Publications by authors named "Sebastian Andrei"

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Identification of a surface protein in the extracellular polymeric substances of seawater-adapted aerobic granular sludge.
Le Min Chen, Tessa Hofstra, Jelle Langedijk, Sebastian Andrei, Martin Pabst

Water Res· November 2025

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Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase.
Markus Ritzefeld, Leran Zhang, Zhangping Xiao, Sebastian A Andrei, Olivia Boyd

J Med Chem· January 2024

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IFNα primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization.
Blaž Andlovic, Geronimo Heilmann, Sabrina Ninck, Sebastian A Andrei, Federica Centorrino

Cell Chem Biol· June 2023

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Correction to "Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction".
Jakob S Pallesen, Claire C Munier, Francesco Bosica, Sebastian A Andrei, Karl Edman

J Med Chem· February 2023

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Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein-Protein Interaction.
Jakob S Pallesen, Claire C Munier, Francesco Bosica, Sebastian A Andrei, Karl Edman

J Med Chem· December 2022

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Evaluating Hedgehog Acyltransferase Activity and Inhibition Using the Acylation-coupled Lipophilic Induction of Polarization (Acyl-cLIP) Assay.
Sebastian A Andrei, Edward W Tate, Thomas Lanyon-Hogg

Methods Mol Biol· January 2022

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Structure, mechanism, and inhibition of Hedgehog acyltransferase.
Claire E Coupland, Sebastian A Andrei, T Bertie Ansell, Loic Carrique, Pramod Kumar

Mol Cell· December 2021

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Photochemical Probe Identification of a Small-Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)*.
Thomas Lanyon-Hogg, Markus Ritzefeld, Leran Zhang, Sebastian A Andrei, Balazs Pogranyi

Angew Chem Int Ed Engl· June 2021

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Photochemical Probe Identification of a Small-Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT).
Thomas Lanyon-Hogg, Markus Ritzefeld, Leran Zhang, Sebastian A Andrei, Balazs Pogranyi

Angew Chem Weinheim Bergstr Ger· June 2021

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Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers.
Eline Sijbesma, Kenneth K Hallenbeck, Sebastian A Andrei, Reanne R Rust, Joris M C Adriaans

ACS Med Chem Lett· June 2021

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Polypharmacological Perturbation of the 14-3-3 Adaptor Protein Interactome Stimulates Neurite Outgrowth.
Andrew Kaplan, Sebastian A Andrei, Anna van Regteren Altena, Tristan Simas, Sara L Banerjee

Cell Chem Biol· June 2020

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Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization.
Francesco Bosica, Sebastian A Andrei, João Filipe Neves, Peter Brandt, Anders Gunnarsson

Chemistry· June 2020

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Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry.
Alwin M Hartman, Walid A M Elgaher, Nathalie Hertrich, Sebastian A Andrei, Christian Ottmann

ACS Med Chem Lett· May 2020

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A study on the effect of synthetic α-to-β-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins.
Sebastian A Andrei, Vito Thijssen, Luc Brunsveld, Christian Ottmann, Lech-Gustav Milroy

Chem Commun (Camb)· December 2019

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Cooperativity basis for small-molecule stabilization of protein-protein interactions.
Pim J de Vink, Sebastian A Andrei, Yusuke Higuchi, Christian Ottmann, Lech-Gustav Milroy

Chem Sci· March 2019

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Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes.
Sebastian A Andrei, Femke A Meijer, João Filipe Neves, Luc Brunsveld, Isabelle Landrieu

ACS Chem Neurosci· November 2018

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Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14-3-3 Protein-Protein Interactions.
Sebastian A Andrei, Pim de Vink, Eline Sijbesma, Ling Han, Luc Brunsveld

Angew Chem Int Ed Engl· October 2018

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Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization.
Marcel Scheepstra, Sebastian A Andrei, Rens M J M de Vries, Femke A Meijer, Jian-Nong Ma

ACS Chem Neurosci· September 2017

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Stabilization of protein-protein interactions in drug discovery.
Sebastian A Andrei, Eline Sijbesma, Michael Hann, Jeremy Davis, Gavin O'Mahony

Expert Opin Drug Discov· September 2017

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Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.
Richard G Doveston, Ave Kuusk, Sebastian A Andrei, Seppe Leysen, Qing Cao

FEBS Lett· August 2017

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Designed Spiroketal Protein Modulation.
Marcel Scheepstra, Sebastian A Andrei, M Yagiz Unver, Anna K H Hirsch, Seppe Leysen

Angew Chem Int Ed Engl· May 2017

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