Keith G Watson

Antimicrob Agents Chemother· July 2009

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Osteopathic postdoctoral training institutions: a decentralized model for facilitating accreditation and program quality.
Don N Peska, Michael I Opipari, D Keith Watson

Acad Med· June 2009

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Medical education summits: building a solid foundation for the future of the osteopathic medical profession.
D Keith Watson, Karen J Nichols

J Am Osteopath Assoc· March 2008

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Synthesis and biological evaluation of analogues of the anti-tumor alkaloid naamidine A.
Nicholas Aberle, Jenny Catimel, Edouard C Nice, Keith G Watson

Bioorg Med Chem Lett· July 2007

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