Publications by authors named "Bernat Vidal"

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Prediction of the skin permeability of topical drugs using in silico and in vitro models.
Cristina Alonso, Víctor Carrer, Sonia Espinosa, Miriam Zanuy, Mònica Córdoba, Bernat Vidal

Eur J Pharm Sci· August 2019

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Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists.
Maria Antonia Buil, Marta Calbet, Marcos Castillo, Jordi Castro, Cristina Esteve, Bernat Vidal, Laura Vidal

Eur J Med Chem· May 2016

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A novel inhaled Syk inhibitor blocks mast cell degranulation and early asthmatic response.
Isabel Ramis, Raquel Otal, Cristina Carreño, Anna Domènech, Peter Eichhorn, Bernat Vidal

Pharmacol Res· September 2015

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Discovery of 7-azaindole derivatives as potent Orai inhibitors showing efficacy in a preclinical model of asthma.
Cristina Esteve, Jacob González, Sílvia Gual, Laura Vidal, Soledad Alzina, Bernat Vidal

Bioorg Med Chem Lett· March 2015

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Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists I.
Juan Antonio Alonso, Miriam Andrés, Mónica Bravo, Maria Antonia Buil, Marta Calbet, Bernat Vidal, Laura Vidal

Bioorg Med Chem Lett· November 2014

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Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists II: lead optimization.
Juan Antonio Alonso, Miriam Andrés, Mónica Bravo, Marta Calbet, Paul R Eastwood, Bernat Vidal, Laura Vidal

Bioorg Med Chem Lett· November 2014

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Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of bicyclic heteroaromatic acetic acids as potent CRTh2 antagonists III: the role of a hydrogen-bond acceptor in long receptor residence times.
Juan Antonio Alonso, Miriam Andrés, Mónica Bravo, Maria Antonia Buil, Marta Calbet, Bernat Vidal, Laura Vidal

Bioorg Med Chem Lett· November 2014

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Highly potent aminopyridines as Syk kinase inhibitors.
Marcos Castillo, Pilar Forns, Montse Erra, Marta Mir, Manel López, Bernat Vidal

Bioorg Med Chem Lett· September 2012

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Novel triazolopyridylbenzamides as potent and selective p38α inhibitors.
Josep Aiguadé, Cristina Balagué, Inés Carranco, Francisco Caturla, María Domínguez, Laura Vidal, Bernat Vidal

Bioorg Med Chem Lett· May 2012

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Pyrazine-based Syk kinase inhibitors.
Pilar Forns, Cristina Esteve, Lorena Taboada, Juan Antonio Alonso, Adelina Orellana, Bernat Vidal

Bioorg Med Chem Lett· April 2012

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1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase.
Wenceslao Lumeras, Laura Vidal, Bernat Vidal, Cristina Balagué, Adelina Orellana

J Med Chem· November 2011

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Indolin-2-one p38α inhibitors I: design, profiling and crystallographic binding mode.
Paul Eastwood, Jacob González, Elena Gómez, Bernat Vidal, Francisco Caturla

Bioorg Med Chem Lett· July 2011

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Discovery of LAS101057: A Potent, Selective, and Orally Efficacious A2B Adenosine Receptor Antagonist.
Paul Eastwood, Cristina Esteve, Jacob González, Silvia Fonquerna, Josep Aiguadé, Bernat Vidal

ACS Med Chem Lett· March 2011

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Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists.
María Isabel Nieto, María Carmen Balo, José Brea, Olga Caamaño, Franco Fernández, Bernat Vidal

Eur J Med Chem· July 2010

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Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists.
Paul Eastwood, Jacob Gonzalez, Sergio Paredes, Arsenio Nueda, Teresa Domenech, Bernat Vidal

Bioorg Med Chem Lett· March 2010

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Discovery of potent and selective bicyclic A(2B) adenosine receptor antagonists via bioisosteric amide replacement.
Paul Eastwood, Jacob Gonzalez, Sergio Paredes, Silvia Fonquerna, Arantxa Cardús, Bernat Vidal

Bioorg Med Chem Lett· March 2010

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Design, synthesis, and structure-activity relationships of aminopyridine N-oxides, a novel scaffold for the potent and selective inhibition of p38 mitogen activated protein kinase.
Wenceslao Lumeras, Francisco Caturla, Laura Vidal, Cristina Esteve, Cristina Balagué, Bernat Vidal

J Med Chem· September 2009

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1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
Franco Fernández, Olga Caamaño, M Isabel Nieto, Carmen López, Xerardo García-Mera, Bernat Vidal

Bioorg Med Chem· May 2009

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A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation.
Montserrat Buceta, Eduardo Domínguez, Marián Castro, José Brea, David Alvarez, Bernat Vidal

Biochem Pharmacol· October 2008

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1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.
Angela Stefanachi, Jose Manuel Brea, Maria Isabel Cadavid, Nuria B Centeno, Cristina Esteve, Bernat Vidal

Bioorg Med Chem· March 2008

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Synthesis, adenosine receptor binding and 3D-QSAR of 4-substituted 2-(2'-furyl)-1,2,4-triazolo[1,5-a]quinoxalines.
Ana Martínez, Hugo Gutiérrez-de-Terán, José Brea, Enrique Raviña, Maria Isabel Loza, Bernat Vidal

Bioorg Med Chem· February 2008

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Discovery and characterization of 4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine (LAS38096), a potent, selective, and efficacious A2B adenosine receptor antagonist.
Bernat Vidal, Arsenio Nueda, Cristina Esteve, Teresa Domenech, Sonia Benito

J Med Chem· May 2007

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New pyrrolopyrimidin-6-yl benzenesulfonamides: potent A2B adenosine receptor antagonists.
Cristina Esteve, Arsenio Nueda, José Luis Díaz, Jorge Beleta, Alvaro Cárdenas, Bernat Vidal

Bioorg Med Chem Lett· July 2006

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Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
Angelo Carotti, Maria Isabel Cadavid, Nuria B Centeno, Cristina Esteve, Maria Isabel Loza, Bernat Vidal

J Med Chem· January 2006

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