Publications by authors named "Neal Green"

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Antitumor Efficacy of 1,2,4-Triazole-Based VCP/p97 Allosteric Inhibitors.
Neal Green, Matthew G LaPorte, William Paquette, Sipak Joyasawal, Pravat Mondal

J Med Chem· July 2025

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Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer.
Matthew G LaPorte, Celeste Alverez, Alexander Chatterley, Marina Kovaliov, Evan J Carder, Neal Green

ACS Med Chem Lett· July 2023

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Optimization of ether and aniline based inhibitors of lactate dehydrogenase.
Plamen P Christov, Kwangho Kim, Somnath Jana, Ian M Romaine, Ganesha Rai, Neal Green

Bioorg Med Chem Lett· June 2021

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Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97.
Matthew G LaPorte, James C Burnett, Raffaele Colombo, Stacie L Bulfer, Celeste Alverez, Neal Green

ACS Med Chem Lett· November 2018

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.
Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Prashant Rao, Stacie L Bulfer, Neal Green

Science· February 2016

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Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway.
Celeste Alverez, Stacie L Bulfer, Ramappa Chakrasali, Michael S Chimenti, Raymond J Deshaies, Neal Green

ACS Med Chem Lett· February 2016

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Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood.
Junjun Wu, Neal Green, Rajeev Hotchandani, Yonghan Hu, Jeffrey Condon

Bioorg Med Chem Lett· July 2009

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Benzhydrylquinazolinediones: novel cytosolic phospholipase A2alpha inhibitors with improved physicochemical properties.
Steven J Kirincich, Jason Xiang, Neal Green, Steve Tam, Hui Y Yang

Bioorg Med Chem· July 2009

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Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood.
J Perry Hall, Yahya Kurdi, Sang Hsu, John Cuozzo, Julie Liu, Neal Green

J Biol Chem· November 2007

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Identification of a novel class of selective Tpl2 kinase inhibitors: 4-Alkylamino-[1,7]naphthyridine-3-carbonitriles.
Neelu Kaila, Neal Green, Huan-Qiu Li, Yonghan Hu, Kristin Janz

Bioorg Med Chem· October 2007

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Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles.
Neal Green, Yonghan Hu, Kristin Janz, Huan-Qiu Li, Neelu Kaila

J Med Chem· September 2007

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A rat pharmacokinetic/pharmacodynamic model for assessment of lipopolysaccharide-induced tumor necrosis factor-alpha production.
Qin Wang, Yuhua Zhang, J Perry Hall, Lih-Ling Lin, Uma Raut, Neal Green

J Pharmacol Toxicol Methods· August 2007

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Inhibition of Tpl2 kinase and TNFalpha production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis.
Yonghan Hu, Neal Green, Lori K Gavrin, Kristin Janz, Neelu Kaila

Bioorg Med Chem Lett· December 2006

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Inhibition of Tpl2 kinase and TNF-alpha production with 1,7-naphthyridine-3-carbonitriles: synthesis and structure-activity relationships.
Lori Krim Gavrin, Neal Green, Yonghan Hu, Kristin Janz, Neelu Kaila

Bioorg Med Chem Lett· December 2005

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Structure-activity studies of a series of dipyrazolo[3,4-b:3',4'-d]pyridin-3-ones binding to the immune regulatory protein B7.1.
Neal J Green, Jason Xiang, Jing Chen, Lihren Chen, Audrey M Davies

Bioorg Med Chem· July 2003

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Total synthesis of rhizoxin D, a potent antimitotic agent from the fungus Rhizopus chinensis.
James D White, Paul R Blakemore, Neal J Green, E Bryan Hauser, Mark A Holoboski

J Org Chem· November 2002

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