Publications by authors named "Neil Mathias"

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Investigating Weak Polypeptide-Cyclodextrin Interactions in Biologic Formulation Development Using Affinity Capillary Electrophoresis and Flow-Induced Dispersion Analysis.
Yunxiao Zhu, Sharadvi Thati, Megan Mccallum, Rao Mantri, William Ying, Neil Mathias

Electrophoresis· September 2025

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The efficacy of cellulose dressings in burn wound management: a systematic review and meta-analysis.
Tristan Hill, Abdal Qadir Zafar, Tal D Ellenbogen, Neil C Mathias, Neil D Muscat

Burns· February 2025

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Towards more tolerable subcutaneous administration: Review of contributing factors for improving combination product design.
Neil Mathias, Sylvain Huille, Marie Picci, Robert P Mahoney, Ronald J Pettis

Adv Drug Deliv Rev· June 2024

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Strategies for Managing Solid Form Transformation Risk in Drug Product.
Umesh Kestur, Anisha Patel, Sherif Badawy, Neil Mathias, Limin Zhang

J Pharm Sci· April 2023

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Utilization of In Vitro, In Vivo and In Silico Tools to Evaluate the pH-Dependent Absorption of a BCS Class II Compound and Identify a pH-Effect Mitigating Strategy.
Christoph Gesenberg, Neil R Mathias, Yan Xu, John Crison, Ishani Savant

Pharm Res· October 2019

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Bioavailability of protein therapeutics in rats following inhalation exposure: Relevance to occupational exposure limit calculations.
Janet C Gould, Irvith Carvajal, Todd Davidson, Jessica Graham, Jedd Hillegass, Neil Mathias

Regul Toxicol Pharmacol· December 2018

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Characterization of a Liquid Crystal System for Sustained Release of a Peptide BMS-686117.
Yan Xu, Vivian Li, Jinjiang Li, Duohai Pan, Gerd Langenbucher, Neil Mathias

AAPS PharmSciTech· January 2018

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Biopharmaceutical Evaluation and CMC Aspects of Oral Modified Release Formulations.
Rong-Kun Chang, Neil Mathias, Munir A Hussain

AAPS J· September 2017

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Mitigation of Adverse Clinical Events of a Narrow Target Therapeutic Index Compound through Modified Release Formulation Design: An in Vitro, in Vivo, in Silico, and Clinical Pharmacokinetic Analysis.
David J Good, Ruiling Hartley, Neil Mathias, John Crison, Giridhar Tirucherai

Mol Pharm· December 2015

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Food Effect in Humans: Predicting the Risk Through In Vitro Dissolution and In Vivo Pharmacokinetic Models.
Neil Mathias, Yan Xu, Balvinder Vig, Umesh Kestur, Amy Saari

AAPS J· July 2015

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From bench to humans: formulation development of a poorly water soluble drug to mitigate food effect.
Preetanshu Pandey, Rhye Hamey, Dilbir S Bindra, Zongyun Huang, Neil Mathias

AAPS PharmSciTech· April 2014

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Application of imaging based tools for the characterisation of hollow spray dried amorphous dispersion particles.
John F Gamble, Ana P Ferreira, Mike Tobyn, Lynn DiMemmo, Kyle Martin, Neil Mathias

Int J Pharm· April 2014

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Assessing the risk of pH-dependent absorption for new molecular entities: a novel in vitro dissolution test, physicochemical analysis, and risk assessment strategy.
Neil R Mathias, Yan Xu, Dhaval Patel, Michael Grass, Brett Caldwell

Mol Pharm· November 2013

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Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery.
Prasad V Chaturvedula, Stephen E Mercer, Sokhom S Pin, George Thalody, Cen Xu, Neil Mathias

Bioorg Med Chem Lett· June 2013

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The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2.
Xiaojun Han, Rita L Civiello, Charles M Conway, Deborah A Cook, Carl D Davis, Neil R Mathias

Bioorg Med Chem Lett· March 2013

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Solution behavior of PVP-VA and HPMC-AS-based amorphous solid dispersions and their bioavailability implications.
Feng Qian, Jennifer Wang, Ruiling Hartley, Jing Tao, Raja Haddadin, Neil Mathias

Pharm Res· October 2012

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The use of modeling tools to drive efficient oral product design.
Neil R Mathias, John Crison

AAPS J· September 2012

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Non-invasive systemic drug delivery: developability considerations for alternate routes of administration.
Neil R Mathias, Munir A Hussain

J Pharm Sci· January 2010

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Rat nasal lavage biomarkers to assess preclinical irritation potential of nasal drug formulations and excipients.
Neil R Mathias, Paul Moench, Christopher Heran, Munir A Hussain, Ronald L Smith

J Pharm Sci· February 2009

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Pulmonary delivery of a GLP-1 receptor agonist, BMS-686117.
Feng Qian, Neil Mathias, Paul Moench, Cecilia Chi, Sridhar Desikan

Int J Pharm· January 2009

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Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure.
Andrew P Degnan, Prasad V Chaturvedula, Charles M Conway, Deborah A Cook, Carl D Davis, Neil R Mathias

J Med Chem· August 2008

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Modulation of tight junctions does not predict oral absorption of hydrophilic compounds: use of Caco-2 and Calu-3 cells.
Amrita V Kamath, Richard A Morrison, Neil R Mathias, Sandra A Dando, Anthony M Marino

Arch Pharm Res· August 2007

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Nucleoside transport in primary cultured rabbit tracheal epithelial cells.
Neil R Mathias, Sharon K Wu, Kwang-Jin Kim, Vincent H L Lee

J Drug Target· March 2006

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Carbopol-mediated paracellular transport enhancement in Calu-3 cell layers.
Lianli Li, Neil R Mathias, Christopher L Heran, Paul Moench, Doris A Wall

J Pharm Sci· February 2006

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A rabbit model for sublingual drug delivery: comparison with human pharmacokinetic studies of propranolol, verapamil and captopril.
Manisha M Dali, Paul A Moench, Neil R Mathias, Paul I Stetsko, Christopher L Heran

J Pharm Sci· January 2006

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