Publications by authors named "Peter M Clark"

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Blocking Deoxycytidine Kinase in Activated Lymphocytes Depletes Deoxycytidine Triphosphate Pools and Alters Cell Cycle Kinetics to Yield Less Disease in a Mouse Multiple Sclerosis Model.
Jessica R Salas, K M Ryan, Alyssa O Trias, Bao Ying Chen, Miriam Guemes, Peter M Clark

Immunology· February 2025

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EGGNet, a Generalizable Geometric Deep Learning Framework for Protein Complex Pose Scoring.
Zichen Wang, Ryan Brand, Jared Adolf-Bryfogle, Jasleen Grewal, Yanjun Qi, Peter M Clark

ACS Omega· February 2024

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Early Reduction of Glucose Consumption Is a Biomarker of Kinase Inhibitor Efficacy Which Can Be Reversed with GLUT1 Overexpression in Lung Cancer Cells.
Chiara Ghezzi, Stefani Perez, Kaitlin Ryan, Alicia Wong, Bao Ying Chen, Peter M Clark

Mol Imaging Biol· June 2023

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Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis.
Bao Ying Chen, Jessica R Salas, Alyssa O Trias, Arely Perez Rodriguez, Jonathan E Tsang, Peter M Clark

Immunology· January 2023

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Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3.
Chiara Ghezzi, Bao Ying Chen, Robert Damoiseaux, Peter M Clark

Sci Rep· January 2023

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Signaling Pathways That Drive F-FDG Accumulation in Cancer.
Jessica R Salas, Peter M Clark

J Nucl Med· May 2022

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LM-GVP: an extensible sequence and structure informed deep learning framework for protein property prediction.
Zichen Wang, Steven A Combs, Ryan Brand, Miguel Romero Calvo, Panpan Xu, Peter M Clark

Sci Rep· April 2022

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Correction to: ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing.
Camilo Breton, Peter M Clark, Lili Wang, Jenny A Greig, James M Wilson

BMC Genomics· November 2020

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Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors.
Jonathan E Tsang, Lorenz M Urner, Gyudong Kim, Kingsley Chow, Lynn Baufeld, Peter M Clark

ACS Med Chem Lett· October 2020

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AnthOligo: automating the design of oligonucleotides for capture/enrichment technologies.
Pushkala Jayaraman, Timothy Mosbruger, Taishan Hu, Nikolaos G Tairis, Chao Wu, Peter M Clark

Bioinformatics· August 2020

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F-FAC PET Visualizes Brain-Infiltrating Leukocytes in a Mouse Model of Multiple Sclerosis.
Bao Ying Chen, Chiara Ghezzi, Brendon Villegas, Andrew Quon, Caius G Radu, Peter M Clark

J Nucl Med· May 2020

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ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing.
Camilo Breton, Peter M Clark, Lili Wang, Jenny A Greig, James M Wilson

BMC Genomics· March 2020

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A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.
Liang Wang, Bryan A Smith, Nikolas G Balanis, Brandon L Tsai, Kim Nguyen, Peter M Clark

Proc Natl Acad Sci U S A· January 2020

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Rapid, efficient, and economical synthesis of PET tracers in a droplet microreactor: application to O-(2-[F]fluoroethyl)-L-tyrosine ([F]FET).
Ksenia Lisova, Bao Ying Chen, Jia Wang, Kelly Mun-Ming Fong, Peter M Clark

EJNMMI Radiopharm Chem· December 2019

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A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells.
Chiara Ghezzi, Alicia Wong, Bao Ying Chen, Bernard Ribalet, Robert Damoiseaux, Peter M Clark

Nat Commun· November 2019

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The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier.
Juliette Hordeaux, Yuan Yuan, Peter M Clark, Qiang Wang, R Alexander Martino

Mol Ther· May 2019

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F-FAC PET Selectively Images Liver-Infiltrating CD4 and CD8 T Cells in a Mouse Model of Autoimmune Hepatitis.
Jessica R Salas, Bao Ying Chen, Alicia Wong, Donghui Cheng, John S Van Arnam, Peter M Clark

J Nucl Med· October 2018

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Noninvasive Imaging of Drug-Induced Liver Injury with F-DFA PET.
Jessica R Salas, Bao Ying Chen, Alicia Wong, Sergio Duarte, Stephanie A K Angarita, Peter M Clark

J Nucl Med· August 2018

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Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis.
Haruko Nakano, Itsunari Minami, Daniel Braas, Herman Pappoe, Xiuju Wu, Peter M Clark

Elife· December 2017

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Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma.
Wilson X Mai, Laura Gosa, Veerle W Daniels, Lisa Ta, Jonathan E Tsang, Peter M Clark

Nat Med· November 2017

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Harnessing Preclinical Molecular Imaging to Inform Advances in Personalized Cancer Medicine.
Peter M Clark, Victoria A Ebiana, Laura Gosa, Timothy F Cloughesy, David A Nathanson

J Nucl Med· May 2017

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N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration.
Isidore Rigoutsos, Sang Kil Lee, Su Youn Nam, Simone Anfossi, Barbara Pasculli, Peter M Clark

Genome Biol· May 2017

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An Expanded Role for HLA Genes: Encodes a microRNA that Regulates IgA and Other Immune Response Transcripts.
Nilesh Chitnis, Peter M Clark, Malek Kamoun, Catherine Stolle, F Brad Johnson

Front Immunol· May 2017

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Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.
Yun Dai, Yuanzi Zhao, Masatoshi Tomi, Bo-Chul Shin, Shanthie Thamotharan, Peter M Clark

Endocrinology· April 2017

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Generation of Full-Length Class I Human Leukocyte Antigen Gene Consensus Sequences for Novel Allele Characterization.
Peter M Clark, Jamie L Duke, Deborah Ferriola, Valia Bravo-Egana, Tunde Vago

Clin Chem· December 2016

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