Publications by authors named "David Tess"

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Prediction of Drug-Drug Interactions for Highly Plasma Protein Bound Compounds.
David Tess, Makayla Harrison, Jian Lin, Rui Li, Li Di

AAPS J· December 2024

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Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model.
Brian D Adair, Conroy O Field, José L Alonso, Jian-Ping Xiong, Shi-Xian Deng, David A Tess

Nat Commun· October 2024

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Physiologically Based Pharmacokinetic Model of OATP1B Substrates with a Nonlinear Mixed Effect Approach: Estimating Empirical In Vitro-to-In Vivo Scaling Factors.
Rui Li, Emi Kimoto, Yi-An Bi, David Tess, Manthena V S Varma

Clin Pharmacokinet· August 2024

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Platelet integrin αIIbβ3 plays a key role in venous thrombogenesis in a mouse model.
Brian D Adair, Conroy O Field, José L Alonso, Jian-Ping Xiong, Shi-Xian Deng, David A Tess

bioRxiv· July 2024

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Characterization and Applications of Permeabilized Hepatocytes in Drug Discovery.
Sam Zhang, Christine C Orozco, Lloyd Wei Tat Tang, Jillian Racich, Anthony A Carlo, David Tess

AAPS J· March 2024

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Yi-An Bi, Samantha Jordan, Amanda King-Ahmad, Mark A West, Emi Yamaguchi, David A Tess

Drug Metab Dispos· February 2024

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Study of the ketohexokinase inhibitor PF-06835919 as a clinical cytochrome P450 3A inducer: Integrated use of oral midazolam and liquid biopsy.
Ruolun Qiu, Kari Fonseca, Arthur Bergman, Jian Lin, David Tess

Clin Transl Sci· January 2024

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The Comparison of Machine Learning and Mechanistic In Vitro-In Vivo Extrapolation Models for the Prediction of Human Intrinsic Clearance.
Christopher E Keefer, George Chang, Li Di, Nathaniel A Woody, David A Tess

Mol Pharm· November 2023

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Correction: A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics Applications.
Shiny Amala Priya Rajan, Jason Sherfey, Shivam Ohri, Lauren Nichols, J Tyler Smith, David Tess

AAPS J· November 2023

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A Novel Milli-fluidic Liver Tissue Chip with Continuous Recirculation for Predictive Pharmacokinetics Applications.
Shiny Amala Priya Rajan, Jason Sherfey, Shivam Ohri, Lauren Nichols, J Tyler Smith, David Tess

AAPS J· October 2023

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Relationship of binding-site occupancy, transthyretin stabilisation and disease modification in patients with tafamidis-treated transthyretin amyloid cardiomyopathy.
David A Tess, Tristan S Maurer, Zhenhong Li, Christine Bulawa, James Fleming

Amyloid· June 2023

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In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance of Human and Preclinical Species with Liver Microsomes and Hepatocytes.
David Tess, George C Chang, Christopher Keefer, Anthony Carlo, Rhys Jones

AAPS J· April 2023

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Addressing the Accuracy of Plasma Protein Binding Measurement for Highly Bound Compounds Using the Dilution Method.
Sangwoo Ryu, David Tess, Li Di

AAPS J· December 2022

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Effect of a Ketohexokinase Inhibitor (PF-06835919) on In Vivo OATP1B Activity: Integrative Risk Assessment Using Endogenous Biomarker and a Probe Drug.
David A Tess, Emi Kimoto, Amanda King-Ahmad, Manoli Vourvahis, A David Rodrigues

Clin Pharmacol Ther· September 2022

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In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species.
David A Tess, Sangwoo Ryu, Li Di

Pharm Res· July 2022

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Correction: In Vitro-In Vivo Extrapolation of Hepatic Clearance in Preclinical Species.
David A Tess, Sangwoo Ryu, Li Di

Pharm Res· July 2022

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Yan Weng, Kari R Fonseca, Yi-An Bi, Sumathy Mathialagan, Keith Riccardi, David A Tess

Drug Metab Dispos· July 2022

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Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey.
Carl Petersson, Xin Zhou, Joerg Berghausen, David Cebrian, Michael Davies, David Tess

AAPS J· July 2022

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A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
David A Griffith, David J Edmonds, Jean-Philippe Fortin, Amit S Kalgutkar, J Brent Kuzmiski, David A Tess

J Med Chem· June 2022

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Static and Dynamic Projections of Drug-Drug Interactions Caused by Cytochrome P450 3A Time-Dependent Inhibitors Measured in Human Liver Microsomes and Hepatocytes.
Elaine Tseng, Heather Eng, Jian Lin, Matthew A Cerny, David A Tess

Drug Metab Dispos· October 2021

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Evolving approaches on measurements and applications of intracellular free drug concentration and Kp in drug discovery.
Li Di, Keith Riccardi, David Tess

Expert Opin Drug Metab Toxicol· July 2021

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Evaluation of Prediction Accuracy for Volume of Distribution in Rat and Human Using In Vitro, In Vivo, PBPK and QSAR Methods.
Shibin Mathew, David Tess, Woodrow Burchett, George Chang, Nathaniel Woody

J Pharm Sci· April 2021

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Organic Anion-Transporting Polypeptide 1B1/1B3-Mediated Hepatic Uptake Determines the Pharmacokinetics of Large Lipophilic Acids: In Vitro-In Vivo Evaluation in Cynomolgus Monkey.
Heather Eng, Yi-An Bi, Mark A West, Sangwoo Ryu, Emi Yamaguchi, David A Tess

J Pharmacol Exp Ther· April 2021

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Effect of Human Plasma on Hepatic Uptake of Organic Anion-Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes.
Yi-An Bi, Sangwoo Ryu, David A Tess, A David Rodrigues, Manthena V S Varma

Drug Metab Dispos· January 2021

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Predicting the Human Hepatic Clearance of Acidic and Zwitterionic Drugs.
David A Tess, Heather Eng, Amit S Kalgutkar, John Litchfield, David J Edmonds

J Med Chem· October 2020

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