Publications by authors named "Matthew D Lloyd"

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Correction: Molecular basis of acyl-CoA ester recognition by α-methylacyl-CoA racemase from Mycobacterium tuberculosis.
Otsile O Mojanaga, Timothy J Woodman, Matthew D Lloyd, K Ravi Acharya

J Biol Chem· November 2025

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Structural basis for inhibition of Mycobacterium tuberculosis α-methylacyl-CoA racemase by 2-arylthiopropanoyl-CoA inhibitor analogs.
Otsile O Mojanaga, Timothy J Woodman, Matthew D Lloyd, K Ravi Acharya

J Biol Chem· October 2025

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Molecular basis of acyl-CoA ester recognition by α-methylacyl-CoA racemase from Mycobacterium tuberculosis.
Otsile O Mojanaga, Timothy J Woodman, Matthew D Lloyd, K Ravi Acharya

J Biol Chem· July 2025

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Quantitation and Error Measurements in Dose-Response Curves.
Bharath Srinivasan, Matthew D Lloyd

J Med Chem· February 2025

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Dose-Response Curves and the Determination of IC and EC Values.
Bharath Srinivasan, Matthew D Lloyd

J Med Chem· October 2024

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Functional implications of unusual NOS and SONOS covalent linkages found in proteins.
Matthew D Lloyd, Kyle S Gregory, K Ravi Acharya

Chem Commun (Camb)· August 2024

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α-Methylacyl-CoA Racemase from -Detailed Kinetic and Structural Characterization of the Active Site.
Otsile O Mojanaga, Timothy J Woodman, Matthew D Lloyd, K Ravi Acharya

Biomolecules· March 2024

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Recombinant protein production for structural and kinetic studies: A case study using M. tuberculosis α-methylacyl-CoA racemase (MCR).
Otsile O Mojanaga, K Ravi Acharya, Matthew D Lloyd

Methods Enzymol· October 2023

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Analysis of enzyme reactions using NMR techniques: A case study with α-methylacyl-CoA racemase (AMACR).
Timothy J Woodman, Matthew D Lloyd

Methods Enzymol· October 2023

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Steady-state kinetic analysis of reversible enzyme inhibitors: A case study on calf intestine alkaline phosphatase.
Henry Brooke, Meghna Ghoshray, Archad Ibrahim, Matthew D Lloyd

Methods Enzymol· October 2023

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Limits of Solid Solution and Evolution of Crystal Morphology in (LaRE)FeO Perovskites by Low Temperature Hydrothermal Crystallization.
Lu Jia, Matthew D Lloyd, Martin R Lees, Limin Huang, Richard I Walton

Inorg Chem· March 2023

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Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity Interruption of Redox Environment.
Jing Li, Ping Cheng, Shoufeng Li, Pengfei Zhao, Bing Han, Matthew D Lloyd

Antioxid Redox Signal· June 2021

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Racemases and epimerases operating through a 1,1-proton transfer mechanism: reactivity, mechanism and inhibition.
Matthew D Lloyd, Maksims Yevglevskis, Amit Nathubhai, Tony D James, Michael D Threadgill

Chem Soc Rev· May 2021

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UVA-Triggered Drug Release and Photo-Protection of Skin.
Vega Widya Karisma, Wei Wu, Mingxing Lei, Huawen Liu, Muhammad Farrukh Nisar, Matthew D Lloyd

Front Cell Dev Biol· February 2021

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High-Throughput Screening for the Discovery of Enzyme Inhibitors.
Matthew D Lloyd

J Med Chem· October 2020

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Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents.
Maksims Yevglevskis, Amit Nathubhai, Katty Wadda, Guat L Lee, Suzanne Al-Rawi, Matthew D Lloyd

Bioorg Chem· November 2019

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Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships.
Yoana D Petrova, Katty Wadda, Amit Nathubhai, Maksims Yevglevskis, Paul J Mitchell, Matthew D Lloyd

Bioorg Chem· November 2019

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Structure-activity relationships of rationally designed AMACR 1A inhibitors.
Maksims Yevglevskis, Guat L Lee, Amit Nathubhai, Yoana D Petrova, Tony D James, Matthew D Lloyd

Bioorg Chem· September 2018

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Long-wavelength TCF-based fluorescence probes for the detection and intracellular imaging of biological thiols.
Adam C Sedgwick, Jordan E Gardiner, Gyoungmi Kim, Maksims Yevglevskis, Matthew D Lloyd

Chem Commun (Camb)· May 2018

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A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate.
Maksims Yevglevskis, Guat L Lee, Amit Nathubhai, Yoana D Petrova, Tony D James, Matthew D Lloyd

Chem Commun (Camb)· May 2017

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Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.
Amit Nathubhai, Teemu Haikarainen, Jarkko Koivunen, Sudarshan Murthy, Françoise Koumanov, Matthew D Lloyd

J Med Chem· January 2017

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Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases.
Amit Nathubhai, Teemu Haikarainen, Penelope C Hayward, Silvia Muñoz-Descalzo, Andrew S Thompson, Matthew D Lloyd

Eur J Med Chem· August 2016

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The different catalytic roles of the metal-binding ligands in human 4-hydroxyphenylpyruvate dioxygenase.
Chih-Wei Huang, Hsiu-Chen Liu, Chia-Pei Shen, Yi-Tong Chen, Sung-Jai Lee, Matthew D Lloyd

Biochem J· May 2016

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A study on the AMACR catalysed elimination reaction and its application to inhibitor testing.
Maksims Yevglevskis, Guat L Lee, Jenny Sun, Shiyi Zhou, Xiaolong Sun, Matthew D Lloyd

Org Biomol Chem· January 2016

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Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro.
Helen A Paine, Amit Nathubhai, Esther C Y Woon, Peter T Sunderland, Pauline J Wood, Matthew D Lloyd

Bioorg Med Chem· September 2015

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