Publications by authors named "Lester I Binder"

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Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease.
Chelsea T Tiernan, Stephen D Ginsberg, Angela L Guillozet-Bongaarts, Sarah M Ward, Bin He, Lester I Binder

Neurobiol Aging· June 2016

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Tau oligomers as potential targets for early diagnosis of tauopathy.
Naruhiko Sahara, Yan Ren, Sarah Ward, Lester I Binder, Tetsuya Suhara

J Alzheimers Dis· January 2015

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TOC1: a valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy.
Sarah M Ward, Diana S Himmelstein, Yan Ren, Yifan Fu, Xiao-Wen Yu, Lester I Binder

Neurobiol Dis· July 2014

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TOC1: characterization of a selective oligomeric tau antibody.
Sarah M Ward, Diana S Himmelstein, Jody K Lancia, Yifan Fu, Kristina R Patterson, Lester I Binder

J Alzheimers Dis· June 2014

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Alterations in the nuclear architecture produced by the overexpression of tau protein in neuroblastoma cells.
Hugo C Monroy-Ramírez, Gustavo Basurto-Islas, Raul Mena, Bulmaro Cisneros, Lester I Binder

J Alzheimers Dis· February 2014

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Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.
Jose J Jarero-Basulto, Jose Luna-Muñoz, Raul Mena, Zdena Kristofikova, Daniela Ripova, Lester I Binder

J Neuropathol Exp Neurol· December 2013

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Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.
Nicholas M Kanaan, Gustavo F Pigino, Scott T Brady, Orly Lazarov, Lester I Binder

Exp Neurol· August 2013

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Tau as a therapeutic target in neurodegenerative disease.
Diana S Himmelstein, Sarah M Ward, Jody K Lancia, Kristina R Patterson, Lester I Binder

Pharmacol Ther· October 2012

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Tau oligomers and tau toxicity in neurodegenerative disease.
Sarah M Ward, Diana S Himmelstein, Jody K Lancia, Lester I Binder

Biochem Soc Trans· August 2012

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Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.
Nicholas M Kanaan, Gerardo Morfini, Gustavo Pigino, Nichole E LaPointe, Athena Andreadis, Lester I Binder

Neurobiol Aging· April 2012

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Ubiquitin is associated with early truncation of tau protein at aspartic acid(421) during the maturation of neurofibrillary tangles in Alzheimer's disease.
Francisco García-Sierra, Jose J Jarero-Basulto, Zdena Kristofikova, Emerich Majer, Lester I Binder

Brain Pathol· March 2012

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Selective tau tyrosine nitration in non-AD tauopathies.
Juan F Reyes, Changiz Geula, Laurel Vana, Lester I Binder

Acta Neuropathol· January 2012

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Hsp70 alters tau function and aggregation in an isoform specific manner.
Kellen Voss, Benjamin Combs, Kristina R Patterson, Lester I Binder, T Chris Gamblin

Biochemistry· January 2012

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Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Laurel Vana, Nicholas M Kanaan, Isabella C Ugwu, Joanne Wuu, Elliott J Mufson, Lester I Binder

Am J Pathol· November 2011

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Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.
Kristina R Patterson, Sarah M Ward, Benjamin Combs, Kellen Voss, Nicholas M Kanaan, Lester I Binder

Biochemistry· November 2011

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X-ray diffraction from intact tau aggregates in human brain tissue.
Eric C Landahl, Olga Antipova, Angela Bongaarts, Raul Barrea, Robert Berry, Lester I Binder

Nucl Instrum Methods Phys Res A· September 2011

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In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice.
Kaoru Yamada, John R Cirrito, Floy R Stewart, Hong Jiang, Mary Beth Finn, Lester I Binder

J Neurosci· September 2011

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Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.
Kristina R Patterson, Christine Remmers, Yifan Fu, Sarah Brooker, Nicholas M Kanaan, Lester I Binder

J Biol Chem· July 2011

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Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases.
Nicholas M Kanaan, Gerardo A Morfini, Nichole E LaPointe, Gustavo F Pigino, Kristina R Patterson, Lester I Binder

J Neurosci· July 2011

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Tyrosine nitration within the proline-rich region of Tau in Alzheimer's disease.
Juan F Reyes, Yifan Fu, Laurel Vana, Nicholas M Kanaan, Lester I Binder

Am J Pathol· May 2011

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Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.
Laurel Vana, Nicholas M Kanaan, Kevin Hakala, Susan T Weintraub, Lester I Binder

Biochemistry· February 2011

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Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro.
Nichole E Lapointe, Peleg M Horowitz, Angela L Guillozet-Bongaarts, Andres Silva, Athena Andreadis, Lester I Binder

Biochemistry· December 2009

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Axonal transport defects in neurodegenerative diseases.
Gerardo A Morfini, Matthew Burns, Lester I Binder, Nicholas M Kanaan, Nichole LaPointe

J Neurosci· October 2009

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The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.
Nichole E LaPointe, Gerardo Morfini, Gustavo Pigino, Irina N Gaisina, Alan P Kozikowski, Lester I Binder

J Neurosci Res· February 2009

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Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy.
Chad Dickey, Clara Kraft, Umesh Jinwal, John Koren, Amelia Johnson, Lester I Binder

Am J Pathol· January 2009

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