Publications by authors named "Steven R Magnuson"

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GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.
Alexander M Taylor, Chris Bailey, Lisa D Belmont, Robert Campbell, Nico Cantone, Steven R Magnuson

J Med Chem· August 2022

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GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.
Shumei Wang, Vickie Tsui, Terry D Crawford, James E Audia, Daniel J Burdick, Steven R Magnuson

J Med Chem· October 2018

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Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.
Terry D Crawford, Steffan Vartanian, Alexandre Côté, Steve Bellon, Martin Duplessis, Steven R Magnuson

Bioorg Med Chem Lett· August 2017

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GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).
Terry D Crawford, James E Audia, Steve Bellon, Daniel J Burdick, Archana Bommi-Reddy, Steven R Magnuson

ACS Med Chem Lett· July 2017

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Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition.
Srimoyee Ghosh, Alexander Taylor, Melissa Chin, Hon-Ren Huang, Andrew R Conery, Steven R Magnuson

J Biol Chem· June 2016

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Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.
Terry D Crawford, Vickie Tsui, E Megan Flynn, Shumei Wang, Alexander M Taylor, Steven R Magnuson

J Med Chem· June 2016

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Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.
Lan Wang, Mark Stanley, Jason W Boggs, Terry D Crawford, Brandon J Bravo, Steven R Magnuson

Bioorg Med Chem Lett· September 2014

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Discovery of selective 4-Amino-pyridopyrimidine inhibitors of MAP4K4 using fragment-based lead identification and optimization.
Terry D Crawford, Chudi O Ndubaku, Huifen Chen, Jason W Boggs, Brandon J Bravo, Steven R Magnuson

J Med Chem· April 2014

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Discovery of potent and selective pyrazolopyrimidine janus kinase 2 inhibitors.
Emily J Hanan, Anne van Abbema, Kathy Barrett, Wade S Blair, Jeff Blaney, Steven R Magnuson

J Med Chem· November 2012

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Prospects for kinase activity modulators in the treatment of diabetes and diabetic complications.
William H Bullock, Steven R Magnuson, Soongyu Choi, David E Gunn, Joachim Rudolph

Curr Top Med Chem· September 2002

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