Publications by authors named "Lee Preusser"

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Thienopyridine ureas as dual inhibitors of the VEGF and Aurora kinase families.
Michael L Curtin, Robin R Frey, H Robin Heyman, Niru B Soni, Patrick A Marcotte, Lee C Preusser

Bioorg Med Chem Lett· May 2012

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Negative inotropic effect of a CB2 agonist A-955840 in isolated rabbit ventricular myocytes is independent of CB1 and CB2 receptors.
Zhi Su, Lee Preusser, Gilbert Diaz, Jonathon Green, Xiaoqin Liu

Curr Drug Saf· November 2011

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Cardiovascular effects of torcetrapib in conscious and pentobarbital-anesthetized dogs.
James S Polakowski, Andrew J King, Thomas J Campbell, Richard A Nelson, Lee C Preusser

J Cardiovasc Pharmacol· December 2009

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Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs.
Patricia N Banfor, Lee C Preusser, Thomas J Campbell, Kennan C Marsh, James S Polakowski

Am J Physiol Heart Circ Physiol· January 2008

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Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Zhonghua Pei, Xiaofeng Li, Thomas W von Geldern, David J Madar, Kenton Longenecker, Lee C Preusser

J Med Chem· November 2006

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Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety.
John K Lynch, Jennifer C Freeman, Andrew S Judd, Rajesh Iyengar, Mathew Mulhern, Lee C Preusser

J Med Chem· November 2006

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Screening for cardiovascular safety: a structure-activity approach for guiding lead selection of melanin concentrating hormone receptor 1 antagonists.
Philip R Kym, Andrew J Souers, Thomas J Campbell, John K Lynch, Andrew S Judd, Lee C Preusser

J Med Chem· April 2006

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Effects of intravenous ABT-870 (iron (III)-hydroxide oligosaccharide) on mean arterial pressure and heart rate in the anaesthetized beagle: comparison with other iron-containing haematinic agents.
Lee C Preusser, Ryan M Fryer, Armin Gerhardt, Yanhui Hu, Leticia Delgado-Herrera

Clin Exp Pharmacol Physiol· December 2005

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Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
Philip R Kym, Rajesh Iyengar, Andrew J Souers, John K Lynch, Andrew S Judd, Lee C Preusser

J Med Chem· September 2005

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Pharmacological characterization of the novel dihydropyridine potassium channel opener, (9R)-9-(3-iodo-4-methylphenyl)-5,9-dihydro-3H-furo[3,4-b]pyrano[4,3-e]pyridine-1,8(4H,7H)-dione (A-325100), and the regulation of cardiovascular function in conscious and anesthetized beagle dogs.
Ryan M Fryer, Pamela A Rakestraw, Lee C Preusser, Michael E Brune, William A Carroll

J Cardiovasc Pharmacol· August 2005

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ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders.
Lynne E Rueter, David J Anderson, Clark A Briggs, Diana L Donnelly-Roberts, Gary A Gintant, Lee C Preusser

CNS Drug Rev· September 2004

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(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine.
Ryan M Fryer, Lee C Preusser, Samuel V Calzadilla, Yanhui Hu, Hongyu Xu

J Cardiovasc Pharmacol· August 2004

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Hypertension induced by blockade of ET(B) receptors in conscious nonhuman primates: role of ET(A) receptors.
Glenn A Reinhart, Lee C Preusser, Sandra E Burke, Jerry L Wessale, Craig D Wegner

Am J Physiol Heart Circ Physiol· October 2002

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