Publications by authors named "Yafan Lu"

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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late Ii), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.
Jeff A Zablocki, Elfatih Elzein, Xiaofen Li, Dmitry O Koltun, Eric Q Parkhill, Yafan Lu, Lufei Hu, Luiz Belardinelli

J Med Chem· October 2016

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Fragment-based discovery of nonpeptidic BACE-1 inhibitors using tethering.
Wenjin Yang, Raymond V Fucini, Bruce T Fahr, Mike Randal, Kenneth E Lind, Wanli Lu, Yafan Lu, Dennis Colussi

Biochemistry· June 2009

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Modifications of the isonipecotic acid fragment of SNS-032: analogs with improved permeability and lower efflux ratio.
Junfa Fan, Bruce Fahr, David Stockett, Erica Chan, Sravanthi Cheeti, Yafan Lu

Bioorg Med Chem Lett· December 2008

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A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties.
Ingrid C Choong, Iana Serafimova, Junfa Fan, David Stockett, Erica Chan, Yafan Lu

Bioorg Med Chem Lett· November 2008

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Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Raymond V Fucini, Emily J Hanan, Michael J Romanowski, Robert A Elling, Willard Lew, Yafan Lu

Bioorg Med Chem Lett· October 2008

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[Quality prediction model of greenhouse standard cut chrysanthemum based on light-temperature effect].
Zai-Qiang Yang, Wei-Hong Luo, Fa-Di Chen, Jun-Jie Gu, Xiang-Mao Li, Ya-Fan Lu

Ying Yong Sheng Tai Xue Bao· April 2007

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Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1.
Wenjin Yang, Wanli Lu, Yafan Lu, Min Zhong, Jian Sun

J Med Chem· February 2006

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