Publications by authors named "Sidney D Nelson"

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Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.
Michael Kyriakides, Lea Maitre, Brendan D Stamper, Isaac Mohar, Terrance J Kavanagh, Sidney D Nelson

Arch Toxicol· December 2016

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Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6.
Isaac Mohar, Brendan D Stamper, Peter M Rademacher, Collin C White, Sidney D Nelson

Redox Biol· June 2015

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p53 Contributes to Differentiating Gene Expression Following Exposure to Acetaminophen and Its Less Hepatotoxic Regioisomer Both In Vitro and In Vivo.
Brendan D Stamper, Michael L Garcia, Duy Q Nguyen, Richard P Beyer, Theo K Bammler, Sidney D Nelson

Gene Regul Syst Bio· June 2015

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Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells.
Klarissa D Hardy, Michelle D Wahlin, Ioannis Papageorgiou, Jashvant D Unadkat, Allan E Rettie, Sidney D Nelson

Drug Metab Dispos· January 2014

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Comparative NMR-based metabonomic investigation of the metabolic phenotype associated with tienilic acid and tienilic acid isomer.
Muireann Coen, Peter M Rademacher, Wei Zou, Michael Scott, Patricia E Ganey, Sidney D Nelson

Chem Res Toxicol· November 2012

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Characterization of rat liver proteins adducted by reactive metabolites of menthofuran.
S Cyrus Khojasteh, Dylan P Hartley, Kevin A Ford, Hirdesh Uppal, Shimako Oishi, Sidney D Nelson

Chem Res Toxicol· November 2012

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Cross-linking mass spectrometry and mutagenesis confirm the functional importance of surface interactions between CYP3A4 and holo/apo cytochrome b(5).
Chunsheng Zhao, Qiuxia Gao, Arthur G Roberts, Scott A Shaffer, Catalin E Doneanu, Sidney D Nelson

Biochemistry· November 2012

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Covalent modification and time-dependent inhibition of human CYP2E1 by the meta-isomer of acetaminophen.
John P Harrelson, Brendan D Stamper, John D Chapman, David R Goodlett, Sidney D Nelson

Drug Metab Dispos· August 2012

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Interaction of lapatinib with cytochrome P450 3A5.
Eric Chun Yong Chan, Lee Sun New, Teck Beng Chua, Chun Wei Yap, Han Kiat Ho, Sidney D Nelson

Drug Metab Dispos· July 2012

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An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway.
Zhican Wang, Yvonne S Lin, Xi Emily Zheng, Tauri Senn, Takanori Hashizume, Sidney D Nelson

Mol Pharmacol· April 2012

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Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9.
Peter M Rademacher, Caleb M Woods, Qingbiao Huang, Grazyna D Szklarz, Sidney D Nelson

Chem Res Toxicol· April 2012

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Protein tyrosine nitration of mitochondrial carbamoyl phosphate synthetase 1 and its functional consequences.
Hideo Takakusa, Isaac Mohar, Terrance J Kavanagh, Edward J Kelly, Rüdiger Kaspera, Sidney D Nelson

Biochem Biophys Res Commun· March 2012

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The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.
Arthur G Roberts, Jing Yang, James R Halpert, Sidney D Nelson, Kenneth T Thummel

Biochemistry· December 2011

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Metabolic intermediate complex formation of human cytochrome P450 3A4 by lapatinib.
Hideo Takakusa, Michelle D Wahlin, Chunsheng Zhao, Kelsey L Hanson, Lee Sun New, Sidney D Nelson

Drug Metab Dispos· June 2011

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Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting.
Brendan D Stamper, Isaac Mohar, Terrance J Kavanagh, Sidney D Nelson

Chem Res Toxicol· April 2011

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Rearrangement reactions catalyzed by cytochrome P450s.
Paul R Ortiz de Montellano, Sidney D Nelson

Arch Biochem Biophys· March 2011

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Metabolism and toxicity of menthofuran in rat liver slices and in rats.
S Cyrus Khojasteh, Shimako Oishi, Sidney D Nelson

Chem Res Toxicol· November 2010

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Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib.
Woon Chien Teng, Jing Wen Oh, Lee Sun New, Michelle D Wahlin, Sidney D Nelson

Mol Pharmacol· October 2010

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Differential regulation of mitogen-activated protein kinase pathways by acetaminophen and its nonhepatotoxic regioisomer 3'-hydroxyacetanilide in TAMH cells.
Brendan D Stamper, Theo K Bammler, Richard P Beyer, Frederico M Farin, Sidney D Nelson

Toxicol Sci· July 2010

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Minimize the detection of false positives by the software program DetectShift for 18O-labeled cross-linked peptide analysis.
Quixia Gao, Song Xue, Scott A Shaffer, Catalin E Doneanu, David R Goodlett, Sidney D Nelson

Eur J Mass Spectrom (Chichester)· December 2008

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Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase.
Bo Wen, Kevin J Coe, Peter Rademacher, William L Fitch, Mario Monshouwer, Sidney D Nelson

Chem Res Toxicol· December 2008

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Multiple-ligand binding in CYP2A6: probing mechanisms of cytochrome P450 cooperativity by assessing substrate dynamics.
John P Harrelson, William M Atkins, Sidney D Nelson

Biochemistry· March 2008

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High-throughput screening and characterization of reactive metabolites using polarity switching of hybrid triple quadrupole linear ion trap mass spectrometry.
Bo Wen, Li Ma, Sidney D Nelson, Mingshe Zhu

Anal Chem· March 2008

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Cooperative binding of acetaminophen and caffeine within the P450 3A4 active site.
Michael D Cameron, Bo Wen, Arthur G Roberts, William M Atkins, A Patricia Campbell, Sidney D Nelson

Chem Res Toxicol· October 2007

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Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites.
Seva E Kostrubsky, Stephen C Strom, Ewa Ellis, Sidney D Nelson, Abdul E Mutlib

Chem Res Toxicol· October 2007

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