Publications by authors named "Toby Mathieson"

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Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination.
Katherine A McPhie, Diego Esposito, Jonathan Pettinger, Daniel Norman, Thilo Werner, Toby Mathieson

Chem Sci· June 2025

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Improved Proteomics-Based Drug Mechanism-of-Action Studies Using 16-Plex Isobaric Mass Tags.
Nico Zinn, Thilo Werner, Carola Doce, Toby Mathieson, Christine Boecker

J Proteome Res· March 2021

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Mass-spectrometry-based draft of the Arabidopsis proteome.
Julia Mergner, Martin Frejno, Markus List, Michael Papacek, Xia Chen, Toby Mathieson

Nature· March 2020

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Systematic analysis of protein turnover in primary cells.
Toby Mathieson, Holger Franken, Jan Kosinski, Nils Kurzawa, Nico Zinn

Nat Commun· February 2018

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Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics.
Gérard Joberty, Markus Boesche, Jack A Brown, Dirk Eberhard, Neil S Garton, Toby Mathieson

ACS Chem Biol· July 2016

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Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry.
Holger Franken, Toby Mathieson, Dorothee Childs, Gavain M A Sweetman, Thilo Werner

Nat Protoc· October 2015

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Mass-spectrometry-based draft of the human proteome.
Mathias Wilhelm, Judith Schlegl, Hannes Hahne, Amin Moghaddas Gholami, Marcus Lieberenz, Toby Mathieson

Nature· May 2014

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Ion coalescence of neutron encoded TMT 10-plex reporter ions.
Thilo Werner, Gavain Sweetman, Maria Fälth Savitski, Toby Mathieson, Marcus Bantscheff

Anal Chem· April 2014

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Measuring and managing ratio compression for accurate iTRAQ/TMT quantification.
Mikhail M Savitski, Toby Mathieson, Nico Zinn, Gavain Sweetman, Carola Doce

J Proteome Res· August 2013

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Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.
Michael D Urbaniak, Toby Mathieson, Marcus Bantscheff, Dirk Eberhard, Raffaella Grimaldi

ACS Chem Biol· November 2012

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A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.
Giovanna Bergamini, Kathryn Bell, Satoko Shimamura, Thilo Werner, Andrew Cansfield, Toby Mathieson

Nat Chem Biol· April 2012

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.
Marcus Bantscheff, Carsten Hopf, Mikhail M Savitski, Antje Dittmann, Paola Grandi, Toby Mathieson

Nat Biotechnol· March 2011

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Confident phosphorylation site localization using the Mascot Delta Score.
Mikhail M Savitski, Simone Lemeer, Markus Boesche, Manja Lang, Toby Mathieson

Mol Cell Proteomics· February 2011

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Evaluation of data analysis strategies for improved mass spectrometry-based phosphoproteomics.
Mikhail M Savitski, Arjen Scholten, Gavain Sweetman, Toby Mathieson, Marcus Bantscheff

Anal Chem· December 2010

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H-score, a mass accuracy driven rescoring approach for improved peptide identification in modification rich samples.
Mikhail M Savitski, Toby Mathieson, Isabelle Becher, Marcus Bantscheff

J Proteome Res· November 2010

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Targeted data acquisition for improved reproducibility and robustness of proteomic mass spectrometry assays.
Mikhail M Savitski, Frank Fischer, Toby Mathieson, Gavain Sweetman, Manja Lang

J Am Soc Mass Spectrom· October 2010

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Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.
Marcus Bantscheff, Dirk Eberhard, Yann Abraham, Sonja Bastuck, Markus Boesche, Toby Mathieson

Nat Biotechnol· September 2007

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