Publications by authors named "Youchao Deng"

Claim this Profile
I
Inhibition of -Specific DNA Adenine Methyltransferase CamA by Analogs of ‑Adenosyl‑l‑methionine.
Jujun Zhou, Youchao Deng, Dan Yu, Taraneh Hajian, Masoud Vedadi

ACS Omega· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A fused deep learning approach to transform drug repositioning.
Kun Li, Jiacai Yi, Qing Ye, Xixi Yang, Long Yu, YouChao Deng

Commun Chem· November 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DeepMetab: a comprehensive and mechanistically informed graph learning framework for end-to-end drug metabolism prediction.
Yiling Zhou, Dejun Jiang, Xiao Wei, Jiacai Yi, Yikun Wang, Youchao Deng

Chem Sci· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Uncertainty-Aware Deep Learning and Structural Feature Analysis for Reliable Nephrotoxicity Prediction.
Jian-Wang Liu, Ke-Yi Liu, You-Chao Deng, Shao-Hua Shi, Xiang-Zheng Fu

J Chem Inf Model· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Decoding the limits of deep learning in molecular docking for drug discovery.
Yue Li, Jiacai Yi, Hui Li, Kun Li, Fenghua Kang, Youchao Deng

Chem Sci· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and Biological Evaluation of Platensimycin Analogues with Improved Antimycobacterial Activity.
Guibin Liang, Enhe Bai, Zhoukang Zhuang, Jie Yang, Yu Li, Youchao Deng

J Med Chem· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterizations of Protein Arginine Deiminase 1 as a Substrate of NTMT1: Implications of Nα-Methylation in Protein Stability and Interaction.
Ying Meng, Zhouxian Li, Ming He, Quanqing Zhang, Youchao Deng

J Proteome Res· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Adenosine Analogue Library Reveals Insights into Active Sites of Protein Arginine Methyltransferases and Enables the Discovery of a Selective PRMT4 Inhibitor.
Youchao Deng, Eui-Jun Kim, Xiaosheng Song, Akshay S Kulkarni, Ryan X Zhu

J Med Chem· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Predicting novel targets with Bayesian machine learning by integrating multiple biological signatures.
Xiao Wei, Tingfei Zhu, Hiu Fung Yip, Xiangzheng Fu, Dejun Jiang, Youchao Deng

Chem Sci· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support.
Li Fu, Shaohua Shi, Jiacai Yi, Ningning Wang, Yuanhang He, Youchao Deng

Nucleic Acids Res· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
ChemFH: an integrated tool for screening frequent false positives in chemical biology and drug discovery.
Shaohua Shi, Li Fu, Jiacai Yi, Ziyi Yang, Xiaochen Zhang, Youchao Deng

Nucleic Acids Res· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhancing Molecular Property Prediction through Task-Oriented Transfer Learning: Integrating Universal Structural Insights and Domain-Specific Knowledge.
Yanjing Duan, Xixi Yang, Xiangxiang Zeng, Wenxuan Wang, Youchao Deng

J Med Chem· June 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhancing Multi-species Liver Microsomal Stability Prediction through Artificial Intelligence.
Teng-Zhi Long, De-Jun Jiang, Shao-Hua Shi, You-Chao Deng, Wen-Xuan Wang

J Chem Inf Model· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.
Youchao Deng, Xiaosheng Song, Iredia D Iyamu, Aiping Dong, Jinrong Min

Acta Pharm Sin B· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Specific DNA Adenine Methyltransferase.
Jujun Zhou, Youchao Deng, Iredia D Iyamu, John R Horton, Dan Yu

ACS Chem Biol· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition.
Youchao Deng, Guangping Dong, Ying Meng, Nicholas Noinaj, Rong Huang

J Med Chem· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
V
Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner.
Guangping Dong, Youchao Deng, Adam Yasgar, Ravi Yadav, Daniel Talley

J Med Chem· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a mammalian FASN inhibitor against xenografts of non-small cell lung cancer and melanoma.
Danfeng Cao, Jie Yang, Youchao Deng, Meng Su, Yeji Wang

Signal Transduct Target Ther· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Morphing Natural Product Platensimycin via Heck, Sonogashira, and One-Pot Sonogashira/Cycloaddition Reactions to Produce Antibiotics with In Vivo Activity.
Youchao Deng, Yuling Li, Zhongqing Wen, Claudia H Ruiz, Xiang Weng

Antibiotics (Basel)· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5.
Ayad A Al-Hamashi, Dongxing Chen, Youchao Deng, Guangping Dong, Rong Huang

Acta Pharm Sin B· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel Bisubstrate Inhibitors for Protein N-Terminal Acetyltransferase D.
Youchao Deng, Sunbin Deng, Yi-Hsun Ho, Sarah M Gardner, Zhi Huang

J Med Chem· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Semisynthesis and Biological Evaluation of Platencin Thioether Derivatives: Dual FabF and FabH Inhibitors against MRSA.
Yuling Li, Xiang Weng, Youchao Deng, Jian Pan, Saibin Zhu

ACS Med Chem Lett· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-based Discovery of Cell-Potent Peptidomimetic Inhibitors for Protein N-Terminal Methyltransferase 1.
Dongxing Chen, Guangping Dong, Youchao Deng, Nicholas Noinaj, Rong Huang

ACS Med Chem Lett· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis and biological Evaluation of Dual acetyl cholinesterase and beta-secretase inhibitors in treatment for alzheimer's Disease.
Youchao Deng, Yuren Jiang, Xiongjie Zhao, Jinlian Wang

Pak J Pharm Sci· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Late-Stage Functionalization of Platensimycin Leading to Multiple Analogues with Improved Antibacterial Activity in Vitro and in Vivo.
Youchao Deng, Xiang Weng, Yuling Li, Meng Su, Zhongqing Wen

J Med Chem· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis