Publications by authors named "Ramnik Xavier"

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Microbiome-derived bile acid signatures in early life and their association with islet autoimmunity.
Santosh Lamichhane, Alex M Dickens, Tanja Buchacher, Tianai Lou, Vincent Charron-Lamoureux, Ramnik J Xavier

Nat Commun· December 2025

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Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulation.
Jinjin Xu, Lingjia Kong, Elizabeth A Creasey, Sneha Rath, Lei Deng, Ramnik J Xavier

J Exp Med· November 2025

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Human immunodeficiency virus and antiretroviral therapies exert distinct influences across diverse gut microbiomes.
Karolina S Jabbar, Sambhawa Priya, Jiawu Xu, Upasana Das Adhikari, Gleb Pishchany, Ramnik J Xavier

Nat Microbiol· November 2025

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Allosteric modulation of the solute carrier transporter SLC39A8 potentiates manganese and cadmium uptake.
Kelly L Damm-Ganamet, Clara Moon, Alan D Wickenden, Mark Tichenor, Yunhui Ge, Ramnik J Xavier

J Clin Invest· November 2025

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Protein language models uncover carbohydrate-active enzyme function in metagenomics.
Kumar Thurimella, Ahmed M T Mohamed, Chenhao Li, Tommi Vatanen, Daniel B Graham, Ramnik J Xavier

BMC Bioinformatics· November 2025

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Delayed Remission With Advanced Therapies Is Not Associated With Worse One-Year Outcomes In Inflammatory Bowel Disease.
Sara Ghoneim, Heather Choe, Leo Boneschansker, Karan Sachdeva, Helena Lau, Ramnik Xavier

Am J Gastroenterol· October 2025

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Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation.
Peng Tan, Alok Jaiswal, Shane P Murphy, Eric M Brown, Hailey Wheeler, Ramnik J Xavier

Science· October 2025

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Convergent genomic responses of human gut bacteria to variations in industrialization.
Malte Rühlemann, Lénárd L Szánthó, Silvio Waschina, Lucas Moitinho-Silva, Laura K Mews, Ramnik Xavier

bioRxiv· October 2025

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Industrialization drives convergent microbial and physiological shifts in the human metaorganism.
Mathilde Poyet, Malte Rühlemann, Ana P Schaan, Yue Ma, Lucas Moitinho-Silva, Ramnik J Xavier

bioRxiv· October 2025

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Nuclear receptor coregulator NRIP1 R448G modulates T cell gut homing to control intestinal inflammation.
Xiangjun Chen, Hee Seung Hwang, Bihua Li, Yanhua Zhao, Koushik Ghosh, Ramnik J Xavier

Proc Natl Acad Sci U S A· September 2025

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A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity.
Kamil Slowikowski, Pritha Sen, Christopher V Cosgriff, Jessica Tantivit, Tom Eisenhaure, Ramnik Xavier

medRxiv· September 2025

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Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.
John D Rioux, Gabrielle Boucher, Anik Forest, Bertrand Bouchard, Lise Coderre, Ramnik J Xavier

Immunol Cell Biol· August 2025

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Elucidating the role of -derived indole metabolites in gut inflammation and immune modulation.
Jong-Duk Park, Seoung Rak Lee, Catherine Dhennezel, Noel Taylor, Andrea Dame, Ramnik J Xavier

Proc Natl Acad Sci U S A· August 2025

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Type 2 cytokines act on enteric sensory neurons to regulate neuropeptide-driven host defense.
Rocky M Barilla, Clara Berard, Linyu Sun, Sumiti Sandhu, Sarah Zaghouani, Ramnik J Xavier

Science· July 2025

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Single-cell and spatial transcriptomics of stricturing Crohn's disease highlights a fibrosis-associated network.
Lingjia Kong, Sathish Subramanian, Åsa Segerstolpe, Vy Tran, Angela R Shih, Ramnik J Xavier

Nat Genet· July 2025

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An International Multicenter Study of Native and Immigrant South Asian Crohn's Disease.
Maryam K Ibrahim, Rebecca Cohen, Tarun Chhibba, Mukesh Kumar, Helena Lau, Ramnik Xavier

Clin Gastroenterol Hepatol· July 2025

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Produces a Cryptic Pro-inflammatory Lipid.
Yern-Hyerk Shin, Sunghee Bang, Ramnik Xavier, Jon Clardy

J Am Chem Soc· July 2025

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Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway.
Eric M Brown, Emily R Temple, Sarah Jeanfavre, Julian Avila-Pacheco, Noel Taylor, Ramnik J Xavier

Cell Host Microbe· June 2025

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Intelectin-2 is a broad-spectrum antimicrobial lectin.
Amanda E Dugan, Deepsing Syangtan, Eric B Nonnecke, Rajeev S Chorghade, Amanda L Peiffer, Ramnik J Xavier

bioRxiv· June 2025

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Association of distinct microbial and metabolic signatures with microscopic colitis.
Albert Sheng-Yin Chen, Hanseul Kim, Etienne Nzabarushimana, Jiaxian Shen, Katherine Williams, Ramnik J Xavier

Nat Commun· May 2025

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Correction to "Unusual Phospholipids from Linked to Depression".
Sunghee Bang, Yern-Hyerk Shin, Sung-Moo Park, Lei Deng, R Thomas Williamson, Ramnik J Xavier

J Am Chem Soc· April 2025

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Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator.
Zher Yin Tan, Joel K A Adade, Xiebin Gu, Cody J S Hecht, Michael Salcius, Ramnik J Xavier

Cell Chem Biol· March 2025

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The Ulcerative Colitis-Associated Gene NXPE1 Catalyzes Glycan Modifications on Colonic Mucin.
Ranad Humeidi, Noriko Oshiro-Rapley, Xiebin Gu, Joon Soo An, Ashwin N Ananthakrishnan, Ramnik J Xavier

J Am Chem Soc· March 2025

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Trajectories of microbiome-derived bile acids in early life - insights into the progression to islet autoimmunity.
Santosh Lamichhane, Alex M Dickens, Tanja Buchacher, Evita Tianai Lou, Vincent Charron-Lamoureux, Ramnik J Xavier

medRxiv· February 2025

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Unusual Phospholipids from Linked to Depression.
Sunghee Bang, Yern-Hyerk Shin, Sung-Moo Park, Lei Deng, R Thomas Williamson, Ramnik J Xavier

J Am Chem Soc· January 2025

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