Publications by authors named "Markus Kohlmann"

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Combined TNF-α and OX40L targeting as a new treatment option for hidradenitis suppurativa.
Thomas Leeuw, Deimantė Šimaitė, Karen Heyninck, Clement Levin, Sigrid Cornelis, Markus Kohlmann

J Allergy Clin Immunol Glob· August 2025

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Deciphering differential biomarkers for anti-interleukin-6 receptor and anti-tumour necrosis factor-α treatment response in rheumatoid arthritis by multiomics analysis.
Inoncent Agueusop, Daniel Margerie, Anne Remaury, Raphaël Brard, Francesca Frau, Markus Kohlmann

RMD Open· August 2025

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First-in-Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants.
Nassr Nassr, Faiza Rharbaoui, Dietmar Weitz, Johann Gassenhuber, Markus Rehberg, Markus Kohlmann

Clin Pharmacol Ther· July 2025

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Corrigendum: An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Alexander Vugler, James O'connell, Mai Anh Nguyen, Dietmar Weitz, Thomas Leeuw, Markus Kohlmann

Front Pharmacol· October 2024

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Additive efficacy of a bispecific anti-TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis.
Nadine Biesemann, Daniel Margerie, Christian Asbrand, Markus Rehberg, Virginia Savova, Markus Kohlmann

Sci Transl Med· February 2023

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An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.
Alexander Vugler, James O'Connell, Mai Anh Nguyen, Dietmar Weitz, Thomas Leeuw, Markus Kohlmann

Front Pharmacol· November 2022

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Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites.
Timothy Ackerson, Alexander Amberg, Jens Atzrodt, Catherine Arabeyre, Elisabeth Defossa, Markus Kohlmann

J Biochem Mol Toxicol· August 2019

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Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity.
Jiedong Qiu, Sibylle J Hauske, Shiqi Zhang, Angelica Rodriguez-Niño, Thomas Albrecht, Markus Kohlmann

Amino Acids· January 2019

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Sulfamide as Zinc Binding Motif in Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa).
Nis Halland, Jörg Czech, Werngard Czechtizky, Andreas Evers, Markus Follmann, Markus Kohlmann

J Med Chem· October 2016

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visualization of osteoarthritic hypertrophic lesions.
Hai-Yu Hu, Ngee-Han Lim, Hans-Paul Juretschke, Danping Ding-Pfennigdorff, Peter Florian, Markus Kohlmann

Chem Sci· November 2015

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Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa) from Natural Product Anabaenopeptin.
Nis Halland, Mark Brönstrup, Jörg Czech, Werngard Czechtizky, Andreas Evers, Markus Kohlmann

J Med Chem· June 2015

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Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins.
Angela Kling, Peer Lukat, Deepak V Almeida, Armin Bauer, Evelyne Fontaine, Markus Kohlmann

Science· June 2015

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End-organ protection in hypertension by the novel and selective Rho-kinase inhibitor, SAR407899.
Matthias Löhn, Oliver Plettenburg, Aimo Kannt, Markus Kohlmann, Armin Hofmeister

World J Cardiol· January 2015

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Small Macrocycles As Highly Active Integrin α2β1 Antagonists.
Nis Halland, Horst Blum, Christian Buning, Markus Kohlmann, Andreas Lindenschmidt

ACS Med Chem Lett· February 2014

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Discovery and pharmacological characterization of SAR707 as novel and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD1).
Marc D Voss, Gerhard Zoller, Hans Matter, Andreas W Herling, Gabriele Biemer-Daub, Markus Kohlmann

Eur J Pharmacol· May 2013

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Benzimidazole-carboxamides as potent and bioavailable stearoyl-CoA desaturase (SCD1) inhibitors from ligand-based virtual screening and chemical optimization.
Hans Matter, Gerhard Zoller, Andreas W Herling, Juan-Antonio Sanchez-Arias, Christophe Philippo, Markus Kohlmann

Bioorg Med Chem Lett· March 2013

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Identification of high-affinity P2Y₁₂ antagonists based on a phenylpyrazole glutamic acid piperazine backbone.
Gernot Zech, Gerhard Hessler, Andreas Evers, Tilo Weiss, Peter Florian, Markus Kohlmann

J Med Chem· October 2012

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Novel β-amino acid derivatives as inhibitors of cathepsin A.
Sven Ruf, Christian Buning, Herman Schreuder, Georg Horstick, Wolfgang Linz, Markus Kohlmann

J Med Chem· September 2012

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Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor.
Matthias Löhn, Oliver Plettenburg, Yuri Ivashchenko, Aimo Kannt, Armin Hofmeister, Markus Kohlmann

Hypertension· September 2009

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Differential epitope identification of antibodies against intracellular domains of alzheimer's amyloid precursor protein using high resolution affinity-mass spectrometry.
Xiaodan Tian, Madalina Maftei, Markus Kohlmann, Bernadette Allinquant, Michael Przybylski

Subcell Biochem· January 2008

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Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometry.
Xiaodan Tian, Roxana Cecal, JoAnne McLaurin, Marilena Manea, Raluca Stefanescu, Markus Kohlmann

Eur J Mass Spectrom (Chichester)· January 2006

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"Affinity-proteomics": direct protein identification from biological material using mass spectrometric epitope mapping.
Marcus Macht, Andreas Marquardt, Sören-Oliver Deininger, Eugen Damoc, Markus Kohlmann

Anal Bioanal Chem· February 2004

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