Publications by authors named "Pierre Savi"

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Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes.
Douglas A MacDonald, Joel Martin, Kathir K Muthusamy, Jiann-Kae Luo, Erica Pyles, Pierre Savi

Angiogenesis· July 2016

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A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury.
Sandrine Delbary-Gossart, Sangmi Lee, Marco Baroni, Isabelle Lamarche, Michele Arnone, Pierre Savi

Brain· June 2016

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Regulator of G-protein signaling 18 controls both platelet generation and function.
Nathalie Delesque-Touchard, Caroline Pendaries, Cécile Volle-Challier, Laurence Millet, Véronique Salel, Pierre Savi

PLoS One· April 2016

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N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
Christophe Boldron, Angélina Besse, Marie-Françoise Bordes, Stéphanie Tissandié, Xavier Yvon, Pierre Savi

J Med Chem· September 2014

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Specific Inhibition of the VEGFR-3 Tyrosine Kinase by SAR131675 Reduces Peripheral and Tumor Associated Immunosuppressive Myeloid Cells.
Nicolas Espagnolle, Pauline Barron, Marie Mandron, Isabelle Blanc, Jacques Bonnin, Pierre Savi

Cancers (Basel)· February 2014

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P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development.
Michael Horckmans, Bernard Robaye, Elvira Léon-Gόmez, Nicolas Lantz, Philippe Unger, Pierre Savi

Angiogenesis· September 2012

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SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities.
Antoine Alam, Isabelle Blanc, Geneviève Gueguen-Dorbes, Olivier Duclos, Jacques Bonnin, Pierre Savi

Mol Cancer Ther· August 2012

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Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells.
Sandrine Chamboredon, Delphine Ciais, Agnès Desroches-Castan, Pierre Savi, Françoise Bono

Mol Biol Cell· September 2011

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An improved method for specific and quantitative determination of the clopidogrel active metabolite isomers in human plasma.
Gilles Tuffal, Sebastien Roy, Melanie Lavisse, Denis Brasseur, Joe Schofield, Pierre Savi

Thromb Haemost· April 2011

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Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.
Krishna Saxena, Ulrich Schieborr, Oliver Anderka, Elke Duchardt-Ferner, Bettina Elshorst, Pierre Savi

J Biol Chem· August 2010

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Soluble HLA-G1 inhibits angiogenesis through an apoptotic pathway and by direct binding to CD160 receptor expressed by endothelial cells.
Pierre Fons, Sophie Chabot, Judith E Cartwright, Francoise Lenfant, Fatima L'Faqihi, Pierre Savi

Blood· October 2006

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Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.
Benoit Favier, Antoine Alam, Pauline Barron, Jacques Bonnin, Patricia Laboudie, Pierre Savi

Blood· August 2006

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The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts.
Pierre Savi, Jean-Luc Zachayus, Nathalie Delesque-Touchard, Catherine Labouret, Caroline Hervé

Proc Natl Acad Sci U S A· July 2006

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Clopidogrel for the secondary prevention of stroke.
Hans-Christoph Diener, Peter A Ringleb, Pierre Savi

Expert Opin Pharmacother· May 2005

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Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis.
Pierre Savi, Jean-Marc Herbert

Semin Thromb Hemost· April 2005

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P2Y receptor antagonists in thrombosis.
Jean-Marie Boeynaems, Hans van Giezen, Pierre Savi, Jean-Marc Herbert

Curr Opin Investig Drugs· March 2005

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Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.
Anne Angelillo-Scherrer, Laurent Burnier, Nathalie Flores, Pierre Savi, Maria DeMol

J Clin Invest· February 2005

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Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin.
Pierre Savi, Beng H Chong, Andreas Greinacher, Yves Gruel, John G Kelton

Blood· January 2005

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Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors.
Xuri Li, Marc Tjwa, Lieve Moons, Pierre Fons, Agnes Noel, Pierre Savi

J Clin Invest· January 2005

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Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.
Antoine Alam, Jean-Pascal Herault, Pauline Barron, Benoit Favier, Pierre Fons, Pierre Savi

Biochem Biophys Res Commun· November 2004

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Use of radiolabeled 2-methylthio-ADP to study P2Y receptors on platelets and cell lines.
Pierre Savi, Jean-Marc Herbert

Methods Mol Biol· October 2004

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The antiaggregating activity of clopidogrel is not affected by N-acetyl L-cysteine.
Alain Lalé, Jean-Marc Herbert, Pierre Savi

Thromb Haemost· November 2003

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Pharmacological characterization of the human P2Y13 receptor.
Frederic Marteau, Emmanuel Le Poul, David Communi, Didier Communi, Catherine Labouret, Pierre Savi

Mol Pharmacol· July 2003

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P2Y12, a new platelet ADP receptor, target of clopidogrel.
Jean-Marc Herbert, Pierre Savi

Semin Vasc Med· May 2003

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Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Jean O Contreres, Evelyne Dupuy, Bernard Job, Aïda Habib, Margke Bryckaert, Pierre Savi

Br J Haematol· February 2003

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