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'Faith Healing' and 'Subtraction Anxiety' in Unblinded Trials of Procedures: Lessons from DEFER and FAME-2 for End Points in the ISCHEMIA Trial.
Christopher A Rajkumar, Sukhjinder S Nijjer, Graham D Cole, Rasha Al-Lamee, Darrel P Francis

Circ Cardiovasc Qual Outcomes· March 2018

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Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women-A Randomized Controlled Study.
Daniel König, Steffen Oesser, Stephan Scharla, Denise Zdzieblik, Albert Gollhofer

January 2018

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Core Outcome Set-STAndards for Development: The COS-STAD recommendations.
Jamie J Kirkham, Katherine Davis, Douglas G Altman, Jane M Blazeby, Mike Clarke

PLoS Med· November 2017

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Dietary soy and natto intake and cardiovascular disease mortality in Japanese adults: the Takayama study.
Chisato Nagata, Keiko Wada, Takashi Tamura, Kie Konishi, Yuko Goto

Am J Clin Nutr· February 2017

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Elevated Plasma Vitamin B12 Concentrations Are Independent Predictors of In-Hospital Mortality in Adult Patients at Nutritional Risk.
Silvia Cappello, Emanuele Cereda, Mariangela Rondanelli, Catherine Klersy, Barbara Cameletti

December 2016

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Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study.
Khalid A Jadoon, Stuart H Ratcliffe, David A Barrett, E Louise Thomas, Colin Stott

Diabetes Care· October 2016

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Effect of coenzyme Q10 plus nicotinamide adenine dinucleotide supplementation on maximum heart rate after exercise testing in chronic fatigue syndrome - A randomized, controlled, double-blind trial.
Jesus Castro-Marrero, Naia Sáez-Francàs, María Jose Segundo, Natalia Calvo, Mónica Faro

August 2016

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Cocoa Flavanol Supplementation Influences Skin Conditions of Photo-Aged Women: A 24-Week Double-Blind, Randomized, Controlled Trial.
Hyun-Sun Yoon, Jong Rhan Kim, Gyeong Yul Park, Jong-Eun Kim, Dong Hun Lee

J Nutr· January 2016

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Relations of change in plasma levels of LDL-C, non-HDL-C and apoB with risk reduction from statin therapy: a meta-analysis of randomized trials.
George Thanassoulis, Ken Williams, Keying Ye, Robert Brook, Patrick Couture

April 2014

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Altered placebo and drug labeling changes the outcome of episodic migraine attacks.
Slavenka Kam-Hansen, Moshe Jakubowski, John M Kelley, Irving Kirsch, David C Hoaglin

Sci Transl Med· January 2014

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The effects of inpatient exercise therapy on the length of hospital stay in stages I-III colon cancer patients: randomized controlled trial.
Ki-Yong Ahn, Hyuk Hur, Dong-Hyun Kim, Jihee Min, Duck Hyoun Jeong

Int J Colorectal Dis· May 2013

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A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis.
Binu Chandran, Ajay Goel

Phytother Res· November 2012

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Effect of music therapy on anxiety and depression in patients with Alzheimer's type dementia: randomised, controlled study.
Stéphane Guétin, F Portet, M C Picot, C Pommié, M Messaoudi

November 2009

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Relatives' experiences of end-of-life care and organ donation after controlled circulatory death: a national prospective multicenter study.
Matthieu Le Dorze, Anne Renet, Romain Barthélémy, Virginie Souppart, Nancy Kentish-Barnes

Crit Care· December 2025

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LenRuler: a rice-centric method for automated radicle length measurement with multicrop validation.
Jinfeng Zhao, Zeyu Hou, Hua Hua, Qianlong Nie, Yuqian Pang

Plant Phenomics· September 2025

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Surrogate Endpoints in Regulatory Decision-Making.
Linda J B Jeng, Jeffrey Siegel

Clin Transl Sci· December 2025

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Development of a core outcome set for the assessment of spasticity in adults: a study protocol.
Bridget Hill, Stephan Ashford, Hannah Barden, Lisa Shaw, Nick Waters

Trials· December 2025

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Application of Macroscopic On-Site Evaluation With Adjustable Light Source in EUS-FNA for Solid Pancreatic Masses.
Mengyi Deng, Dan Luo, Xianhao Tan, Xi Zhou, Ming Zhao

J Clin Gastroenterol· December 2025

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Idasanutlin in Combination with Chemotherapy or Venetoclax in Pediatric and Young Adult Patients with Relapsed/Refractory Solid Tumors (iMATRIX Idasa): Results of a Phase I/II, Multicenter, Multi-arm Study.
Alba Rubio-San-Simón, Lynley V Marshall, Francois Doz, Jaume Mora, Kevin Bielamowicz

Target Oncol· December 2025

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Group-Sequential Designs With an Externally-Driven Change of Primary Endpoint.
Amin Yarahmadi, Lori E Dodd, Peter Horby, Thomas Jaki, Nigel Stallard

Stat Med· December 2025

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Evaluating Food and Drug Administration approved gastrointestinal cancer drugs: clinical benefit and trial endpoints over the past two decades.
Fares Jamal, Oudai Sahvan, Pedro Luiz Serrano Uson Junior, Jeremy C Jones, Fang-Shu Ou

Oncologist· December 2025

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Real-world study to compare functional SYNTAX score versus anatomical SYNTAX score in influencing the treatment strategy for multivessel disease patients.
Nattawut Wongpraparut, Sivakumar Rathnavel, Mann Chandavimol, Chaiyasith Wongvipaporn, Davinder Singh Chadha

