Publications by authors named "Nicholas G Fox"

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Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling.
Nadine Alvarez, Gregory C Adam, John A Howe, Vijeta Sharma, Matthew D Zimmerman, Nicholas G Fox

Viruses· July 2024

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Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic.
Valerie W Shurtleff, Mark E Layton, Craig A Parish, James J Perkins, John D Schreier, Nicholas G Fox

J Med Chem· March 2024

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Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
Nicholas G Fox, Xiaodi Yu, Xidong Feng, Henry J Bailey, Alain Martelli

Nat Commun· May 2019

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4'-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function.
Jaimeen D Majmudar, Xidong Feng, Nicholas G Fox, Joseph F Nabhan, Theresa Towle

Medchemcomm· February 2019

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Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity.
Nicholas G Fox, Alain Martelli, Joseph F Nabhan, Jay Janz, Oktawia Borkowska

Biochimie· September 2018

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The Human Iron-Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules.
Nicholas G Fox, Mrinmoy Chakrabarti, Sean P McCormick, Paul A Lindahl, David P Barondeau

Biochemistry· June 2015

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Frataxin Accelerates [2Fe-2S] Cluster Formation on the Human Fe-S Assembly Complex.
Nicholas G Fox, Deepika Das, Mrinmoy Chakrabarti, Paul A Lindahl, David P Barondeau

Biochemistry· June 2015

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Human frataxin activates Fe-S cluster biosynthesis by facilitating sulfur transfer chemistry.
Jennifer Bridwell-Rabb, Nicholas G Fox, Chi-Lin Tsai, Andrew M Winn, David P Barondeau

Biochemistry· August 2014

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Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template.
Monika M Meier, Chitra Rajendran, Christoph Malisi, Nicholas G Fox, Chengfu Xu

J Am Chem Soc· August 2013

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