Publications by authors named "Remy Morgentin"

Claim this Profile
N
Novel library synthesis of 3,4-disubstituted pyridin-2(1)-ones via cleavage of pyridine-2-oxy-7-azabenzotriazole ethers under ionic hydrogenation conditions at room temperature.
Romain Pierre, Anne Brethon, Sylvain A Jacques, Aurélie Blond, Sandrine Chambon, Rémy Morgentin

Beilstein J Org Chem· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory.
Remy Morgentin, Mark Dow, Anthony Aimon, George Karageorgis, Tuomo Kalliokoski

Drug Discov Today· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Squaramides as novel class I and IIB histone deacetylase inhibitors for topical treatment of cutaneous t-cell lymphoma.
Jean-François Fournier, Yushma Bhurruth-Alcor, Branislav Musicki, Jérome Aubert, Michèle Aurelly, Rémy Morgentin

Bioorg Med Chem Lett· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Realisation of small molecule libraries based on frameworks distantly related to natural products.
Anthony Aimon, George Karageorgis, Jacob Masters, Mark Dow, Philip G E Craven, Rémy Morgentin

Org Biomol Chem· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.
Bernard Barlaam, Sabina Cosulich, Sébastien Degorce, Rebecca Ellston, Martina Fitzek, Rémy Morgentin

Bioorg Med Chem Lett· May 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A metal-catalyzed enyne-cyclization step for the synthesis of bi- and tricyclic scaffolds amenable to molecular library production.
Peng Wu, Michael Åxman Petersen, A Emil Cohrt, Rico Petersen, Rémy Morgentin

Org Biomol Chem· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a series of 8-(2,3-dihydro-1,4-benzoxazin-4-ylmethyl)-2-morpholino-4-oxo-chromene-6-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.
Bernard Barlaam, Sabina Cosulich, Sébastien Degorce, Martina Fitzek, Stephen Green, Rémy Morgentin

Bioorg Med Chem Lett· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction to Investigation of (E)-3-[4-(2-Oxo-3-aryl-chromen-4-yl)oxyphenyl]acrylic Acids as Oral Selective Estrogen Receptor Down-Regulators.
Sébastien L Degorce, Andrew Bailey, Rowena Callis, Chris De Savi, Richard Ducray, Rémy Morgentin

J Med Chem· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective.
Anna Karawajczyk, Fabrizio Giordanetto, Jorg Benningshof, Daniel Hamza, Tuomo Kalliokoski, Remy Morgentin

Drug Discov Today· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers.
Bernard Barlaam, Sabina Cosulich, Bénédicte Delouvrié, Rebecca Ellston, Martina Fitzek, Rémy Morgentin

Bioorg Med Chem Lett· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries.
Philip Craven, Anthony Aimon, Mark Dow, Nicolas Fleury-Bregeot, Rachel Guilleux, Remy Morgentin

Bioorg Med Chem· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis of 1,4,5 trisubstituted γ-lactams via a 3-component cascade reaction.
Michael Åxman Petersen, Michael A Mortensen, A Emil Cohrt, Rico Petersen, Peng Wu, Rémy Morgentin

Bioorg Med Chem· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigation of (E)-3-[4-(2-Oxo-3-aryl-chromen-4-yl)oxyphenyl]acrylic Acids as Oral Selective Estrogen Receptor Down-Regulators.
Sébastien L Degorce, Andrew Bailey, Rowena Callis, Chris De Savi, Richard Ducray, Rémy Morgentin

J Med Chem· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of (R)-8-(1-(3,5-difluorophenylamino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide (AZD8186): a potent and selective inhibitor of PI3Kβ and PI3Kδ for the treatment of PTEN-deficient cancers.
Bernard Barlaam, Sabina Cosulich, Sébastien Degorce, Martina Fitzek, Stephen Green, Rémy Morgentin

J Med Chem· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of 9-(1-anilinoethyl)-2-morpholino-4-oxo-pyrido[1,2-a]pyrimidine-7-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.
Bernard Barlaam, Sabina Cosulich, Sébastien Degorce, Martina Fitzek, Fabrizio Giordanetto, Rémy Morgentin

Bioorg Med Chem Lett· August 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of new quinoline ether inhibitors with high affinity and selectivity for PDGFR tyrosine kinases.
Patrick A Plé, Frédéric Jung, Sue Ashton, Laurent Hennequin, Romuald Laine, Rémy Morgentin

Bioorg Med Chem Lett· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of AZD2932, a new Quinazoline Ether Inhibitor with high affinity for VEGFR-2 and PDGFR tyrosine kinases.
Patrick A Plé, Frédéric Jung, Sue Ashton, Laurent Hennequin, Romuald Laine, Rémy Morgentin

Bioorg Med Chem Lett· January 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode.
M Raymond V Finlay, David G Acton, David M Andrews, Andrew J Barker, Michael Dennis, Rémy Morgentin

Bioorg Med Chem Lett· August 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor.
Laurent F Hennequin, Jack Allen, Jason Breed, Jon Curwen, Michael Fennell, Rémy Morgentin

J Med Chem· November 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket.
Peter Ballard, Robert H Bradbury, Craig S Harris, Laurent F A Hennequin, Mark Hickinson, Remy Morgentin

Bioorg Med Chem Lett· March 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New heterocyclic analogues of 4-(2-chloro-5-methoxyanilino)quinazolines as potent and selective c-Src kinase inhibitors.
Bernard Barlaam, Mike Fennell, Hervé Germain, Tim Green, Laurent Hennequin, Rémy Morgentin

Bioorg Med Chem Lett· December 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
5
5-Substituted 4-anilinoquinazolines as potent, selective and orally active inhibitors of erbB2 receptor tyrosine kinase.
Peter Ballard, Robert H Bradbury, Laurent F A Hennequin, D Mark Hickinson, Paul D Johnson, Remy Morgentin

Bioorg Med Chem Lett· October 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis