Publications by authors named "Susan Lukas"

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The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.
Joerg Ermann, Mederbek Matmusaev, Emma K Haley, Clemens Braun, Felix Jost, Susan Lukas

Am J Physiol Gastrointest Liver Physiol· November 2021

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A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
Nuruddeen D Lewis, Lori A Patnaude, Josephine Pelletier, Donald J Souza, Susan M Lukas

PLoS One· October 2015

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No differences observed among multiple clinical S1P1 receptor agonists (functional antagonists) in S1P1 receptor down-regulation and degradation.
Susan Lukas, Lori Patnaude, Sokol Haxhinasto, Anthony Slavin, Melissa Hill-Drzewi

J Biomol Screen· March 2014

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The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function.
Thomas Noonan, Susan Lukas, Gregory W Peet, Josephine Pelletier, Mark Panzenbeck

Am J Clin Exp Immunol· July 2013

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Circulating monocytes are reduced by sphingosine-1-phosphate receptor modulators independently of S1P3.
Nuruddeen D Lewis, Sokol A Haxhinasto, Shawn M Anderson, Dimitria E Stefanopoulos, Steven E Fogal, Susan M Lukas

J Immunol· April 2013

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Assessment of biomarkers of cardiovascular risk among HIV type 1-infected adolescents: role of soluble vascular cell adhesion molecule as an early indicator of endothelial inflammation.
Salma S Syed, Rula S Balluz, Edmond K Kabagambe, William A Meyer, Susan Lukas

AIDS Res Hum Retroviruses· March 2013

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Bioluminescent method for assaying multiple semicarbazide-sensitive amine oxidase (SSAO) family members in both 96- and 384-well formats.
Gregory W Peet, Susan Lukas, Melissa Hill-Drzewi, Leslie Martin, Irina V Rybina

J Biomol Screen· October 2011

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The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
Jiang-Ping Wu, Ji Wang, Asitha Abeywardane, Denise Andersen, Michel Emmanuel, Susan Lukas

Bioorg Med Chem Lett· August 2007

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Discovery and characterization of a substrate selective p38alpha inhibitor.
Walter Davidson, Lee Frego, Gregory W Peet, Rachel R Kroe, Mark E Labadia, Susan M Lukas

Biochemistry· September 2004

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Catalysis and function of the p38 alpha.MK2a signaling complex.
Susan M Lukas, Rachel R Kroe, Jessi Wildeson, Gregory W Peet, Lee Frego

Biochemistry· August 2004

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Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.
Daniel R Goldberg, Tanja Butz, Mario G Cardozo, Robert J Eckner, Abdelhakim Hammach, Susan Lukas

J Med Chem· April 2003

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Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.
Roger J Snow, Mario G Cardozo, Tina M Morwick, Carl A Busacca, Yong Dong, Susan Lukas

J Med Chem· August 2002

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