Publications by authors named "Lisa Marroquin"

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Discovery of Atirmociclib (PF-07220060): A Potent and Selective CDK4 Inhibitor.
Gary M Gallego, Cynthia Palmer, Suvi Orr, Louise Bernier, Ping Chen, Lisa Marroquin

J Med Chem· December 2025

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An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury.
Shingo Oda, Yuka Uchida, Michael D Aleo, Petra H Koza-Taylor, Yusuke Matsui, Lisa D Marroquin

Arch Toxicol· January 2021

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Transporter-Mediated Disposition, Clinical Pharmacokinetics and Cholestatic Potential of Glyburide and Its Primary Active Metabolites.
Rui Li, Yi-An Bi, Anna Vildhede, Renato J Scialis, Sumathy Mathialagan, Lisa D Marroquin

Drug Metab Dispos· July 2017

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Assessment of Bile Salt Export Pump (BSEP) Inhibition in Membrane Vesicles Using Radioactive and LC/MS-Based Detection Methods.
Lisa D Marroquin, Paul D Bonin, Julie Keefer, Thomas Schroeter

Curr Protoc Toxicol· February 2017

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Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis.
Kimberly Lapham, Jonathan Novak, Lisa D Marroquin, Rachel Swiss, Shuzhen Qin

Chem Res Toxicol· October 2016

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Identifying Compounds that Induce Opening of the Mitochondrial Permeability Transition Pore in Isolated Rat Liver Mitochondria.
Lisa Marroquin, Rachel Swiss, Yvonne Will

Curr Protoc Toxicol· May 2014

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Epithelial tissue hyperplasia induced by the RAF inhibitor PF-04880594 is attenuated by a clinically well-tolerated dose of the MEK inhibitor PD-0325901.
Vince R Torti, Donald Wojciechowicz, Wenyue Hu, Annette John-Baptiste, Winston Evering, Lisa D Marroquin

Mol Cancer Ther· October 2012

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Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase.
Wenyue Hu, Shuyan Lu, Indrawan McAlpine, Joseph D Jamieson, Dong U Lee, Lisa D Marroquin

Toxicol Sci· September 2012

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PD0325901, a mitogen-activated protein kinase kinase inhibitor, produces ocular toxicity in a rabbit animal model of retinal vein occlusion.
Wenhu Huang, Amy H Yang, Diane Matsumoto, Walter Collette, Lisa Marroquin

J Ocul Pharmacol Ther· December 2009

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Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro.
James A Dykens, Joseph Jamieson, Lisa Marroquin, Sashi Nadanaciva, Puja A Billis

Toxicol Appl Pharmacol· December 2008

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Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells.
Yvonne Will, James A Dykens, Sashi Nadanaciva, Brad Hirakawa, Joseph Jamieson, Lisa D Marroquin

Toxicol Sci· November 2008

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In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone.
James A Dykens, Joseph D Jamieson, Lisa D Marroquin, Sashi Nadanaciva, Jinghai J Xu

Toxicol Sci· June 2008

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Circumventing the Crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants.
Lisa D Marroquin, James Hynes, James A Dykens, Joseph D Jamieson, Yvonne Will

Toxicol Sci· June 2007

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Strategies to reduce late-stage drug attrition due to mitochondrial toxicity.
James A Dykens, Lisa D Marroquin, Yvonne Will

Expert Rev Mol Diagn· March 2007

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Investigation of drug-induced mitochondrial toxicity using fluorescence-based oxygen-sensitive probes.
James Hynes, Lisa D Marroquin, Vladimir I Ogurtsov, Katerina N Christiansen, Gregory J Stevens

Toxicol Sci· July 2006

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Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions.
Joel S Griffitts, Danielle L Huffman, Johanna L Whitacre, Brad D Barrows, Lisa D Marroquin

J Biol Chem· November 2003

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