Publications by authors named "Linzhao Cheng"

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Efficient high-precision transgene knock-in by Recombinases (Redα/β)-enhanced DNA integration-CRISPR-Cas9 (RED-CRISPR).
Wenqing Li, Senquan Liu, Xiaoyu Fang, Jiaqi Zou, Qin Jiang, Linzhao Cheng, Chengkun Wang

Nat Commun· December 2025

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Enhanced engraftment of human haematopoietic stem cells via mechanical remodelling mediated by the corticotropin-releasing hormone.
Mingming Wu, Haoxiang Yang, Senquan Liu, Lai Jiang, Tingting Liang, Cheng-Kui Qu, Linzhao Cheng

Nat Biomed Eng· May 2025

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Engineered extracellular vesicles enable high-efficient delivery of intracellular therapeutic proteins.
Ding Ma, An Xie, Jiahui Lv, Xiaolin Min, Xinye Zhang, Linzhao Cheng

Protein Cell· October 2024

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An Optimized Human Erythroblast Differentiation System Reveals Cholesterol-Dependency of Robust Production of Cultured Red Blood Cells Ex Vivo.
Enyu Wang, Senquan Liu, Xinye Zhang, Qingyou Peng, Huijuan Yu, Linzhao Cheng

Adv Sci (Weinh)· June 2024

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Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
Lei Gao, Yongping Sun, Xinye Zhang, Ding Ma, An Xie, Linzhao Cheng

Adv Sci (Weinh)· June 2023

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PEAR1 is a potential regulator of early hematopoiesis of human pluripotent stem cells.
Shuo Zhang, Kengyuan Qu, Shuzhen Lyu, Dixie L Hoyle, Cory Smith, Linzhao Cheng, Tao Cheng

J Cell Physiol· January 2023

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Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution.
Bin Li, Wen Zhang, Chuang Guo, Hao Xu, Longfei Li, Linzhao Cheng

Nat Methods· June 2022

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Erythropoietic properties of human induced pluripotent stem cells-derived red blood cells in immunodeficient mice.
Jiusheng Deng, Moira Lancelot, Ryan Jajosky, Qiaomei Deng, Kristin Deeb, Linzhao Cheng

Am J Hematol· February 2022

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In memory of Hal E. Broxmeyer, a pluripotent scientist, pioneer, and mentor.
Linzhao Cheng, Bin Guo, Xinxin Huang, Tao Cheng

Blood Sci· January 2022

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Gene and protein expression in human megakaryocytes derived from induced pluripotent stem cells.
Kai Kammers, Margaret A Taub, Rasika A Mathias, Lisa R Yanek, Kanika Kanchan, Linzhao Cheng

J Thromb Haemost· July 2021

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BMI1 enables extensive expansion of functional erythroblasts from human peripheral blood mononuclear cells.
Senquan Liu, Mengyao Wu, Moira Lancelot, Jiusheng Deng, Yongxing Gao, Linzhao Cheng

Mol Ther· May 2021

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Sequential cellular niches control the generation of enucleated erythrocytes from human pluripotent stem cells.
Jun Shen, Yaoyao Zhu, Cuicui Lyu, Zicen Feng, Shuzhen Lyu, Linzhao Cheng, Tao Cheng

Haematologica· April 2021

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gain-of-function mutation modulates the stiffness of smooth muscle cells and compromises vascular mechanics.
Xin Yi Chan, Eugenia Volkova, Joon Eoh, Rebecca Black, Lilly Fang, Linzhao Cheng

iScience· April 2021

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Decline of SARS-CoV-2-specific IgG, IgM and IgA in convalescent COVID-19 patients within 100 days after hospital discharge.
Huan Ma, Dan Zhao, Weihong Zeng, Yunru Yang, Xiaowen Hu, Linzhao Cheng

Sci China Life Sci· March 2021

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Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole-genome and RNA sequencing.
Kai Kammers, Margaret A Taub, Benjamin Rodriguez, Lisa R Yanek, Ingo Ruczinski, Linzhao Cheng

Blood· February 2021

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Highly efficient magnetic labelling allows MRI tracking of the homing of stem cell-derived extracellular vesicles following systemic delivery.
Zheng Han, Senquan Liu, Yigang Pei, Zheng Ding, Yuguo Li, Linzhao Cheng

J Extracell Vesicles· January 2021

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Generation and characterization of a novel human iPSC line from a resilient Alzheimer's disease patient.
Debamitra Das, Jiaxin Li, Senquan Liu, Esther Oh, Linzhao Cheng

Stem Cell Res· October 2020

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iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu.
Itzy E Morales Pantoja, Matthew D Smith, Labchan Rajbhandari, Linzhao Cheng, Yongxing Gao

PLoS One· August 2020

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Human Forebrain Organoids from Induced Pluripotent Stem Cells: A Novel Approach to Model Repair of Ionizing Radiation-Induced DNA Damage in Human Neurons.
Debamitra Das, Jiaxin Li, Linzhao Cheng, Sonia Franco, Vasiliki Mahairaki

Radiat Res· August 2020

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Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program.
Kanika Kanchan, Kruthika Iyer, Lisa R Yanek, Ivan Carcamo-Orive, Margaret A Taub, Linzhao Cheng

Stem Cell Res· July 2020

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Serum IgA, IgM, and IgG responses in COVID-19.
Huan Ma, Weihong Zeng, Hongliang He, Dan Zhao, Dehua Jiang, Linzhao Cheng

Cell Mol Immunol· July 2020

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Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors.
In Young Choi, Hotae Lim, Hyeon Jin Cho, Yohan Oh, Bin-Kuan Chou, Linzhao Cheng

Elife· February 2020

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The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model.
Moriah E Katt, Lakyn N Mayo, Shannon E Ellis, Vasiliki Mahairaki, Jeffrey D Rothstein, Linzhao Cheng

Fluids Barriers CNS· July 2019

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Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells.
Senquan Liu, Vasiliki Mahairaki, Hao Bai, Zheng Ding, Jiaxin Li, Linzhao Cheng

Stem Cells· June 2019

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Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior.
Raleigh M Linville, Jackson G DeStefano, Matt B Sklar, Zinnia Xu, Alanna M Farrell, Chengyan Chu, Linzhao Cheng

Biomaterials· January 2019

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