Publications by authors named "Alan Clarke"

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Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling.
Gabrielle H Ashton, Jennifer P Morton, Kevin Myant, Toby J Phesse, Rachel A Ridgway, Alan R Clarke

Dev Cell· June 2025

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Characterization of PLA Sheets Prepared by Stretching under Different Conditions: Influence of Reprocessing and Establishing Optimal Conditions.
Zaida Ortega, Paula Douglas, Paul R Hanna, Graham Garrett, Alan Clarke

Materials (Basel)· July 2023

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Spoligotype analysis of isolates from cattle and assessment of zoonotic TB transmission among individuals working in bovine TB-infected dairy farms in Ethiopia.
Gizat Almaw, Adane Mihret, Tamrat Abebe, Gobena Ameni, Balako Gumi, Alan Clarke

Zoonoses Public Health· September 2022

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3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
Luned M Badder, Andrew J Hollins, Bram Herpers, Kuan Yan, Kenneth B Ewan, Alan R Clarke

PLoS One· September 2020

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NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of Inactivation.
Cleberson J S Queiroz, Fei Song, Karen R Reed, Nadeem Al-Khafaji, Alan R Clarke

Front Oncol· August 2020

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Author Correction: Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
Zoë D Burke, Karen R Reed, Sheng-Wen Yeh, Valerie Meniel, Owen J Sansom, Alan R Clarke

Sci Rep· July 2020

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What are the clinical practice experiences of specialist and advanced paramedics working in emergency department roles? A qualitative study.
Alan Clarke

Br Paramed J· December 2019

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Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine.
Boris Y Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B Pearson, Douglas J Winton, Alan R Clarke

PLoS One· September 2019

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APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression.
Noha-Ehssan Mohamed, Trevor Hay, Karen R Reed, Matthew J Smalley, Alan R Clarke

BMC Cancer· July 2019

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What influences the effective practice and role optimisation of specialist/advanced paramedics working in emergency departments? A qualitative study.
Alan Clarke

Br Paramed J· June 2019

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Rapid activation of epithelial-mesenchymal transition drives PARP inhibitor resistance in -mutant mammary tumours.
Liliana D Ordonez, Trevor Hay, Robert McEwen, Urszula M Polanska, Adina Hughes, Alan R Clarke

Oncotarget· April 2019

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Correction for Muncan et al., "Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-".
Vanesa Muncan, Owen J Sansom, Leon Tertoolen, Toby J Phesse, Harry Begthel, Alan R Clarke

Mol Cell Biol· December 2018

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Better care: reducing length of stay and bed occupancy on an older adult psychiatric ward.
Katherine Adlington, Juliette Brown, Laura Ralph, Alan Clarke, Tim Bhoyroo

BMJ Open Qual· November 2018

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Oral Prion Neuroinvasion Occurs Independently of PrP Expression in the Gut Epithelium.
Alison Marshall, Barry M Bradford, Alan R Clarke, Jean C Manson, Neil A Mabbott

J Virol· October 2018

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TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.
Thomas G Bird, Miryam Müller, Luke Boulter, David F Vincent, Rachel A Ridgway, Mairi Clarke, Alan R Clarke

Sci Transl Med· August 2018

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Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.
Stephanie May, Heather Owen, Toby J Phesse, Kirsty R Greenow, Gareth-Rhys Jones, Alan R Clarke

J Pathol· July 2018

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Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway.
Zoë D Burke, Karen R Reed, Sheng-Wen Yeh, Valerie Meniel, Owen J Sansom, Alan R Clarke

Sci Rep· February 2018

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Subtle Deregulation of the Wnt-Signaling Pathway Through Loss of Apc2 Reduces the Fitness of Intestinal Stem Cells.
Madeleine A Young, Carl S Daly, Elaine Taylor, Rhiannon James, Alan Richard Clarke

Stem Cells· January 2018

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PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
Matthew T Jefferies, Adam C Cox, Boris Y Shorning, Valerie Meniel, David Griffiths, Alan R Clarke

J Pathol· December 2017

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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Inma M Berenjeno, Roberto Piñeiro, Sandra D Castillo, Wayne Pearce, Nicholas McGranahan, Alan Clarke

Nat Commun· November 2017

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Analysis of Fascin-1 in Relation to Gleason Risk Classification and Nuclear ETS-Related Gene Status of Human Prostate Carcinomas: An Immunohistochemical Study of Clinically Annotated Tumours From the Wales Cancer Bank.
Matthew T Jefferies, Christopher S Pope, Howard G Kynaston, Alan R Clarke, Richard M Martin

Biomark Cancer· May 2017

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Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma.
Elisabeth Naschberger, Andrea Liebl, Vera S Schellerer, Manuela Schütz, Nathalie Britzen-Laurent, Alan R Clarke

J Clin Invest· November 2016

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Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype.
Ravi K Deevi, Jane McClements, Karen D McCloskey, Aliya Fatehullah, Dorota Tkocz, Alan Clarke

Oncotarget· August 2016

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Secreted HMGB1 from Wnt activated intestinal cells is required to maintain a crypt progenitor phenotype.
Karen R Reed, Fei Song, Maddy A Young, Nurudeen Hassan, Daniel J Antoine, Alan R Clarke

Oncotarget· August 2016

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Epigenetic silencing of serine protease HTRA1 drives polyploidy.
Nina Schmidt, Inga Irle, Kamilla Ripkens, Vanda Lux, Jasmin Nelles, Alan R Clarke

BMC Cancer· July 2016

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