Publications by authors named "Ingo Gorr"

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Perfusion process with tangential flow filtration for oncolytic VSV-GP production.
Orsolya Hamusics, Anja Wittmann, Katrin Hasler, Sabrina Müller, Daniel Birk, Ingo H Gorr

Front Bioeng Biotechnol· May 2025

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Accelerated CMC workflows to enable speed to clinic in the COVID-19 era: A multi-company view from the biopharmaceutical industry.
Matthew F Higgins, Nicholas Abu-Absi, Elena Gontarz, Ingo H Gorr, Klaus Kaiser

Biotechnol Prog· March 2023

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Applying intensified design of experiments to mammalian cell culture processes.
Verena Nold, Lisa Junghans, Lorenzo Bisgen, Raphael Drerup, Beate Presser, Ingo Gorr

Eng Life Sci· December 2022

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Structural analysis of random transgene integration in CHO manufacturing cell lines by targeted sequencing.
Anna Stadermann, Martin Gamer, Jürgen Fieder, Benjamin Lindner, Steffen Fehrmann, Ingo H Gorr

Biotechnol Bioeng· March 2022

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Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network.
Elke Prade, Anne Zeck, Fabian Stiefel, Andreas Unsoeld, David Mentrup, Ingo H Gorr

Biotechnol Bioeng· March 2021

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Pre-stage perfusion and ultra-high seeding cell density in CHO fed-batch culture: a case study for process intensification guided by systems biotechnology.
Lisa Stepper, Florian Alois Filser, Simon Fischer, Jochen Schaub, Ingo Gorr

Bioprocess Biosyst Eng· August 2020

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Unraveling what makes a monoclonal antibody difficult-to-express: From intracellular accumulation to incomplete folding and degradation via ERAD.
Sven Mathias, Anna Wippermann, Nadja Raab, Nikolas Zeh, René Handrick, Ingo Gorr

Biotechnol Bioeng· January 2020

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Reduction of IL-2 fragmentation during manufacturing of a novel immunocytokine by DoE process optimization.
Alina Schneider, Ingo H Gorr, Vincent Larraillet, Timo Frensing, Oliver Popp

Biotechnol Bioeng· October 2019

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Visualisation of intracellular production bottlenecks in suspension-adapted CHO cells producing complex biopharmaceuticals using fluorescence microscopy.
Sven Mathias, Simon Fischer, René Handrick, Jürgen Fieder, Patrick Schulz, Ingo Gorr

J Biotechnol· April 2018

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miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.
Simon Fischer, Kim F Marquart, Lisa A Pieper, Juergen Fieder, Martin Gamer, Ingo Gorr

Biotechnol Bioeng· July 2017

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A single-step FACS sorting strategy in conjunction with fluorescent vital dye imaging efficiently assures clonality of biopharmaceutical production cell lines.
Jürgen Fieder, Patrick Schulz, Ingo Gorr, Harald Bradl, Till Wenger

Biotechnol J· June 2017

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Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.
Christian Klein, Inja Waldhauer, Valeria G Nicolini, Anne Freimoser-Grundschober, Tapan Nayak, Ingo H Gorr

Oncoimmunology· January 2017

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Molecular polygamy: The promiscuity of l-phenylalanyl-tRNA-synthetase triggers misincorporation of meta- and ortho-tyrosine in monoclonal antibodies expressed by Chinese hamster ovary cells.
Oliver Popp, Vincent Larraillet, Hubert Kettenberger, Ingo H Gorr, Maximiliane Hilger

Biotechnol Bioeng· June 2015

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Modulation of mesenchymal stromal cell characteristics by microcarrier culture in bioreactors.
Julia Hupfeld, Ingo H Gorr, Christian Schwald, Nicola Beaucamp, Kornelius Wiechmann

Biotechnol Bioeng· November 2014

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Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy.
Carola H Ries, Michael A Cannarile, Sabine Hoves, Jörg Benz, Katharina Wartha, Ingo H Gorr

Cancer Cell· June 2014

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Low level sequence variant analysis of recombinant proteins: an optimized approach.
Anne Zeck, Jörg Thomas Regula, Vincent Larraillet, Björn Mautz, Oliver Popp, Ingo H Gorr

PLoS One· April 2013

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Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes.
Ingo H Gorr, Alexandra Reis, Dominik Boos, Martin Wühr, Suzanne Madgwick

Nat Cell Biol· September 2006

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Anaphase topsy-turvy: Cdk1 a securin, separase a CKI.
Olaf Stemmann, Ingo H Gorr, Dominik Boos

Cell Cycle· January 2006

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Mutual inhibition of separase and Cdk1 by two-step complex formation.
Ingo H Gorr, Dominik Boos, Olaf Stemmann

Mol Cell· July 2005

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Rephrasing anaphase: separase FEARs shugoshin.
Olaf Stemmann, Dominik Boos, Ingo H Gorr

Chromosoma· March 2005

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