Publications by authors named "Steven Xanthoudakis"

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Solid-phase analogue synthesis of caspase-3 inhibitors via palladium-catalyzed amination of 3-bromopyrazinones.
Elise Isabel, Renee Aspiotis, W Cameron Black, John Colucci, Réjean Fortin, Steven Xanthoudakis

Bioorg Med Chem Lett· March 2007

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Correlating the fractional inhibition of caspase-3 in NT2 cells with apoptotic markers using an active-caspase-3 enzyme-linked immunosorbent assay.
Paul Tawa, Andre Giroux, Erich Grimm, Yongxin Han, Donald W Nicholson, Steven Xanthoudakis

Anal Biochem· March 2006

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Gob-5 is not essential for mucus overproduction in preclinical murine models of allergic asthma.
Annette Robichaud, Stephanie A Tuck, Stacia Kargman, John Tam, Elizabeth Wong, Steven Xanthoudakis

Am J Respir Cell Mol Biol· September 2005

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Lipophilic versus hydrogen-bonding effect in P3 on potency and selectivity of valine aspartyl ketones as caspase 3 inhibitors.
Christophe Mellon, Reneé Aspiotis, Cameron W Black, Christopher I Bayly, Erich L Grimm, Steven Xanthoudakis

Bioorg Med Chem Lett· September 2005

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Solid phase synthesis of selective caspase-3 peptide inhibitors.
Erich L Grimm, Bruno Roy, Renee Aspiotis, Christopher I Bayly, Donald W Nicholson, Steven Xanthoudakis

Bioorg Med Chem· March 2004

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Neuroprotective effects of M826, a reversible caspase-3 inhibitor, in the rat malonate model of Huntington's disease.
Sylvie Toulmond, Keith Tang, Yves Bureau, Helen Ashdown, Sarah Degen, Steven Xanthoudakis

Br J Pharmacol· February 2004

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Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics.
Nathalie Méthot, JingQi Huang, Nathalie Coulombe, John P Vaillancourt, Dita Rasper, Steven Xanthoudakis

J Exp Med· January 2004

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Nicotinyl aspartyl ketones as inhibitors of caspase-3.
Elise Isabel, W Cameron Black, Christopher I Bayly, Erich L Grimm, Marc K Janes, Steven Xanthoudakis

Bioorg Med Chem Lett· July 2003

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NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.
Amir H Salehi, Steven Xanthoudakis, Philip A Barker

J Biol Chem· December 2002

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Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury.
Byung Hee Han, Daigen Xu, Junjeong Choi, Yongxin Han, Steven Xanthoudakis

J Biol Chem· August 2002

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Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.
François G Gervais, Roshni Singaraja, Steven Xanthoudakis, Claire-Anne Gutekunst, Blair R Leavitt

Nat Cell Biol· February 2002

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