Publications by authors named "John Hickman"

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TOpCLASS Expert Consensus Classification of Perianal Fistulising Crohn's Disease: A Real-world Application in a Serial Fistula MRI Cohort.
Matthew K Schroeder, Suha Abushamma, Alvin T George, Balakrishna Ravella, John Hickman

J Crohns Colitis· September 2024

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Geldof Expert Consensus Classification of Perianal Fistulizing Crohn's Disease: A Real-World Application in a Serial Fistula MRI Cohort.
Matthew Schroeder, Suha Abushamma, Alvin T George, Ravella Balakrishna, John Hickman

medRxiv· February 2024

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Precision Medicine for Childhood Cancer: Current Limitations and Future Perspectives.
Martin G McCabe, Birgit Geoerger, Louis Chesler, Darren Hargrave, D Williams Parsons, John A Hickman

JCO Precis Oncol· January 2024

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Costs and Causes of Oncology Drug Attrition With the Example of Insulin-Like Growth Factor-1 Receptor Inhibitors.
Valerie Jentzsch, Leeza Osipenko, Jack W Scannell, John A Hickman

JAMA Netw Open· July 2023

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Predictive validity in drug discovery: what it is, why it matters and how to improve it.
Jack W Scannell, James Bosley, John A Hickman, Gerard R Dawson, Hubert Truebel

Nat Rev Drug Discov· December 2022

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Practical strategies for delivering airway training in the COVID-19 era.
John Hickman, Alistair F McNarry, Fiona E Kelly

Br J Anaesth· August 2021

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The European Union and personalised cancer medicine.
John A Hickman, Ian F Tannock, Lydie Meheus, Lisa Hutchinson

Eur J Cancer· June 2021

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Knowing your tumour?
Ian F Tannock, John A Hickman

Lancet Oncol· June 2020

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Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
James B Murray, James Davidson, Ijen Chen, Ben Davis, Pawel Dokurno, John Hickman

ACS Omega· May 2019

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Superficial branch of the radial nerve injury: A case for conscious perioperative arterial cannulation.
John Hickman, Ahmed Chekairi

J Perioper Pract· April 2018

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S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Patrick Casara, James Davidson, Audrey Claperon, Gaëtane Le Toumelin-Braizat, Meike Vogler, John A Hickman

Oncotarget· April 2018

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Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project.
Ronald de Hoogt, Marta F Estrada, Suzana Vidic, Emma J Davies, Annika Osswald, John Hickman

Sci Data· November 2017

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Limits to Precision Cancer Medicine.
Ian F Tannock, John A Hickman

N Engl J Med· January 2017

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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, John A Hickman

Nature· October 2016

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An overview of the necessary thymic contributions to tolerance in transplantation.
Joseph R Scalea, John B Hickman, Daniel J Moore, Kenneth L Brayman

Clin Immunol· October 2016

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Limits to Personalized Cancer Medicine.
Ian F Tannock, John A Hickman

N Engl J Med· September 2016

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Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices.
Emma J Davies, Meng Dong, Matthias Gutekunst, Katja Närhi, Hanneke J A A van Zoggel, John A Hickman

Sci Rep· December 2015

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Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo.
John A Hickman, Ralph Graeser, Ronald de Hoogt, Suzana Vidic, Catarina Brito

Biotechnol J· September 2014

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S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Mike F Burbridge, Céline J Bossard, Carine Saunier, Imre Fejes, Alain Bruno, John A Hickman

Mol Cancer Ther· September 2013

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N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.
Dimitry Ofengeim, Ying-Bei Chen, Takahiro Miyawaki, Hongmei Li, Silvio Sacchetti, John A Hickman

Nat Neurosci· February 2012

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Only a subset of Met-activated pathways are required to sustain oncogene addiction.
Andrea Bertotti, Mike F Burbridge, Stefania Gastaldi, Francesco Galimi, Davide Torti, John A Hickman

Sci Signal· March 2011

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Mitochondrial fragmentation and neuronal cell death in response to the Bcl-2/Bcl-x(L)/Bcl-w antagonist ABT-737.
Kenneth W Young, Lucia G P Piñón, Dalbir Dhiraj, Davina Twiddy, Marion Macfarlane, John Hickman

Neuropharmacology· June 2010

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An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells.
Nathalie Cahuzac, Aurélie Studény, Kris Marshall, Isabella Versteege, Kate Wetenhall, John A Hickman

Cancer Lett· March 2010

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Only a subset of Met-activated pathways are required to sustain oncogene addiction.
Andrea Bertotti, Mike F Burbridge, Stefania Gastaldi, Francesco Galimi, Davide Torti, John A Hickman

Sci Signal· December 2009

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Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.
Tristan Gallenne, Fabien Gautier, Lisa Oliver, Eric Hervouet, Belinda Noël, John A Hickman

J Cell Biol· April 2009

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