Publications by authors named "Sarah Bucknell"

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Preclinical pharmacokinetics, metabolism, and disposition of NXE0041178, a novel orally bioavailable agonist of the GPR52 receptor with potential for treatment of schizophrenia and related psychiatric disorders.
Simon Poulter, Nigel Austin, Stephen P Watson, Sarah J Bucknell, M Alistair O'Brien

Xenobiotica· March 2025

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The Identification of GPR52 Agonist HTL0041178, a Potential Therapy for Schizophrenia and Related Psychiatric Disorders.
Simon Poulter, Nigel Austin, Rachel Armstrong, Matt Barnes, Sarah Joanne Bucknell

ACS Med Chem Lett· April 2023

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Structure-Based Drug Discovery of -(()-3-(7-Methyl-1-indazol-5-yl)-1-oxo-1-((()-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine.
Sarah J Bucknell, Mark A Ator, Alastair J H Brown, Jason Brown, Andrew D Cansfield

J Med Chem· July 2020

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Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis.
Mathieu Rappas, Ammar A E Ali, Kirstie A Bennett, Jason D Brown, Sarah J Bucknell

J Med Chem· February 2020

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Early audit of renal complications in a new cardiac surgery service in Australia.
Stephen N Bolsin, Peter Stow, Sarah Bucknell

Heart Lung Circ· September 2004

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