Publications by authors named "William Pitts"

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U.S. Army psychiatric and behavioral health challenges in future LSCO: A narrative review.
Sean L Wilkes, Christine L Wolfe, John Eric M Novosel-Lingat, William B Pitts, Rachel M Sullivan

Mil Psychol· December 2025

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The Division Psychiatrist in large-scale combat operations.
Sean L Wilkes, Kelly E MacDonald, Ramona A Deveney, William B Pitts

Mil Psychol· November 2025

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Comparison of percentile tables and algorithm-based calculators for classification of blood pressures in children and adolescents with obesity: A secondary analysis of a clinical trial.
William J Pitts, Tami L Cave, Alana Cavadino, Roman J Shypailo, Sarah E Maessen

J Paediatr Child Health· February 2023

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'Assisted self-proning' in a case of severe COVID-19 pneumonitis.
William Pitts, S Cais, E Simon, D Hunt

BMJ Mil Health· June 2022

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An innovative kinome platform to accelerate small-molecule inhibitor discovery and optimization from hits to leads.
Charu Chaudhry, Andrew Tebben, John S Tokarski, Robert Borzilleri, William J Pitts

Drug Discov Today· May 2021

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Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
Satheesh Nair, Sreekantha Ratna Kumar, Venkatram Reddy Paidi, Ramesh Sistla, Durgarao Kantheti, William J Pitts

ACS Med Chem Lett· July 2020

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Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage.
Amy C Hart, Lynn Abell, Junqing Guo, Michael E Mertzman, Ramesh Padmanabha, William J Pitts

ACS Med Chem Lett· March 2020

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Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.
Stephen T Wrobleski, Ryan Moslin, Shuqun Lin, Yanlei Zhang, Steven Spergel, William J Pitts

J Med Chem· October 2019

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Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis.
Steven H Spergel, Michael E Mertzman, James Kempson, Junqing Guo, Sylwia Stachura, William J Pitts

ACS Med Chem Lett· March 2019

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An Unexpected Circumstance: Acute Dystonic Reaction in the Setting of Clozapine Administration.
Alexander Morris Kaplan, William Bradly Pitts, Iqbal Ahmed

J Pharm Pract· February 2019

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Comparing a centralized institutional and student-run peer-assisted learning program in medicine.
Kevin G Buell, William Pitts, Matthew Edmondson, Ann Chu

Educ Health (Abingdon)· December 2018

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Dispersion and Burning Behavior of Hydrogen Released in a Full-Scale Residential Garage in the Presence and Absence of Conventional Automobiles - Supplemental Video Materials.
William M Pitts, Jiann C Yang, Kuldeep Prasad, Marco Fernandez

J Res Natl Inst Stand Technol· July 2018

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Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors.
Rajeev S Bhide, Alec Keon, Carolyn Weigelt, John S Sack, Robert J Schmidt, William J Pitts

Bioorg Med Chem Lett· November 2017

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Discovery of highly potent, selective, covalent inhibitors of JAK3.
James Kempson, Damaso Ovalle, Junqing Guo, Stephen T Wrobleski, Shuqun Lin, William J Pitts

Bioorg Med Chem Lett· October 2017

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Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.
John Hynes, Hong Wu, James Kempson, James J-W Duan, Zhonghui Lu, William J Pitts

Bioorg Med Chem Lett· July 2017

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Factors for Consideration in an Open-Flame Test for Assessing Fire Blocking Performance of Barrier Fabrics.
Shonali Nazaré, William M Pitts, John Shields, Rick Davis

Polymers (Basel)· September 2016

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Discovery and Structure-Activity Relationship (SAR) of a Series of Ethanolamine-Based Direct-Acting Agonists of Sphingosine-1-phosphate (S1P1).
John L Gilmore, James E Sheppeck, Scott H Watterson, Lauren Haque, Parag Mukhopadhyay, William J Pitts

J Med Chem· July 2016

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Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1).
Junqing Guo, Scott H Watterson, Steven H Spergel, James Kempson, Charles M Langevine, William J Pitts

Bioorg Med Chem Lett· May 2016

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Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P1): Discovery and SAR of a Novel Isoxazole Based Series.
Scott H Watterson, Junqing Guo, Steve H Spergel, Charles M Langevine, Robert V Moquin, William J Pitts

J Med Chem· March 2016

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Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5-d]pyrrolo[2,3-b]pyridine Inhibitors.
Amy C Hart, Gretchen M Schroeder, Honghe Wan, James Grebinski, Jennifer Inghrim, William J Pitts

ACS Med Chem Lett· August 2015

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Organic chemistry. Practical olefin hydroamination with nitroarenes.
Jinghan Gui, Chung-Mao Pan, Ying Jin, Tian Qin, Julian C Lo, William J Pitts

Science· May 2015

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Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.
John S Tokarski, Adriana Zupa-Fernandez, Jeffrey A Tredup, Kristen Pike, ChiehYing Chang, William J Pitts

J Biol Chem· April 2015

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Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors.
James J-W Duan, Zhonghui Lu, Bin Jiang, Bingwei V Yang, Lidia M Doweyko, William J Pitts

Bioorg Med Chem Lett· December 2014

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Rapid growing clay coatings to reduce the fire threat of furniture.
Yeon Seok Kim, Yu-Chin Li, William M Pitts, Martin Werrel, Rick D Davis

ACS Appl Mater Interfaces· February 2014

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Organic chemistry: Toolkit of reagents to aid drug discovery.
William J Pitts

Nature· December 2012

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