Publications by authors named "Robert Reamer"

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Asymmetric Formal Synthesis of the Long-Acting DPP-4 Inhibitor Omarigliptin.
Feng Peng, Yonggang Chen, Cheng-Yi Chen, Peter G Dormer, Amude Kassim, Robert A Reamer

J Org Chem· September 2017

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Enantioselective Synthesis of 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) via Enzymatic Desymmetrization.
Mark McLaughlin, Jongrock Kong, Kevin M Belyk, Billy Chen, Andrew W Gibson, Robert A Reamer

Org Lett· February 2017

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Promotion of a Ti-Mediated Mannich Reaction by a Proton Source.
John Limanto, Naoki Yoshikawa, Robert A Reamer, Lushi Tan, Andrew Brunskill

J Org Chem· January 2016

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N-Boc deprotection and isolation method for water-soluble zwitterionic compounds.
Zhijian Liu, Nobuyoshi Yasuda, Michael Simeone, Robert A Reamer

J Org Chem· December 2014

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Unusual pyrimidine participation: efficient stereoselective synthesis of potent dual orexin receptor antagonist MK-6096.
John Y L Chung, Yong-Li Zhong, Kevin M Maloney, Robert A Reamer, Jeffrey C Moore

Org Lett· November 2014

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Discovery and application of doubly quaternized cinchona-alkaloid-based phase-transfer catalysts.
Bangping Xiang, Kevin M Belyk, Robert A Reamer, Nobuyoshi Yasuda

Angew Chem Int Ed Engl· August 2014

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Ring-closing metathesis reactions of bis(enynes): selectivity and surprises.
Debra J Wallace, Robert A Reamer

J Org Chem· June 2014

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Enantioselective synthesis of an HCV NS5a antagonist.
Ian K Mangion, Cheng-yi Chen, Hongmei Li, Peter Maligres, Yonggang Chen, Robert A Reamer

Org Lett· May 2014

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Synthesis of α-hydroxyacetophenones.
Mark McLaughlin, Kevin M Belyk, Gang Qian, Robert A Reamer, Cheng-yi Chen

J Org Chem· June 2012

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Synthesis of antifungal glucan synthase inhibitors from enfumafungin.
Yong-Li Zhong, Donald R Gauthier, Yao-Jun Shi, Mark McLaughlin, John Y L Chung, Robert A Reamer

J Org Chem· April 2012

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Synthesis of vaniprevir (MK-7009): lactamization to prepare a 20-membered [corrected] macrocycle.
Zhiguo J Song, David M Tellers, Michel Journet, Jeffrey T Kuethe, David Lieberman, Robert A Reamer

J Org Chem· October 2011

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Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305).
Neil A Strotman, Carl A Baxter, Karel M J Brands, Ed Cleator, Shane W Krska, Robert A Reamer

J Am Chem Soc· June 2011

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Practical synthesis of functionalized 1,5-disubstituted 1,2,4-triazole derivatives.
Yingju Xu, Mark McLaughlin, Emily N Bolton, Robert A Reamer

J Org Chem· December 2010

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A general method for the synthesis of 3,5-diarylcyclopentenones via friedel-crafts acylation of vinyl chlorides.
Yingju Xu, Mark McLaughlin, Cheng-yi Chen, Robert A Reamer, Peter G Dormer

J Org Chem· July 2009

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Catalytic asymmetric synthesis of an HIV integrase inhibitor.
Yong-Li Zhong, Shane W Krska, Hua Zhou, Robert A Reamer, Jaemoon Lee

Org Lett· January 2009

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A case of remote asymmetric induction in the peptide-catalyzed desymmetrization of a bis(phenol).
Chad A Lewis, Jeffrey L Gustafson, Anna Chiu, Jaume Balsells, David Pollard, Robert A Reamer

J Am Chem Soc· December 2008

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A polar radical pair pathway to assemble the pyrimidinone core of the HIV integrase inhibitor raltegravir potassium.
Philip J Pye, Yong-Li Zhong, Gavin O Jones, Robert A Reamer, Kendall N Houk

Angew Chem Int Ed Engl· July 2008

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Chlorination/cyclodehydration of amino alcohols with SOCl2: an old reaction revisited.
Feng Xu, Bryon Simmons, Robert A Reamer, Edward Corley, Jerry Murry

J Org Chem· January 2008

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Stereoisomeric separation of pharmaceutical compounds using CE with a chiral crown ether.
Lili Zhou, Zhihao Lin, Robert A Reamer, Bing Mao, Zhihong Ge

Electrophoresis· August 2007

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Impurity profile tracking for active pharmaceutical ingredients: case reports.
Lili Zhou, Bing Mao, Robert Reamer, Tom Novak, Zhihong Ge

J Pharm Biomed Anal· June 2007

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Novel intramolecular reactivity of oximes: synthesis of cyclic and spiro-fused imines.
Cécile G Savarin, Christiane Grisé, Jerry A Murry, Robert A Reamer, David L Hughes

Org Lett· March 2007

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Phosphine-catalyzed cycloadditions of allenic ketones: new substrates for nucleophilic catalysis.
Debra J Wallace, Rachel L Sidda, Robert A Reamer

J Org Chem· February 2007

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Remote desymmetrization at near-nanometer group separation catalyzed by a miniaturized enzyme mimic.
Chad A Lewis, Anna Chiu, Michele Kubryk, Jaume Balsells, David Pollard, Robert A Reamer

J Am Chem Soc· December 2006

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Unique tandem Heck-lactamization naphthyridinone ring formation between acrylanilides and halogenated pyridines.
Raymond J Cvetovich, Robert A Reamer, Lisa DiMichele, John Y L Chung, Jennifer R Chilenski

J Org Chem· October 2006

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Practical asymmetric synthesis of a gamma-secretase inhibitor exploiting substrate-controlled intramolecular nitrile oxide-olefin cycloaddition.
Jeremy P Scott, Steven F Oliver, Karel M J Brands, Sarah E Brewer, Antony J Davies, Robert A Reamer

J Org Chem· April 2006

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