Publications by authors named "David Nickle"

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Improved Annotation of Asthma Gene Variants with Cell Type Deconvolution of Nasal and Lung Expression Quantitative Trait Loci.
Zaid W El-Husseini, Tatiana Karp, Andy Lan, Tessa E Gillett, Cancan Qi, David C Nickle

Am J Respir Cell Mol Biol· June 2025

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COPD susceptibility gene HHIP regulates repair genes in airway epithelial cells and repair within the epithelial-mesenchymal trophic unit.
Qing Chen, Marissa Wisman, Kingsley Okechukwu Nwozor, Don D Sin, Philippe Joubert, David C Nickle

Am J Physiol Lung Cell Mol Physiol· June 2025

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Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection.
Lela Kardava, James Lim, Clarisa M Buckner, Felipe Lopes de Assis, Xiaozhen Zhang, David C Nickle

Cell Rep· April 2025

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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, David C Nickle

Nat Genet· May 2024

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Age-associated differences in the human lung extracellular matrix.
Maunick Lefin Koloko Ngassie, Maaike De Vries, Theo Borghuis, Wim Timens, Don D Sin, David Nickle

Am J Physiol Lung Cell Mol Physiol· June 2023

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Genetic Associations and Architecture of Asthma-COPD Overlap.
Catherine John, Anna L Guyatt, Nick Shrine, Richard Packer, Thorunn A Olafsdottir, David Nickle

Chest· May 2022

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Rhinovirus and asthma: Challenges and opportunities.
Hector Ortega, David Nickle, Laura Carter

Rev Med Virol· July 2021

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Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19.
Ana I Hernández Cordero, Xuan Li, Stephen Milne, Chen Xi Yang, Yohan Bossé, David Nickle

Hum Genet· June 2021

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Global Landscape of Clostridioides Difficile Phylogeography, Antibiotic Susceptibility, and Toxin Polymorphisms by Post-Hoc Whole-Genome Sequencing from the MODIFY I/II Studies.
Hailong Zhao, David C Nickle, Zhen Zeng, Pierra Y T Law, Mark H Wilcox

Infect Dis Ther· June 2021

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Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank.
Kim Valette, Zhonglin Li, Valentin Bon-Baret, Arnaud Chignon, Jean-Christophe Bérubé, David C Nickle

Commun Biol· June 2021

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Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes.
Sébastien A Felt, Yan Sun, Agnieszka Jozwik, Allan Paras, Maximillian S Habibi, David Nickle

Nat Microbiol· May 2021

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Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic mechanisms.
Necola Guerrina, Hussein Traboulsi, Angela Rico de Souza, Yohan Bossé, Thomas H Thatcher, David C Nickle

FASEB J· March 2021

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Phenotypic and functional translation of IL33 genetics in asthma.
Maria E Ketelaar, Michael A Portelli, F Nicole Dijk, Nick Shrine, Alen Faiz, David C Nickle

J Allergy Clin Immunol· January 2021

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Gene expression network analysis provides potential targets against SARS-CoV-2.
Ana I Hernández Cordero, Xuan Li, Chen Xi Yang, Stephen Milne, Yohan Bossé, David Nickle

Sci Rep· December 2020

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Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection.
Maximillian S Habibi, Ryan S Thwaites, Meiping Chang, Agnieszka Jozwik, Allan Paras, David Nickle

Science· October 2020

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Genetic regulation of gene expression of MIF family members in lung tissue.
Laura Florez-Sampedro, Corry-Anke Brandsma, Maaike de Vries, Wim Timens, Rene Bults, David C Nickle

Sci Rep· October 2020

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Genetic Association Reveals Protection against Recurrence of Infection with Bezlotoxumab Treatment.
Judong Shen, Devan V Mehrotra, Mary Beth Dorr, Zhen Zeng, Junhua Li, David Nickle

mSphere· May 2020

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Protein-altering germline mutations implicate novel genes related to lung cancer development.
Xuemei Ji, Semanti Mukherjee, Maria Teresa Landi, Yohan Bosse, Philippe Joubert, David C Nickle

Nat Commun· May 2020

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Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium.
Michael A Portelli, F Nicole Dijk, Maria E Ketelaar, Nick Shrine, Jenny Hankinson, David C Nickle

JCI Insight· April 2020

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Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.
Richard J Allen, Beatriz Guillen-Guio, Justin M Oldham, Shwu-Fan Ma, Amy Dressen, David C Nickle

Am J Respir Crit Care Med· March 2020

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Letermovir Resistance Analysis in a Clinical Trial of Cytomegalovirus Prophylaxis for Hematopoietic Stem Cell Transplant Recipients.
Cameron M Douglas, Richard Barnard, Daniel Holder, Randi Leavitt, Diane Levitan, David Nickle

J Infect Dis· March 2020

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Differential lung tissue gene expression in males and females: implications for the susceptibility to develop COPD.
Maarten van den Berge, Corry-Anke Brandsma, Alen Faiz, Maaike de Vries, Senani N H Rathnayake, David C Nickle

Eur Respir J· July 2019

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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, David C Nickle

Nat Genet· June 2019

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New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, David C Nickle

Nat Genet· March 2019

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Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.
Nick Shrine, Michael A Portelli, Catherine John, María Soler Artigas, Neil Bennett, David C Nickle

Lancet Respir Med· January 2019

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