Publications by authors named "Scott Novick"

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A ternary switch model governing ERα ligand binding domain conformation.
Daniel P McDougal, Jordan L Pederick, Scott J Novick, Blagojce Jovcevski, Annmaree K Warrender

Nat Commun· November 2025

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Structure of phosphorylated-like RssB, the adaptor delivering σ to the ClpXP proteolytic machinery, reveals an interface switch for activation.
Christiane Brugger, Jacob Schwartz, Scott Novick, Song Tong, Joel R Hoskins

J Biol Chem· December 2023

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Assembly of JAZ-JAZ and JAZ-NINJA complexes in jasmonate signaling.
X Edward Zhou, Yaguang Zhang, Jian Yao, Jie Zheng, Yuxin Zhou, Scott Novick

Plant Commun· November 2023

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Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Dipak N Patil, Serena Pantalone, Yan Cao, Thibaut Laboute, Scott J Novick

Sci Signal· July 2023

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Molecular glue CELMoD compounds are regulators of cereblon conformation.
Edmond R Watson, Scott Novick, Mary E Matyskiela, Philip P Chamberlain, Andres H de la Peña

Science· November 2022

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Patient-derived Siglec-6-targeting antibodies engineered for T-cell recruitment have potential therapeutic utility in chronic lymphocytic leukemia.
Matthew G Cyr, Maissa Mhibik, Junpeng Qi, Haiyong Peng, Jing Chang, Scott J Novick

J Immunother Cancer· November 2022

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Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex.
Dipak N Patil, Shikha Singh, Thibaut Laboute, Timothy S Strutzenberg, Xingyu Qiu, Scott J Novick

Science· January 2022

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Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.
Timothy S Strutzenberg, Yingmin Zhu, Scott J Novick, Ruben D Garcia-Ordonez, Christelle Doebelin

J Mol Biol· November 2021

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One-step construction of circularized nanodiscs using SpyCatcher-SpyTag.
Shanwen Zhang, Qian Ren, Scott J Novick, Timothy S Strutzenberg, Patrick R Griffin

Nat Commun· September 2021

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Dual-mechanism estrogen receptor inhibitors.
Jian Min, Jerome C Nwachukwu, Charles K Min, Jacqline W Njeri, Sathish Srinivasan, Scott Novick

Proc Natl Acad Sci U S A· August 2021

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Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay.
Ryan J Shirey, Jonathan R Hart, BanuPriya Sridharan, Scott J Novick, Lewis D Turner

Bioorg Med Chem· July 2021

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Structure of an AMPK complex in an inactive, ATP-bound state.
Yan Yan, Somnath Mukherjee, Kaleeckal G Harikumar, Timothy S Strutzenberg, X Edward Zhou, Scott J Novick

Science· July 2021

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Structures of the human LONP1 protease reveal regulatory steps involved in protease activation.
Mia Shin, Edmond R Watson, Albert S Song, Jeffrey T Mindrebo, Scott J Novick

Nat Commun· May 2021

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CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS.
Litao Sun, Na Wei, Bernhard Kuhle, David Blocquel, Scott Novick

Proc Natl Acad Sci U S A· March 2021

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Structure-Activity Relationship and Biological Investigation of SR18292 (), a Suppressor of Glucagon-Induced Glucose Production.
Hua Lin, Kfir Sharabi, Li Lin, Claudia Ruiz, Di Zhu, Scott J Novick

J Med Chem· January 2021

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Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.
Jie Zheng, Timothy S Strutzenberg, Adrian Reich, Venkatasubramanian Dharmarajan, Bruce D Pascal, Scott J Novick

Anal Chem· August 2020

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Design of an in vitro biocatalytic cascade for the manufacture of islatravir.
Mark A Huffman, Anna Fryszkowska, Oscar Alvizo, Margie Borra-Garske, Kevin R Campos, Scott Novick

Science· December 2019

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Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ.
Zahra Heidari, Ian M Chrisman, Michelle D Nemetchek, Scott J Novick, Anne-Laure Blayo

Nat Commun· December 2019

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Correction: HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.
Timothy S Strutzenberg, Ruben D Garcia-Ordonez, Scott J Novick, HaJeung Park, Mi Ra Chang

Elife· October 2019

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Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Hyeonwoo Kim, Christiane D Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Scott J Novick

Cell· July 2019

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HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.
Timothy S Strutzenberg, Ruben D Garcia-Ordonez, Scott J Novick, HaJeung Park, Mi Ra Chang

Elife· June 2019

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Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways.
Mi Ra Chang, Anthony Ciesla, Timothy S Strutzenberg, Scott J Novick, Yuanjun He

ACS Chem Biol· May 2019

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Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex.
Dipak N Patil, Erumbi S Rangarajan, Scott J Novick, Bruce D Pascal, Douglas J Kojetin

Elife· December 2018

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Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Hyeonwoo Kim, Christiane D Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Scott J Novick

Cell· December 2018

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HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.
Jie Zheng, Chen Wang, Mi Ra Chang, Swapnil C Devarkar, Brandon Schweibenz, Scott J Novick

Nat Commun· December 2018

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