Publications by authors named "Thomas Lanz"

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Generation of cynomolgus monkey capsid-specific positive control cells for IFNγ ELISpot assays for adeno-associated gene therapy applications.
Sandra Casinghino, Karrie Tartaro, Jessica Anderson, Ravindra C Kodihalli, Sophia G Lee, Thomas A Lanz

J Immunotoxicol· December 2025

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Correction: Longitudinal evaluation of serum neurofilament light levels in normal healthy volunteers: defining a threshold of concern.
Thomas A Lanz, Klemens Ruprecht, Christopher J Somps, Jens C Göpfert, Tony Kam-Thong

J Neurol· October 2025

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Longitudinal evaluation of serum neurofilament light levels in normal healthy volunteers: defining a threshold of concern.
Thomas A Lanz, Klemens Ruprecht, Christopher J Somps, Jens C Göpfert, Tony Kam-Thong

J Neurol· July 2025

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mRNA-LNPs induce immune activation and cytokine release in human whole blood assays across diverse health conditions.
Hong-My Nguyen, Kristin E Alexander, Mark Collinge, James C Hickey, Thomas A Lanz

Mol Ther· June 2025

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Transcriptomic and proteomic characterization of cell and protein biomarkers of checkpoint inhibitor-induced liver injury.
Changhua Ji, Steven Kumpf, Jessie Qian, Joel D Federspiel, Mark Sheehan, Thomas A Lanz

Cancer Immunol Immunother· May 2025

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Changes in Physical Activity, Heart Rate, and Sleep Measured by Activity Trackers During the COVID-19 Pandemic Across 34 Countries: Retrospective Analysis.
Bastien Wyatt, Nicolas Forstmann, Nolwenn Badier, Anne-Sophie Hamy, Quentin De Larochelambert, Thomas Lanz

J Med Internet Res· April 2025

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In vitro NIH3T3 mouse embryonic fibroblast cell model does not predict AAV2 or AAVdj-mediated cell transformation.
Luping Qiu, Steven W Kumpf, Elias M Oziolor, Mark Sheehan, James E Finley, Thomas A Lanz

Toxicol Appl Pharmacol· February 2025

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Comparison and cross-validation of long-read and short-read target-enrichment sequencing methods to assess AAV vector integration into host genome.
Mark Sheehan, Steven W Kumpf, Jessie Qian, David M Rubitski, Elias Oziolor, Thomas A Lanz

Mol Ther Methods Clin Dev· December 2024

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Single cell and TCR analysis of immune cells from AAV gene therapy-dosed Duchenne muscular dystrophy patients.
Michael R Emami, Mark A Brimble, Alejandro Espinoza, Jane Owens, Laurence O Whiteley, Thomas A Lanz

Mol Ther Methods Clin Dev· December 2024

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Improving the Assessment of Risk Factors Relevant to Potential Carcinogenicity of Gene Therapies: A Consensus Article.
Jan C Klapwijk, Alberto Del Rio Espinola, Silvana Libertini, Philippe Collin, Mick D Fellows, Thomas A Lanz

Hum Gene Ther· August 2024

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Perioperative Iron Deficiency in Patients Scheduled for Major Elective Surgeries: A French Prospective Multicenter Cross-Sectional Study.
Xavier Capdevila, Sigismond Lasocki, Alexis Duchalais, Jean-Christophe Rigal, Patrice Mertl, Thomas Lanz

Anesth Analg· August 2023

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Thymic lymphoma detection in RORγ knockout mice using 5-hydroxymethylcytosine profiling of circulating cell-free DNA.
Kelly A Fader, Mark M Gosink, Shuhua Xia, Thomas A Lanz, Charles Halsey

Toxicol Appl Pharmacol· August 2023

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A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6 T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation.
Wei Li, Kimberly K Crouse, Jennifer Alley, Richard K Frisbie, Susan C Fish, Thomas A Lanz

J Pharmacol Exp Ther· July 2023

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Comparing molecular and computational approaches for detecting viral integration of AAV gene therapy constructs.
Elias M Oziolor, Steven W Kumpf, Jessie Qian, Mark Gosink, Mark Sheehan, Thomas A Lanz

Mol Ther Methods Clin Dev· June 2023

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Modeling SARS-CoV-2: Comparative Pathology in Rhesus Macaque and Golden Syrian Hamster Models.
Shambhunath Choudhary, Isis Kanevsky, Soner Yildiz, Rani S Sellers, Kena A Swanson, Thomas A Lanz

Toxicol Pathol· April 2022

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Biodistribution and Tolerability of AAV-PHP.B-CBh- in Wistar Han Rats and Cynomolgus Macaques Reveal Different Toxicologic Profiles.
Xavier Palazzi, Ingrid D Pardo, Madhu P Sirivelu, Leah Newman, Steven W Kumpf, Thomas A Lanz

Hum Gene Ther· February 2022

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An Assessment of LRRK2 Serine 935 Phosphorylation in Human Peripheral Blood Mononuclear Cells in Idiopathic Parkinson's Disease and G2019S LRRK2 Cohorts.
Shalini Padmanabhan, Thomas A Lanz, Donal Gorman, Michele Wolfe, Alison Joyce

J Parkinsons Dis· July 2021

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An in vitro alveolar epithelial cell model recapitulates LRRK2 inhibitor-induced increases in lamellar body size observed in preclinical models.
Julie Harney, Piyush Bajaj, James E Finley, Anna K Kopec, Petra H Koza-Taylor, Thomas A Lanz

Toxicol In Vitro· February 2021

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Schizophrenia-associated SLC39A8 polymorphism is a loss-of-function allele altering glutamate receptor and innate immune signaling.
Wei Chou Tseng, Veronica Reinhart, Thomas A Lanz, Mark L Weber, Jincheng Pang

Transl Psychiatry· February 2021

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Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia.
Gun-Hoo Park, Haneul Noh, Zhicheng Shao, Peiyan Ni, Yiren Qin, Thomas A Lanz

Nat Neurosci· November 2020

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GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons.
Jonathan Garst-Orozco, Ruchi Malik, Thomas A Lanz, Mark L Weber, Hualin Xi

PLoS One· August 2020

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Author Correction: Design rules for light-emitting electrochemical cells delivering bright luminance at 27.5 percent external quantum efficiency.
Shi Tang, Andreas Sandström, Petter Lundberg, Thomas Lanz, Christian Larsen

Nat Commun· March 2020

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3'Pool-seq: an optimized cost-efficient and scalable method of whole-transcriptome gene expression profiling.
Gabriel Sholder, Thomas A Lanz, Robert Moccia, Jie Quan, Estel Aparicio-Prat

BMC Genomics· January 2020

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Optical analysis of light-emitting electrochemical cells.
E Mattias Lindh, Petter Lundberg, Thomas Lanz, Ludvig Edman

Sci Rep· July 2019

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Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus among matched tetrads of controls with subjects diagnosed with schizophrenia, bipolar or major depressive disorder.
Thomas A Lanz, Veronica Reinhart, Mark J Sheehan, Stacey J Sukoff Rizzo, Susan E Bove

Transl Psychiatry· May 2019

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