Publications by authors named "Basile Wicky"

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Atomically accurate de novo design of antibodies with RFdiffusion.
Nathaniel R Bennett, Joseph L Watson, Robert J Ragotte, Andrew J Borst, DéJenaé L See, Basile I M Wicky

Nature· January 2026

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Designed miniproteins potently inhibit and protect against MERS-CoV.
Robert J Ragotte, M Alejandra Tortorici, Nicholas J Catanzaro, Amin Addetia, Brian Coventry, Basile I M Wicky

Cell Rep· June 2025

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Atomically accurate de novo design of antibodies with RFdiffusion.
Nathaniel R Bennett, Joseph L Watson, Robert J Ragotte, Andrew J Borst, DéJenaé L See, Basile I M Wicky

bioRxiv· February 2025

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Massively parallel assessment of designed protein solution properties using mass spectrometry and peptide barcoding.
David Feldman, Jeremiah N Sims, Xinting Li, Richard Johnson, Stacey Gerben, Basile I M Wicky

bioRxiv· February 2025

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Design of pseudosymmetric protein hetero-oligomers.
Ryan D Kibler, Sangmin Lee, Madison A Kennedy, Basile I M Wicky, Stella M Lai

Nat Commun· December 2024

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Designed miniproteins potently inhibit and protect against MERS-CoV.
Robert J Ragotte, M Alejandra Tortorici, Nicholas J Catanzaro, Amin Addetia, Brian Coventry, Basile I M Wicky

bioRxiv· November 2024

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Improving Protein Expression, Stability, and Function with ProteinMPNN.
Kiera H Sumida, Reyes Núñez-Franco, Indrek Kalvet, Samuel J Pellock, Basile I M Wicky

J Am Chem Soc· January 2024

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De novo design of monomeric helical bundles for pH-controlled membrane lysis.
Nicolas Goldbach, Issa Benna, Basile I M Wicky, Jacob T Croft, Lauren Carter

Protein Sci· November 2023

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Hallucination of closed repeat proteins containing central pockets.
Linna An, Derrick R Hicks, Dmitri Zorine, Justas Dauparas, Basile I M Wicky

Nat Struct Mol Biol· November 2023

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De novo design of protein structure and function with RFdiffusion.
Joseph L Watson, David Juergens, Nathaniel R Bennett, Brian L Trippe, Jason Yim, Basile I M Wicky

Nature· August 2023

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Stepwise design of pseudosymmetric protein hetero-oligomers.
Ryan D Kibler, Sangmin Lee, Madison A Kennedy, Basile I M Wicky, Stella M Lai

bioRxiv· April 2023

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Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants.
Jason Z Zhang, Hsien-Wei Yeh, Alexandra C Walls, Basile I M Wicky, Kaitlin R Sprouse

Nat Biotechnol· September 2022

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Scaffolding protein functional sites using deep learning.
Jue Wang, Sidney Lisanza, David Juergens, Doug Tischer, Joseph L Watson, Basile I M Wicky

Science· July 2022

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Reconfigurable asymmetric protein assemblies through implicit negative design.
Danny D Sahtoe, Florian Praetorius, Alexis Courbet, Yang Hsia, Basile I M Wicky

Science· January 2022

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Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system.
Jason Z Zhang, Hsien-Wei Yeh, Alexandra C Walls, Basile I M Wicky, Kaiti Sprouse

bioRxiv· June 2021

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Protein sequence design by conformational landscape optimization.
Christoffer Norn, Basile I M Wicky, David Juergens, Sirui Liu, David Kim

Proc Natl Acad Sci U S A· March 2021

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Selective Affimers Recognise the BCL-2 Family Proteins BCL-x and MCL-1 through Noncanonical Structural Motifs*.
Jennifer A Miles, Fruzsina Hobor, Chi H Trinh, James Taylor, Christian Tiede, Basile I M Wicky

Chembiochem· January 2021

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De novo design of protein logic gates.
Zibo Chen, Ryan D Kibler, Andrew Hunt, Florian Busch, Jocelynn Pearl, Basile I M Wicky

Science· April 2020

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Extrinsic conditions influence the self-association and structure of IF, the regulatory protein of mitochondrial ATP synthase.
Vytaute Boreikaite, Basile I M Wicky, Ian N Watt, Jane Clarke, John E Walker

Proc Natl Acad Sci U S A· May 2019

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Stereodivergent Evolution of Artificial Enzymes for the Michael Reaction.
Xavier Garrabou, Duncan Stuart Macdonald, Basile I M Wicky, Donald Hilvert

Angew Chem Int Ed Engl· May 2018

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Affinity of IDPs to their targets is modulated by ion-specific changes in kinetics and residual structure.
Basile I M Wicky, Sarah L Shammas, Jane Clarke

Proc Natl Acad Sci U S A· September 2017

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Fast Knoevenagel Condensations Catalyzed by an Artificial Schiff-Base-Forming Enzyme.
Xavier Garrabou, Basile I M Wicky, Donald Hilvert

J Am Chem Soc· June 2016

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Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies.
Sarah L Shammas, Michael D Crabtree, Liza Dahal, Basile I M Wicky, Jane Clarke

J Biol Chem· March 2016

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Functional dissection of intersubunit interactions in the EspR virulence regulator of Mycobacterium tuberculosis.
Benjamin Blasco, Aleksandre Japaridze, Marco Stenta, Basile I M Wicky, Giovanni Dietler

J Bacteriol· May 2014

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Three bronze medals for Switzerland at the 45(th) International Chemistry Olympiad in Moscow, Russia.
Basile I M Wicky, Sebastian F Keller, Lucia D Meier, Michelle S Frei

Chimia (Aarau)· January 2014

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