Publications by authors named "Julius Pollinger"

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Advancing regulatory dialogue: In silico models for improved vaccine biomanufacturing - an expert meeting report.
Irina Meln, Wim Van Molle, Mónica Perea Vélez, Greger Abrahamsen, Koen Brusselmans, Julius Carl Pollinger

Vaccine· May 2025

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Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties.
Max Lewandowski, Melania Carmina, Loris Knümann, Minh Sai, Sabine Willems, Julius Pollinger

J Med Chem· February 2024

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Targeting the Alternative Vitamin E Metabolite Binding Site Enables Noncanonical PPARγ Modulation.
Silvia Arifi, Julian A Marschner, Julius Pollinger, Laura Isigkeit, Pascal Heitel

J Am Chem Soc· July 2023

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Systematic Assessment of Fragment Identification for Multitarget Drug Design.
Steffen Brunst, Jan S Kramer, Whitney Kilu, Jan Heering, Julius Pollinger

ChemMedChem· April 2021

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A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice.
Pascal Heitel, Giuseppe Faudone, Moritz Helmstädter, Jurema Schmidt, Astrid Kaiser, Julius Pollinger

Commun Chem· November 2020

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Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms.
Apirat Chaikuad, Julius Pollinger, Michael Rühl, Xiaomin Ni, Whitney Kilu

Int J Mol Sci· November 2020

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Design and Structural Optimization of Dual FXR/PPARδ Activators.
Simone Schierle, Sebastian Neumann, Pascal Heitel, Sabine Willems, Astrid Kaiser, Julius Pollinger

J Med Chem· August 2020

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l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.
Leonie Gellrich, Pascal Heitel, Jan Heering, Whitney Kilu, Julius Pollinger

J Med Chem· July 2020

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A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences.
Julius Pollinger, Simone Schierle, Leonie Gellrich, Julia Ohrndorf, Astrid Kaiser

ACS Med Chem Lett· September 2019

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Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα Modulator.
Julius Pollinger, Simone Schierle, Sebastian Neumann, Julia Ohrndorf, Astrid Kaiser

ChemMedChem· July 2019

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Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.
Julius Pollinger, Leonie Gellrich, Simone Schierle, Whitney Kilu, Jurema Schmidt

J Med Chem· February 2019

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Allosteric modulation of the farnesoid X receptor by a small molecule.
Matthias Gabler, Jan Kramer, Jurema Schmidt, Julius Pollinger, Julia Weber

Sci Rep· May 2018

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Therapeutic applications of the versatile fatty acid mimetic WY14643.
Julius Pollinger, Daniel Merk

Expert Opin Ther Pat· April 2017

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