Publications by authors named "Dawn Stetsko"

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Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
Shailesh Dudhgaonkar, Sourabh Ranade, Jignesh Nagar, Siva Subramani, Durga Shiv Prasad, Dawn K Stetsko

J Immunol· February 2017

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B cells from African American lupus patients exhibit an activated phenotype.
Laurence C Menard, Sium Habte, Waldemar Gonsiorek, Deborah Lee, Dana Banas, Dawn Stetsko

JCI Insight· June 2016

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2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses.
Danya Liu, Scott M Krummey, I Raul Badell, Maylene Wagener, Lumelle A Schneeweis, Dawn K Stetsko

J Exp Med· February 2014

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A monovalent anti-human CD28 domain antibody antagonist: preclinical efficacy and safety.
Suzanne J Suchard, Patricia M Davis, Selena Kansal, Dawn K Stetsko, Ruth Brosius

J Immunol· November 2013

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Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521).
Scott H Watterson, Zili Xiao, Dharmpal S Dodd, David R Tortolani, Wayne Vaccaro, Dawn K Stetsko

J Med Chem· May 2010

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An LFA-1 (alphaLbeta2) small-molecule antagonist reduces inflammation and joint destruction in murine models of arthritis.
Suzanne J Suchard, Dawn K Stetsko, Patricia M Davis, Stacey Skala, Dominique Potin

J Immunol· April 2010

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IL-12 and IL-23 in health and disease.
Dawn Stetsko, Daniel N Sauder

Expert Rev Clin Immunol· May 2008

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Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction.
Patricia M Davis, Steven G Nadler, Dawn K Stetsko, Suzanne J Suchard

Clin Immunol· January 2008

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Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold.
Dharmpal S Dodd, Steven Sheriff, ChiehYing J Chang, Dawn K Stetsko, Linda M Phillips

Bioorg Med Chem Lett· April 2007

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Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1.
Dominique Potin, Michele Launay, Francoise Monatlik, Patrice Malabre, Maud Fabreguettes, Dawn K Stetsko

J Med Chem· November 2006

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De novo design, synthesis, and in vitro activity of LFA-1 antagonists based on a bicyclic[5.5]hydantoin scaffold.
Dominique Potin, Michele Launay, Eric Nicolai, Maud Fabreguette, Patrice Malabre, Dawn K Stetsko

Bioorg Med Chem Lett· February 2005

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