Publications by authors named "Travis Bainbridge"

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Effectorless Fc-fusion improves FLT3L drug-like properties for cancer immunotherapy combinations.
Jérémie Decalf, Evangeline Toy, Dongping He, Radhika Kenkre, Amy M Berkley, Travis W Bainbridge

EBioMedicine· August 2025

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Engineered IL-18 variants with half-life extension and improved stability for cancer immunotherapy.
Travis W Bainbridge, Lifen Wang, Marina Moskalenko, Robert Herrera, Maciej T Paluch

J Immunother Cancer· July 2025

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A single point mutation on FLT3L-Fc protein increases the risk of immunogenicity.
Dan Qin, Qui Phung, Patrick Wu, Zhaojun Yin, Sien Tam, Travis W Bainbridge

Front Immunol· May 2025

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A Minimal PBPK/PD Model with Expansion-Enhanced Target-Mediated Drug Disposition to Support a First-in-Human Clinical Study Design for a FLT3L-Fc Molecule.
Iraj Hosseini, Brett Fleisher, Jennifer Getz, Jérémie Decalf, Mandy Kwong, Travis W Bainbridge

Pharmaceutics· May 2024

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Nonclinical pharmacokinetics, pharmacodynamics and safety assessment of a FLT3L-Fc molecule for cancer immunotherapy.
Kai Connie Wu, Adeyemi O Adedeji, Tanja S Zabka, Iraj Hosseini, Radhika Kenkre, Travis W Bainbridge

Toxicol Appl Pharmacol· February 2024

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IL-1R1-dependent signaling coordinates epithelial regeneration in response to intestinal damage.
Christian B Cox, Elaine E Storm, Varun N Kapoor, Joseph Chavarria-Smith, David L Lin, Travis W Bainbridge

Sci Immunol· May 2021

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Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15 Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy.
Claudia X Dominguez, Sören Müller, Shilpa Keerthivasan, Hartmut Koeppen, Jeffrey Hung, Travis W Bainbridge

Cancer Discov· February 2020

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Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ.
William J Meilandt, Janice A Maloney, Jose Imperio, Guita Lalehzadeh, Tim Earr, Travis W Bainbridge

Alzheimers Res Ther· December 2019

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Adaptive adipose tissue stromal plasticity in response to cold stress and antibody-based metabolic therapy.
Joshua C Chang, Steffen Durinck, Mark Z Chen, Nadia Martinez-Martin, Jingli A Zhang, Travis W Bainbridge

Sci Rep· June 2019

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Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP).
Travis W Bainbridge, Diana Ronai Dunshee, Noelyn M Kljavin, Nicholas J Skelton, Junichiro Sonoda

Sci Rep· October 2017

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USP7 small-molecule inhibitors interfere with ubiquitin binding.
Lorna Kategaya, Paola Di Lello, Lionel Rougé, Richard Pastor, Kevin R Clark, Travis W Bainbridge

Nature· October 2017

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Effector-attenuating Substitutions That Maintain Antibody Stability and Reduce Toxicity in Mice.
Megan Lo, Hok Seon Kim, Raymond K Tong, Travis W Bainbridge, Jean-Michel Vernes

J Biol Chem· March 2017

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Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin.
Mark Ultsch, Bing Li, Till Maurer, Mary Mathieu, Oskar Adolfsson, Travis W Bainbridge

Sci Rep· December 2016

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Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Lionel Rougé, Travis W Bainbridge, Michael Kwok, Raymond Tong, Paola Di Lello

Structure· August 2016

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Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21.
Diana Ronai Dunshee, Travis W Bainbridge, Noelyn M Kljavin, Jose Zavala-Solorio, Amy C Schroeder

J Biol Chem· March 2016

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Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function.
Elaine E Storm, Steffen Durinck, Felipe de Sousa e Melo, Jarrod Tremayne, Noelyn Kljavin, Travis Bainbridge

Nature· January 2016

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Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.
Travis W Bainbridge, Venita I DeAlmeida, Anita Izrael-Tomasevic, Cécile Chalouni, Borlan Pan

PLoS One· November 2015

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Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.
Ganesh Kolumam, Mark Z Chen, Raymond Tong, Jose Zavala-Solorio, Lance Kates, Travis W Bainbridge

EBioMedicine· July 2015

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Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein.
Janice A Maloney, Travis Bainbridge, Amy Gustafson, Shuo Zhang, Roxanne Kyauk

J Biol Chem· November 2014

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Biochemical and biophysical properties of a putative hub protein expressed by vaccinia virus.
Nicole E Kay, Travis W Bainbridge, Richard C Condit, Michael R Bubb, Reuben E Judd

J Biol Chem· April 2013

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Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis.
Susan M D'Costa, Travis W Bainbridge, Sayuri E Kato, Cindy Prins, Karen Kelley

Virology· May 2010

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Marker rescue mapping of the combined Condit/Dales collection of temperature-sensitive vaccinia virus mutants.
Sayuri E M Kato, Nissin Moussatche, Susan M D'Costa, Travis W Bainbridge, Cindy Prins

Virology· May 2008

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Purification and properties of the vaccinia virus mRNA processing factor.
Susan M D'Costa, Travis W Bainbridge, Richard C Condit

J Biol Chem· February 2008

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