Publications by authors named "Matthew Bogdanffy"

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Mode of action and human relevance assessment of male CD-1 mouse renal adenocarcinoma associated with lifetime exposure to empagliflozin.
Jonathan A Phillips, Mitchell E Taub, Matthew S Bogdanffy, Jing Yuan, Brian Knight

J Appl Toxicol· October 2022

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Tg.rasH2 Mouse Model for Assessing Carcinogenic Potential of Pharmaceuticals: Industry Survey of Current Practices.
Matthew S Bogdanffy, Jacob Lesniak, Raja Mangipudy, Frank D Sistare, Karyn Colman

Int J Toxicol· March 2021

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Identification of novel azaindazole CCR1 antagonist clinical candidates.
Christian Harcken, Daniel Kuzmich, Brain Cook, Can Mao, Darren Disalvo, Matthew Bogdanffy

Bioorg Med Chem Lett· February 2019

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An Industry Perspective on the 2017 EMA Guideline on First-in-Human and Early Clinical Trials.
Joseph DeGeorge, Sarah Robertson, Lynne Butler, Mazin Derzi, S Aubrey Stoch, Matthew Bogdanffy

Clin Pharmacol Ther· April 2018

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Current nonclinical testing paradigms in support of safe clinical trials: An IQ Consortium DruSafe perspective.
Lynne D Butler, Peggy Guzzie-Peck, James Hartke, Matthew S Bogdanffy, Yvonne Will

Regul Toxicol Pharmacol· July 2017

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Nonclinical safety of the sodium-glucose cotransporter 2 inhibitor empagliflozin.
Matthew S Bogdanffy, Robert F Stachlewitz, Susan van Tongeren, Brian Knight, Dale E Sharp

Int J Toxicol· September 2015

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Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat.
Mark R Fielden, Alex Nie, Michael McMillian, Chandi S Elangbam, Bruce A Trela, Matthew Bogdanffy

Toxicol Sci· May 2008

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A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry.
Justin G Teeguarden, Matthew S Bogdanffy, Tammie R Covington, Cecilia Tan, Annie M Jarabek

Inhal Toxicol· February 2008

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Evaluation of effects from repeated inhalation exposure of F344 rats to high concentrations of propylene.
Lynn H Pottenger, Linda A Malley, Matthew S Bogdanffy, E Maria Donner, Patricia B Upton

Toxicol Sci· June 2007

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Vinyl acetate induces intracellular acidification in mouse oral buccal epithelial cells.
Tetsuji Nakamoto, Mark Wagner, James E Melvin, Matthew S Bogdanffy

Toxicol Lett· August 2005

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Dose-dependent transitions in mechanisms of toxicity.
William Slikker, Melvin E Andersen, Matthew S Bogdanffy, James S Bus, Steven D Cohen

Toxicol Appl Pharmacol· December 2004

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Dose-dependent transitions in mechanisms of toxicity: case studies.
William Slikker, Melvin E Andersen, Matthew S Bogdanffy, James S Bus, Steven D Cohen

Toxicol Appl Pharmacol· December 2004

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DNA methylation, cell proliferation, and histopathology in rats following repeated inhalation exposure to dimethyl sulfate.
Brian H Mathison, S Randall Frame, Matthew S Bogdanffy

Inhal Toxicol· August 2004

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Interspecies dose extrapolation for inhaled dimethyl sulfate: a PBPK model-based analysis using nasal cavity N7-methylguanine adducts.
Ramesh Sarangapani, Justin G Teeguarden, P Robinan Gentry, Harvey J Clewell, Hugh A Barton, Matthew S Bogdanffy

Inhal Toxicol· August 2004

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Response to Umeda et al.
Matthew Bogdanffy, Rudolph Valentine, Dawn Goodman, Thomas Starr

J Occup Health· May 2004

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Vinyl acetate decreases intracellular pH in rat nasal epithelial cells.
R Clark Lantz, Jason Orozco, Matthew S Bogdanffy

Toxicol Sci· October 2003

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Workshop overview: use of genomic data in risk assessment.
Michael L Cunningham, Matthew S Bogdanffy, Timothy R Zacharewski, Ronald N Hines

Toxicol Sci· June 2003

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Differentiating between local cytotoxicity, mitogenesis, and genotoxicity in carcinogen risk assessments: the case of vinyl acetate.
Matthew S Bogdanffy, Rudolph Valentine

Toxicol Lett· April 2003

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Physiologically-based kinetic modeling of vapours toxic to the respiratory tract.
Matthew S Bogdanffy, Ramesh Sarangapani

Toxicol Lett· February 2003

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Histochemical localisation of carboxylesterase activity in rat and mouse oral cavity mucosa.
Darren A Robinson, Matthew S Bogdanffy, Celia J Reed

Toxicology· December 2002

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Physiologically based pharmacokinetic (PBPK) models for nasal tissue dosimetry of organic esters: assessing the state-of-knowledge and risk assessment applications with methyl methacrylate and vinyl acetate.
Melvin E Andersen, Trevor Green, Clay B Frederick, Matthew S Bogdanffy

Regul Toxicol Pharmacol· December 2002

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Vinyl acetate-induced intracellular acidification: implications for risk assessment.
Matthew S Bogdanffy

Toxicol Sci· April 2002

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Plasma pharmacokinetics and tissue distribution of a N-pyrrolo-[1,2-c]imidazolylphenyl sulfonamide in rats.
Mehran F Moghaddam, Matthew S Bogdanffy, Alethia Brown, Kim Ford, Lamaat Shalaby

Drug Metab Dispos· January 2002

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