Publications by authors named "Michael J. Forrest"

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Chronic Inhibition of Renal Outer Medullary Potassium Channel Not Only Prevented but Also Reversed Development of Hypertension and End-Organ Damage in Dahl Salt-Sensitive Rats.
Xiaoyan Zhou, Michael J Forrest, Wanda Sharif-Rodriguez, Gail Forrest, Daphne Szeto

Hypertension· February 2017

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Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats.
Xiaoyan Zhou, Chin-hu Huang, Julie Lao, Alessandro Pocai, Gail Forrest, Michael J Forrest

Cardiovasc Diabetol· March 2015

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Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension.
Xiaoyan Zhou, Martin F Crook, Wanda Sharif-Rodriguez, Yonghua Zhu, Zadok Ruben, Gail Forrest, Michael J Forrest

Clin Exp Hypertens· March 2012

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On- and off-target pharmacology of torcetrapib: current understanding and implications for the structure activity relationships (SAR), discovery and development of cholesteryl ester-transfer protein (CETP) inhibitors.
Douglas G Johns, Joseph Duffy, Timothy Fisher, Brian K Hubbard, Michael J Forrest

Drugs· March 2012

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A potent and selective indole N-type calcium channel (Ca(v)2.2) blocker for the treatment of pain.
Sriram Tyagarajan, Prasun K Chakravarty, Min Park, Bishan Zhou, James B Herrington, Michael J Forrest

Bioorg Med Chem Lett· January 2011

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Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.
Hong C Shen, Fa-Xiang Ding, Subharekha Raghavan, Qiaolin Deng, Silvi Luell, Michael J Forrest

J Med Chem· March 2010

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A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis.
Matthew Walker, Barry R Campbell, Karim Azer, Christopher Tong, Kaijie Fang, Michael J Forrest

Atherosclerosis· May 2009

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Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat.
Amjad Ali, James M Balkovec, Mark Greenlee, Milton L Hammond, Greg Rouen, Michael J Forrest

Bioorg Med Chem· August 2008

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Comparison of rat and dog models of vasodilatation and lipolysis for the calculation of a therapeutic index for GPR109A agonists.
Ester Carballo-Jane, Lynn S Gerckens, Silvi Luell, Allison S Parlapiano, Michael Wolff, Michael J Forrest

J Pharmacol Toxicol Methods· January 2008

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Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor.
Hong C Shen, Fa-Xiang Ding, Silvi Luell, Michael J Forrest, Ester Carballo-Jane

J Med Chem· December 2007

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Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: synthesis, in vitro profile, molecular modeling studies, and in vivo experiments.
Christopher F Thompson, Nazia Quraishi, Amjad Ali, Ralph T Mosley, James R Tata, Michael J Forrest

Bioorg Med Chem Lett· June 2007

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Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes.
Irwin I Singer, Min Tian, L Alexandra Wickham, Jeffrey Lin, Scaria S Matheravidathu, Michael J Forrest

J Immunol· December 2005

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Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity.
Cameron J Smith, Amjad Ali, James M Balkovec, Donald W Graham, Milton L Hammond, Michael J Forrest

Bioorg Med Chem Lett· June 2005

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Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia.
Kun Liu, Libo Xu, Joel P Berger, Karen L Macnaul, Gauchao Zhou, Michael J Forrest

J Med Chem· April 2005

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Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy.
Christopher F Thompson, Nazia Quraishi, Amjad Ali, James R Tata, Milton L Hammond, Michael J Forrest

Bioorg Med Chem Lett· April 2005

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Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity.
Amjad Ali, Christopher F Thompson, James M Balkovec, Donald W Graham, Milton L Hammond, Michael J Forrest

J Med Chem· May 2004

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Skeletal muscle: a dual system to measure glucocorticoid-dependent transactivation and transrepression of gene regulation.
Ester Carballo-Jane, Shilpa Pandit, Joseph C Santoro, Concetta Freund, Silvi Luell, Michael J Forrest

J Steroid Biochem Mol Biol· February 2004

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Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.
Scott D Edmondson, Anthony Mastracchio, Jiafang He, Christine C Chung, Michael J Forrest

Bioorg Med Chem Lett· November 2003

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O-arylmandelic acids as highly selective human PPAR alpha/gamma agonists.
Alan D Adams, Zao Hu, Derek von Langen, Adonis Dadiz, Alex Elbrecht, Michael J Forrest

Bioorg Med Chem Lett· October 2003

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Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2.
Catherine Abbadie, Jill A Lindia, Anne Marie Cumiskey, Larry B Peterson, John S Mudgett, Michael J Forrest

Proc Natl Acad Sci U S A· June 2003

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Sphingosine-1-phosphate receptor agonism impairs the efficiency of the local immune response by altering trafficking of naive and antigen-activated CD4+ T cells.
Jenny H Xie, Naomi Nomura, Sam L Koprak, Elizabeth J Quackenbush, Michael J Forrest

J Immunol· April 2003

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Comparison of Cardiovascular Parameters and/or Serum Chemistry and Hematology Profiles in Conscious and Anesthetized Rhesus Monkeys (Macaca mulatta).
Gary J. Hom, Thomas J. Bach, Dayna Carroll, Michael J. Forrest, Michele A. Mariano

Contemp Top Lab Anim Sci· March 1999

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