Publications by authors named "Gilbert Diaz"

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Pharmacological characterization of A-960656, a histamine H₃ receptor antagonist with efficacy in animal models of osteoarthritis and neuropathic pain.
Marlon Cowart, Gin Hsieh, Lawrence A Black, Cenchen Zhan, Erica J Gomez, Gilbert Diaz

Eur J Pharmacol· June 2012

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Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers.
Xiaoqin Liu, James T Limberis, Zhi Su, Kathryn Houseman, Gilbert J Diaz

Life Sci· April 2012

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Ventricular rate adaptation: a novel, rapid, cellular-based in-vitro assay to identify proarrhythmic and torsadogenic compounds.
Jonathon R Green, Gilbert J Diaz, James T Limberis, Kathryn A Houseman, Zhi Su

J Pharmacol Toxicol Methods· February 2012

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Negative inotropic effect of a CB2 agonist A-955840 in isolated rabbit ventricular myocytes is independent of CB1 and CB2 receptors.
Zhi Su, Lee Preusser, Gilbert Diaz, Jonathon Green, Xiaoqin Liu

Curr Drug Saf· November 2011

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A novel secretagogue increases cardiac contractility by enhancement of L-type Ca2+ current.
Zhi Su, Deborah L Widomski, Xiaoqin Liu, James T Limberis, Jonathon Green, Gilbert Diaz

Biochem Pharmacol· October 2010

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In vitro studies on a class of quinoline containing histamine H3 antagonists.
Huaqing Liu, Robert J Altenbach, Gilbert J Diaz, Arlene M Manelli, Ruth L Martin

Bioorg Med Chem Lett· June 2010

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Electrophysiologic characterization of a novel hERG channel activator.
Zhi Su, James Limberis, Andrew Souers, Philip Kym, Ann Mikhail, Gilbert Diaz

Biochem Pharmacol· April 2009

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3-amino-benzo[d]isoxazoles as novel multitargeted inhibitors of receptor tyrosine kinases.
Zhiqin Ji, Asma A Ahmed, Daniel H Albert, Jennifer J Bouska, Peter F Bousquet, Gilbert Diaz

J Med Chem· March 2008

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Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor.
Gang Zhao, Andrew J Souers, Martin Voorbach, H Doug Falls, Brian Droz, Gilbert J Diaz

J Med Chem· February 2008

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1,4-Dihydroindeno[1,2-c]pyrazoles with acetylenic side chains as novel and potent multitargeted receptor tyrosine kinase inhibitors with low affinity for the hERG ion channel.
Jürgen Dinges, Daniel H Albert, Lee D Arnold, Kimba L Ashworth, Irini Akritopoulou-Zanze, Gilbert J Diaz

J Med Chem· May 2007

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Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity.
Andrew S Judd, Andrew J Souers, Dariusz Wodka, Gang Zhao, Mathew M Mulhern, Gilbert Diaz

Bioorg Med Chem Lett· April 2007

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Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
Marlon Cowart, Gregory A Gfesser, Kaitlin E Browman, Ramin Faghih, Thomas R Miller, Gilbert J Diaz

Biochem Pharmacol· April 2007

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Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: the effects of chirality on substituted indan-1-ylamines.
Andrew J Souers, Rajesh R Iyengar, Andrew S Judd, David W A Beno, Ju Gao, Gilbert J Diaz

Bioorg Med Chem Lett· February 2007

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An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists.
Rajesh R Iyengar, John K Lynch, Mathew M Mulhern, Andrew S Judd, Jennifer C Freeman, Gilbert Diaz

Bioorg Med Chem Lett· February 2007

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Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety.
John K Lynch, Jennifer C Freeman, Andrew S Judd, Rajesh Iyengar, Mathew Mulhern, Gilbert Diaz

J Med Chem· November 2006

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The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o.
Gilbert J Diaz, Katina Daniell, Sandra T Leitza, Ruth L Martin, Zhi Su

J Pharmacol Toxicol Methods· March 2005

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Nonpeptide luteinizing hormone-releasing hormone antagonists derived from erythromycin A: design, synthesis, and biological activity of cladinose replacement analogues.
John T Randolph, Philip Waid, Charles Nichols, Daryl Sauer, Fortuna Haviv, Gilbert Diaz

J Med Chem· February 2004

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Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats.
Nathan L Lubbers, James S Polakowski, Craig D Wegner, Sandra E Burke, Gilbert J Diaz

Eur J Pharmacol· January 2002

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