Sci Rep· December 2025

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The clinical and cost effectiveness of a conservative treatment pathway compared to appendicectomy in children with uncomplicated acute appendicitis: study protocol for a randomised controlled multi-centre open-label parallel-group non-inferiority trial (CONTRACT 2 trial) in the United Kingdom (UK).
Natalia Vadimovna Permyakova, Isabel C Reading, Young Bridget, Simon Eaton, Maria Chorozoglou

Trials· December 2025

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Progression-free survival as a surrogate for overall survival in gastro-esophageal cancer trials with immunotherapy: A meta-analysis.
Alberto Giovanni Leone, Fausto Petrelli, Samuel J Klempner, Elizabeth C Smyth, Raghav Sundar

Eur J Cancer· November 2025

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Graph Based, Adaptive, Multiarm, Multiple Endpoint, Two-Stage Designs.
Cyrus Mehta, Ajoy Mukhopadhyay, Martin Posch

Stat Med· December 2025

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A composite endpoint for systemic sclerosis-associated interstitial lung disease: association with mortality in two clinical trial cohorts.
Elizabeth R Volkmann, Holly Wilhalme, Sam Good, Grace Hyun J Kim, Jonathan Goldin

Respir Res· November 2025

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Maximal Lactate Steady State Prediction Using Two DMAX Methods in Horses Subjected to Treadmill-Graded Exercise Test.
Thayssa de Oliveira Littiere, Guilherme Barbosa da Costa, Nathali Adrielli Agassi de Sales, Júlia Ribeiro Garcia de Carvalho, Ivan Dario Martinez Rodriguez

J Anim Physiol Anim Nutr (Berl)· November 2025

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Redefining endpoints in heart failure clinical trials: the emerging role of wearable technologies in contemporary trial design.
Zahra Alawoad, Jesper Jensen, Morten Schou, Nouman Ahmed, Abdelrahman Attia

Heart Fail Rev· November 2025

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International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases: A second update.
Eva Oldenburger, Jane Jomy, Inmaculada Navarro-Domenech, Shing Fung Lee, Joanne M Van der Velden

Radiother Oncol· January 2026

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TRI·Fr eligibility criteria and outcome in real-world cohort of patients undergoing tricuspid transcatheter edge-to-edge repair.
Antonio Sisinni, Manuel Barreiro-Perez, Xavier Freixa, Dabit Arzamendi, Vanessa Moñivas

Int J Cardiol· February 2026

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Protocol for the development of a Core Outcome Set (COS) for reporting outcomes of clinical trials of anti-tuberculosis treatment in adults with pulmonary tuberculosis.
Rebecca Thomas, Nicola L Harman, Paula R Williamson, Laura Bonnett, Geraint R Davies

Trials· November 2025

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A Unified Approach to Covariate Adjustment for Survival Endpoints in Randomized Clinical Trials.
Zhiwei Zhang, Ya Wang, Dong Xi

Pharm Stat· November 2025

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Valid surrogate end-points in nonsmall cell lung cancer peri-operative systemic therapy trials: a systematic review.
Kohei Somekawa, Nobuyuki Horita, Satoshi Nagaoka, Yukihito Kajita, Suguru Muraoka

Eur Respir Rev· October 2025

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Surrogate Endpoints in Pivotal Clinical Trials for Drug Approval in Japan Compared to the United States.
Yuko Yamamoto, Harumi Kosaka, Hanami Nojiri, Hideki Maeda

Clin Transl Sci· November 2025

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A meta-analysis of albuminuria as a surrogate endpoint for kidney failure.
Hiddo J L Heerspink, Willem H Collier, Juhi Chaudhari, Shiyuan Miao, Hocine Tighiouart

Nat Med· November 2025

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Feasibility and acceptability of a parallel, two-arm randomized controlled trial to evaluate an online physical activity behavior counseling intervention for young adults diagnosed with cancer: a mixed-methods pilot study.
Jennifer Brunet, Jenson Price, Fiona Gillison, Martyn Standage, Monica Taljaard

Pilot Feasibility Stud· November 2025

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Evaluation of Event-Free Survival as a Surrogate Endpoint for Overall Survival in Muscle-Invasive Bladder Cancer Following Neoadjuvant Treatment: A Systematic Review and Meta-Analysis.
Cora N Sternberg, Patrick Squires, Yan Song, Aozhou Wu, Yipeng Gao

Oncol Ther· December 2025

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Simultaneous determination of macronutrient digestibility of two model foods: Introduction of an integrated preparation method harmonized with the INFOGEST protocol.
Judit Tormási, Eszter Benes, Éva Lengyel-Kónya, Mária Berki, Enikő Horváth-Szanics

Food Res Int· December 2025

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Avasopasem manganese treatment for severe oral mucositis from chemoradiotherapy for locally advanced head and neck cancer: phase 3 randomized controlled trial (ROMAN).
Carryn Anderson, Christopher M Lee, Joseph Randall Kelley, Gary V Walker, Neal E Dunlap

EClinicalMedicine· November 2025

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Research on the application of a high-throughput fully automated bacterial growth curve monitor for screening natural antibacterial compounds.
Shuangli Chen, Chengshuo Deng, Yixuan Liu, Xuanmei Huang, Xulong Chen

BMC Microbiol· October 2025

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