Publications by authors named "Stephen Baylin"

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Genomic Landscapes of Endometrioid and Mucinous Ovarian Cancers and Morphologically Similar Tumor Types.
Dorothy Hallberg, Alice C Eastman, Shashikant Koul, Daniel C Bruhm, Eniko Papp, Stephen B Baylin

Cancer Res Commun· November 2025

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Importance of De Novo Gene Evolution to Emerging Viral Threats: The ORF10 Strain-Restricted Orphan Gene of SARS-CoV-2 Promotes Pathogenesis.
Jeffrey A Haltom, Nidia S Trovao, Joseph W Guarnieri, Vincent Pan, Urminder Singh, Stephen B Baylin

Mol Biol Evol· October 2025

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Respiratory viral infections awaken metastatic breast cancer cells in lungs.
Shi B Chia, Bryan J Johnson, Junxiao Hu, Felipe Valença-Pereira, Marc Chadeau-Hyam, Stephen B Baylin

Nature· September 2025

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Epigenetic modulation of BARD1 to enhance anti-VEGF therapy.
Emine Bayraktar, Cristian Rodriguez-Aguayo, Elaine Stur, Sudhir Kumar, Lingegowda S Mangala, Stephen Baylin

Cell Rep Med· September 2025

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MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer.
Jina Park, Ying-Yu Chen, Jennie J Cao, Julia An, Ray-Whay Chiu Yen, Stephen B Baylin

Cell Rep· June 2025

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ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Lora Stojanovic, Rachel Abbotts, Kaushelendra Tripathi, Collin M Coon, Saranya Rajendran, Stephen B Baylin

Cancer Res· April 2025

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Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.
Jamie E Medina, Akshaya V Annapragada, Pien Lof, Sarah Short, Adrianna L Bartolomucci, Stephen B Baylin

Cancer Discov· January 2025

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Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy.
Wenjing Bai, Jinxin Xu, Wenbin Gu, Danyang Wang, Ying Cui, Stephen B Baylin

Nat Commun· January 2025

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Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Michael J Topper, Joseph W Guarnieri, Jeffrey A Haltom, Amy Chadburn, Henry Cope, Stephen B Baylin

Proc Natl Acad Sci U S A· December 2024

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UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation.
Rochelle L Tiedemann, Joel Hrit, Qian Du, Ashley K Wiseman, Hope E Eden, Stephen B Baylin

Nucleic Acids Res· December 2024

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Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS.
H Josh Jang, Guillermo Urrutia, Andreas Due Orskov, Hyeon Jin Kim, Seth A Nelson, Stephen B Baylin

bioRxiv· November 2024

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The Epigenetic Hallmarks of Cancer.
Manel Esteller, Mark A Dawson, Cigall Kadoch, Feyruz V Rassool, Peter A Jones, Stephen B Baylin

Cancer Discov· October 2024

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Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy.
Tae Gun Kang, Xin Lan, Tian Mi, Hongfeng Chen, Shanta Alli, Stephen Baylin

Science· October 2024

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sChemNET: a deep learning framework for predicting small molecules targeting microRNA function.
Diego Galeano, Imrat, Jeffrey Haltom, Chaylen Andolino, Aliza Yousey, Stephen B Baylin

Nat Commun· October 2024

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ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Lora Stojanovic, Rachel Abbotts, Kaushlendra Tripathi, Collin M Coon, Saranya Rajendran, Stephen B Baylin

bioRxiv· October 2024

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Human 8-oxoguanine glycosylase OGG1 binds nucleosome at the dsDNA ends and the super-helical locations.
Qinglong You, Xiang Feng, Yi Cai, Stephen B Baylin, Huilin Li

Commun Biol· September 2024

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Conserved epigenetic hallmarks of T cell aging during immunity and malignancy.
Tian Mi, Andrew G Soerens, Shanta Alli, Tae Gun Kang, Anoop Babu Vasandan, Stephen B Baylin

Nat Aging· August 2024

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DNA methylation and gene expression as determinants of genome-wide cell-free DNA fragmentation.
Michaël Noë, Dimitrios Mathios, Akshaya V Annapragada, Shashikant Koul, Zacharia H Foda, Stephen Baylin

Nat Commun· August 2024

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Space radiation damage rescued by inhibition of key spaceflight associated miRNAs.
J Tyson McDonald, JangKeun Kim, Lily Farmerie, Meghan L Johnson, Nidia S Trovao, Stephen Baylin

Nat Commun· June 2024

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A phase II study of guadecitabine combined with irinotecan vs regorafenib or TAS-102 in irinotecan-refractory metastatic colorectal cancer patients.
Valerie Lee, Rose Parkinson, Marianna Zahurak, Leslie Cope, Andrea Cercek, Stephen Baylin

Int J Cancer· May 2024

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Respiratory viral infection promotes the awakening and outgrowth of dormant metastatic breast cancer cells in lungs.
Shi B Chia, Bryan J Johnson, Junxiao Hu, Roel Vermeulen, Marc Chadeau-Hyam, Stephen B Baylin

Res Sq· April 2024

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Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling.
Alison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, Xiangqian Kong, Ying Cui, Stephen B Baylin

Sci Adv· March 2024

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Tissue-location-specific transcription programs drive tumor dependencies in colon cancer.
Lijing Yang, Lei Tu, Shilpa Bisht, Yiqing Mao, Daniel Petkovich, Stephen B Baylin

Nat Commun· February 2024

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UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation.
Rochelle L Tiedemann, Joel Hrit, Qian Du, Ashley K Wiseman, Hope E Eden, Stephen B Baylin

bioRxiv· February 2024

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SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.
Jeffrey Haltom, Nidia S Trovao, Joseph Guarnieri, Pan Vincent, Urminder Singh, Stephen B Baylin

medRxiv· November 2023

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