Publications by authors named "JB Carroll"

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Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.
Ella W Mathews, Sydney R Coffey, Annette Gärtner, Jillian Belgrad, Robert M Bragg, Jeffrey B Carroll

Nat Commun· November 2025

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Huntingtin knockdown dysregulates autophagic degradation of Apolipoprotein E.
Gianna M Fote, Nicolette R McClure, Robert M Bragg, Jharrayne McKnight, Leslie M Thompson, Jeffrey B Carroll

J Huntingtons Dis· October 2025

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Altered huntingtin-chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease.
Jocelynn R Pearl, Amol C Shetty, Jeffrey P Cantle, Dani E Bergey, Robert M Bragg, Jeffrey B Carroll

Dis Model Mech· May 2025

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In vivo CRISPR-Cas9 genome editing in mice identifies genetic modifiers of somatic CAG repeat instability in Huntington's disease.
Ricardo Mouro Pinto, Ryan Murtha, António Azevedo, Cameron Douglas, Marina Kovalenko, Jeffrey B Carroll

Nat Genet· February 2025

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Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.
Ella W Mathews, Sydney R Coffey, Annette Gärtner, Jillian Belgrad, Robert M Bragg, Jeffrey B Carroll

bioRxiv· November 2024

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Global huntingtin knockout in adult mice leads to fatal neurodegeneration that spares the pancreas.
Robert M Bragg, Ella W Mathews, Andrea Grindeland, Jeffrey P Cantle, David Howland, Jeffrey B Carroll

Life Sci Alliance· September 2024

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Identification of genetic modifiers of Huntington's disease somatic CAG repeat instability by in vivo CRISPR-Cas9 genome editing.
Ricardo Mouro Pinto, Ryan Murtha, António Azevedo, Cameron Douglas, Marina Kovalenko, Jeffrey B Carroll

bioRxiv· June 2024

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Establishing resources and increasing awareness to advance research on Dentatorubral-pallidoluysian atrophy toward a treatment: a patient organization perspective.
Silvia Prades, Andrea Compton, Jeffrey B Carroll

Ther Adv Rare Dis· May 2024

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Understanding dentatorubral-pallidoluysian atrophy (DRPLA) symptoms and impacts on daily life: a qualitative interview study with patients and caregivers.
Marielle G Contesse, Rebecca J Woods, Mindy Leffler, Silvia Prades, Julie Greenfield, Jeffrey B Carroll

Ther Adv Rare Dis· May 2024

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Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.
Robert M Bragg, Sydney R Coffey, Jeffrey P Cantle, Shikai Hu, Sucha Singh, Jeffrey B Carroll

Life Sci Alliance· November 2023

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Personalized antisense oligonucleotides 'for free, for life' - the n-Lorem Foundation.
Joseph G Gleeson, C Frank Bennett, Jeffrey B Carroll, Tracy Cole, Julie Douville

Nat Med· June 2023

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Huntingtin loss in hepatocytes is associated with altered metabolism, adhesion, and liver zonation.
Robert M Bragg, Sydney R Coffey, Jeffrey P Cantle, Shikai Hu, Sucha Singh, Jeffrey B Carroll

bioRxiv· June 2023

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Microglial heterogeneity and complement component 3 elimination within emerging multisensory midbrain compartments during an early critical period.
Julianne B Carroll, Shaida Hamidi, Mark L Gabriele

Front Neurosci· January 2023

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Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models.
Xiaonan Zhao, Cassandra McHugh, Sydney R Coffey, Diego Antonio Jimenez, Elizabeth Adams, Jeffrey B Carroll

Dis Model Mech· May 2022

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Compromised fractalkine signaling delays microglial occupancy of emerging modules in the multisensory midbrain.
Cooper A Brett, Julianne B Carroll, Mark L Gabriele

Glia· April 2022

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Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease.
Todd M Greco, Christopher Secker, Eduardo Silva Ramos, Joel D Federspiel, Jeh-Ping Liu, Jeffrey B Carroll

Cell Syst· April 2022

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Segregation of Multimodal Inputs Into Discrete Midbrain Compartments During an Early Critical Period.
Jacob M Weakley, Erin K Kavusak, Julianne B Carroll, Mark L Gabriele

Front Neural Circuits· April 2022

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Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
Rachel J Harding, Justin C Deme, Johannes F Hevler, Sem Tamara, Alexander Lemak, Jeffrey B Carroll

Commun Biol· December 2021

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Single-Nucleus RNA-Seq Reveals Dysregulation of Striatal Cell Identity Due to Huntington's Disease Mutations.
Sonia Malaiya, Marcia Cortes-Gutierrez, Brian R Herb, Sydney R Coffey, Samuel R W Legg, Jeffrey B Carroll

J Neurosci· June 2021

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Registry of Compartmental Ephrin-B3 Guidance Patterns With Respect to Emerging Multimodal Midbrain Maps.
Jeremiah P C Stinson, Cooper A Brett, Julianne B Carroll, Mark L Gabriele

Front Neuroanat· March 2021

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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Eric Vallabh Minikel, Hien T Zhao, Jason Le, Jill O'Moore, Rose Pitstick, Jeffrey B Carroll

Nucleic Acids Res· November 2020

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HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.
Marina Kovalenko, Austen Milnerwood, James Giordano, Jason St Claire, Jolene R Guide, Jeffrey B Carroll

J Huntingtons Dis· October 2019

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Antisense oligonucleotides extend survival of prion-infected mice.
Gregory J Raymond, Hien Tran Zhao, Brent Race, Lynne D Raymond, Katie Williams, Jeffrey B Carroll

JCI Insight· July 2019

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Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.
Seth A Ament, Jocelynn R Pearl, Jeffrey P Cantle, Robert M Bragg, Peter J Skene, Jeffrey B Carroll

Mol Syst Biol· March 2018

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Early Detection of Apathetic Phenotypes in Huntington's Disease Knock-in Mice Using Open Source Tools.
Shawn Minnig, Robert M Bragg, Hardeep S Tiwana, Wes T Solem, William S Hovander, Jeffrey B Carroll

Sci Rep· February 2018

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