Publications by authors named "Sheri Booten"

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Inhibition of GCKIII kinases STK25 and MST3 mitigates organ lipotoxicity and enhances metabolic resilience under nutritional stress.
Emma Andersson, Xiangdong Gongye, Emmelie Cansby, Jingjing Zhang, Mara Caputo, Sheri Booten

BMC Med· September 2025

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Therapeutic Potential of STE20-Type Kinase STK25 Inhibition for the Prevention and Treatment of Metabolically Induced Hepatocellular Carcinoma.
Ying Xia, Mara Caputo, Emma Andersson, Bernice Asiedu, Jingjing Zhang, Sheri Booten

Cell Mol Gastroenterol Hepatol· June 2025

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Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice.
Ya-Wen Yang, Bibek Poudel, Julia Frederick, Poonam Dhillon, Rojesh Shrestha, Sheri L Booten

Mol Ther· July 2022

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Silencing of STE20-type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet-induced nonalcoholic fatty liver disease.
Mara Caputo, Yeshwant Kurhe, Sima Kumari, Emmelie Cansby, Manoj Amrutkar, Sheri L Booten

FASEB J· May 2021

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Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data.
Nicholas J Viney, Shuling Guo, Li-Jung Tai, Brenda F Baker, Mariam Aghajan, Sheri Booten

ESC Heart Fail· February 2021

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Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
Carla Casu, Mariateresa Pettinato, Alison Liu, Mariam Aghajan, Vania Lo Presti, Sheri Booten

Blood· October 2020

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Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease.
Emmelie Cansby, Esther Nuñez-Durán, Elin Magnusson, Manoj Amrutkar, Sheri L Booten

Cell Mol Gastroenterol Hepatol· June 2019

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Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
Mariam Aghajan, Sheri L Booten, Magnus Althage, Christopher E Hart, Anette Ericsson

JCI Insight· June 2019

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Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.
Esther Nuñez-Durán, Mariam Aghajan, Manoj Amrutkar, Silva Sütt, Emmelie Cansby, Sheri L Booten

Hepatol Commun· January 2018

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Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice.
Hichem Tasfaout, Suzie Buono, Shuling Guo, Christine Kretz, Nadia Messaddeq, Sheri Booten

Nat Commun· June 2017

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Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.
Karen L Posey, Francoise Coustry, Alka C Veerisetty, Mohammad Hossain, Danielle Gattis, Sheri Booten

Mol Ther· March 2017

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Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides.
Elizabeth J Ackermann, Shuling Guo, Merrill D Benson, Sheri Booten, Sue Freier

Amyloid· September 2016

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Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration.
Lulu Huang, Sagar S Damle, Sheri Booten, Priyam Singh, Mahyar Sabripour

PLoS One· May 2016

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Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes.
Thazha P Prakash, Jinghua Yu, Michael T Migawa, Garth A Kinberger, W Brad Wan, Sheri L Booten

J Med Chem· March 2016

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Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice.
Thazha P Prakash, Mark J Graham, Jinghua Yu, Rick Carty, Audrey Low, Sheri L Booten

Nucleic Acids Res· July 2014

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Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease.
Shuling Guo, Sheri L Booten, Andrew Watt, Luis Alvarado, Susan M Freier

Rare Dis· July 2014

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Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.
Shuling Guo, Sheri L Booten, Mariam Aghajan, Gene Hung, Chenguang Zhao

J Clin Invest· January 2014

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Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.
Shuling Guo, Carla Casu, Sara Gardenghi, Sheri Booten, Mariam Aghajan

J Clin Invest· April 2013

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Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein.
Richard G Lee, Wuxia Fu, Mark J Graham, Adam E Mullick, Donna Sipe, Sheri Booten

J Lipid Res· March 2013

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Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy.
Elizabeth J Ackermann, Shuling Guo, Sheri Booten, Luis Alvarado, Merrill Benson

Amyloid· June 2012

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Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.
Michael M Swarbrick, Peter J Havel, Arthur A Levin, Andrew A Bremer, Kimber L Stanhope, Sheri L Booten

Endocrinology· April 2009

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Reduction of JNK1 expression with antisense oligonucleotide improves adiposity in obese mice.
Xing Xian Yu, Susan F Murray, Lynnetta Watts, Sheri L Booten, Justin Tokorcheck

Am J Physiol Endocrinol Metab· August 2008

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Reduced adiposity and improved insulin sensitivity in obese mice with antisense suppression of 4E-BP2 expression.
Xing Xian Yu, Sanjay K Pandey, Sheri L Booten, Susan F Murray, Brett P Monia

Am J Physiol Endocrinol Metab· March 2008

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Specific reduction of hepatic glucose 6-phosphate transporter-1 ameliorates diabetes while avoiding complications of glycogen storage disease.
Kyle W Sloop, Aaron D Showalter, Amy L Cox, Julia X C Cao, Angela M Siesky, Sheri L Booten

J Biol Chem· June 2007

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miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.
Christine Esau, Scott Davis, Susan F Murray, Xing Xian Yu, Sanjay K Pandey, Sheri L Booten

Cell Metab· February 2006

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