Publications by authors named "Matthias Gabler"

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Allosteric modulation of the farnesoid X receptor by a small molecule.
Matthias Gabler, Jan Kramer, Jurema Schmidt, Julius Pollinger, Julia Weber

Sci Rep· May 2018

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Nonacidic Farnesoid X Receptor Modulators.
Daniel Flesch, Sun-Yee Cheung, Jurema Schmidt, Matthias Gabler, Pascal Heitel

J Med Chem· August 2017

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SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound.
Christina Lamers, Daniel Merk, Matthias Gabler, Daniel Flesch, Astrid Kaiser

Future Med Chem· September 2016

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Fragmentation of GW4064 led to a highly potent partial farnesoid X receptor agonist with improved drug-like properties.
Daniel Flesch, Matthias Gabler, Andreas Lill, Roberto Carrasco Gomez, Ramona Steri

Bioorg Med Chem· July 2015

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Anthranilic acid derivatives as nuclear receptor modulators--development of novel PPAR selective and dual PPAR/FXR ligands.
Daniel Merk, Christina Lamers, Julia Weber, Daniel Flesch, Matthias Gabler

Bioorg Med Chem· February 2015

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Revealing the macromolecular targets of complex natural products.
Daniel Reker, Anna M Perna, Tiago Rodrigues, Petra Schneider, Michael Reutlinger, Matthias Gabler

Nat Chem· December 2014

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Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR).
Daniel Merk, Matthias Gabler, Roberto Carrasco Gomez, Daniel Flesch, Thomas Hanke

Bioorg Med Chem· April 2014

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[Mechanism of action of paracetamol--further contribution to discovery].
Matthias Gabler, Manfred Schubert-Zsilavecz

Pharm Unserer Zeit· July 2012

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Tertiary alkylamines as nucleophiles in substitution reactions at heteroaromatic halide during the synthesis of the highly potent pirinixic acid derivative 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS-121).
Matthias Gabler, Manfred Schubert-Zsilavecz

Molecules· December 2011

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