Publications by authors named "Kevin FitzGerald"

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Neurofilament Light Chain as a Biomarker of Hereditary Transthyretin-Mediated Amyloidosis.
Simina Ticau, Gautham V Sridharan, Shira Tsour, William L Cantley, Amy Chan, Jason A Gilbert, David Erbe, Emre Aldinc, Mary M Reilly, David Adams

Neurology· January 2021

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Hybrid IgE-IgG1 antibodies (IgEG): a new antibody class that combines IgE and IgG functionality.
Melanie Grandits, Lais C G F Palhares, Olivia Macleod, John Devlin, Oliver E Amin, Kevin FitzGerald

MAbs· December 2025

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Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors.
Melanie Grandits, Lais C G F Palhares, Gabriel Osborn, Jitesh Chauhan, Katie Stoker, Kevin FitzGerald

J Immunother Cancer· March 2025

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An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activities.
Lais C G F Palhares, Melanie Grandits, Katie Stoker, Jitesh Chauhan, Heng Sheng Sow, Kevin FitzGerald

J Exp Clin Cancer Res· February 2025

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High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.
Yesseinia I Anglero-Rodriguez, Florian A Lempp, Megha Subramanian, James McIninch, Mark K Schlegel, Kevin Fitzgerald

Nucleic Acids Res· January 2025

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Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates.
Mikyung Yu, June Qin, Xiumin Liu, Diane Ramsden, Brian Williams, Kevin Fitzgerald

Nucleic Acids Res· June 2024

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Implementation of a Clinical Vessel Wall MR Imaging Program at an Academic Medical Center.
Jae W Song, Megan Y Frame, Rob T Sellers, Connie Klahn, Kevin Fitzgerald

AJNR Am J Neuroradiol· May 2024

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RNA interference in the era of nucleic acid therapeutics.
Vasant Jadhav, Akshay Vaishnaw, Kevin Fitzgerald, Martin A Maier

Nat Biotechnol· March 2024

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Stream hydrology and a pulse subsidy shape patterns of fish foraging.
Kevin A Fitzgerald, J Ryan Bellmore, Jason B Fellman, Matthew L H Cheng, Claire E Delbecq

J Anim Ecol· December 2023

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Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.
Se-Hyung Park, Robert N Helsley, Taghreed Fadhul, Jennifer L S Willoughby, Leila Noetzli, Kevin Fitzgerald

Metabolism· August 2023

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New Approaches for Targeting PCSK9: Small-Interfering Ribonucleic Acid and Genome Editing.
Reindert F Oostveen, Amit V Khera, Sekar Kathiresan, Erik S G Stroes, Kevin Fitzgerald

Arterioscler Thromb Vasc Biol· July 2023

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RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes.
Megha Subramanian, James McIninch, Ivan Zlatev, Mark K Schlegel, Charalambos Kaittanis, Kevin Fitzgerald

Nat Commun· April 2023

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Social Isolation Activates Dormant Mammary Tumors, and Modifies Inflammatory and Mitochondrial Metabolic Pathways in the Rat Mammary Gland.
Fabia de Oliveira Andrade, Lu Jin, Robert Clarke, Imani Wood, MaryAnn Dutton, Kevin FitzGerald

Cells· March 2023

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Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis.
Francois Moreau, Bruna Brasil Brunao, Xiang-Yu Liu, Frederic Tremblay, Kevin Fitzgerald

J Lipid Res· February 2023

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Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes.
Heather J Bax, Jitesh Chauhan, Chara Stavraka, Aida Santaolalla, Gabriel Osborn, Kevin FitzGerald

Br J Cancer· January 2023

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Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD.
Se-Hyung Park, Robert N Helsley, Taghreed Fadhul, Jennifer L S Willoughby, Leila Noetzli, Kevin Fitzgerald

bioRxiv· January 2023

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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates.
Kirk M Brown, Jayaprakash K Nair, Maja M Janas, Yesseinia I Anglero-Rodriguez, Lan T H Dang, Kevin Fitzgerald

Nat Biotechnol· October 2022

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From bench to bedside: Improving the clinical safety of GalNAc-siRNA conjugates using seed-pairing destabilization.
Mark K Schlegel, Maja M Janas, Yongfeng Jiang, Joseph D Barry, Wendell Davis, Kevin Fitzgerald

Nucleic Acids Res· July 2022

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Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity.
Aimee M Deaton, Aditi Dubey, Lucas D Ward, Peter Dornbos, Jason Flannick, Kevin Fitzgerald

Nat Commun· July 2022

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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of -Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human.
Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Kevin Fitzgerald

Drug Metab Dispos· June 2022

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The Essentials of Multiomics.
John L Marshall, Beth N Peshkin, Takayuki Yoshino, Jakob Vowinckel, Håvard E Danielsen, Kevin T FitzGerald

Oncologist· April 2022

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Repurposing the Homing Endonuclease I-SceI for Positive Selection and Development of Gene-Editing Technologies.
Kok Zhi Lee, Michael A Mechikoff, Mrugesh Krishna Parasa, Tyler J Rankin, Paula Pandolfi, Kevin S Fitzgerald

ACS Synth Biol· January 2022

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NgAgo possesses guided DNA nicking activity.
Kok Zhi Lee, Michael A Mechikoff, Archana Kikla, Arren Liu, Paula Pandolfi, Kevin Fitzgerald

Nucleic Acids Res· September 2021

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Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry.
Margaret M Parker, Scott M Damrauer, Catherine Tcheandjieu, David Erbe, Emre Aldinc, Kevin Fitzgerald

Sci Rep· June 2021

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Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.
Paul J Schmidt, Kevin Fitzgerald, James S Butler, Mark D Fleming

Am J Hematol· February 2021

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