Publications by authors named "Marcus Fancher"

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Design, Synthesis, and T Cell Checkpoint Combination Potential Of First-In-Class DGKα/ζ Inhibitor BMS-986408.
Denise C Grünenfelder, Upender Velaparthi, Jayakumar S Warrier, Louis Chupak, Chetan Padmakar Darne, R Marcus Fancher

J Med Chem· October 2025

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Evaluation of Encequidar as An Intestinal P-gp and BCRP Specific Inhibitor to Assess the Role of Intestinal P-gp and BCRP in Drug-Drug Interactions.
Jessica Chu, Erika Panfen, Linna Wang, Anthony Marino, Xue-Qing Chen, R Marcus Fancher

Pharm Res· November 2023

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Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo.
Yueping Zhang, Petia A Shipkova, Bethanne M Warrack, David M Nelson, Linna Wang, R Marcus Fancher

Drug Metab Dispos· July 2023

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Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits.
Charles Mattis, Natalie Bratcher, Monika Burns, Christopher Carosino, Christina de Zafra, R Marcus Fancher

Int J Toxicol· August 2022

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Absence of OATP1B (Organic Anion-Transporting Polypeptide) Induction by Rifampin in Cynomolgus Monkeys: Determination Using the Endogenous OATP1B Marker Coproporphyrin and Tissue Gene Expression.
Yueping Zhang, Cliff Chen, Shen-Jue Chen, Xue-Qing Chen, David J Shuster, R Marcus Fancher

J Pharmacol Exp Ther· October 2020

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Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.
Xiaomei Gu, Lifei Wang, Jinping Gan, R Marcus Fancher, Yuan Tian

Drug Metab Dispos· August 2020

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Dissecting the Contribution of OATP1B1 to Hepatic Uptake of Statins Using the OATP1B1 Selective Inhibitor Estropipate.
Yueping Zhang, Erika Panfen, Marcus Fancher, Michael Sinz, Punit Marathe

Mol Pharm· June 2019

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A convenient strategy to overcome interference in LC-MS/MS analysis: Application in a microdose absolute bioavailability study.
Long Yuan, Christine Huang, Peggy Liu-Kreyche, Kimberly Voronin, R Marcus Fancher

J Pharm Biomed Anal· February 2019

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Investigation of the "true" extraction recovery of analytes from multiple types of tissues and its impact on tissue bioanalysis using two model compounds.
Long Yuan, Li Ma, Lisa Dillon, R Marcus Fancher, Huadong Sun

Anal Chim Acta· November 2016

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Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement.
Wenying Li, Weiping Zhao, Xiaohong Liu, Xiaohua Huang, Omar D Lopez, R Marcus Fancher

Drug Metab Dispos· June 2016

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Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.
Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, R Marcus Fancher

Drug Metab Dispos· February 2016

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Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.
Hong Shen, Hong Su, Tongtong Liu, Ming Yao, Gabe Mintier, R Marcus Fancher

J Pharmacol Exp Ther· May 2015

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Utility of in situ sodium alginate/karaya gum gels to facilitate gastric retention in rodents.
Kimberly A Foster, Mike Morgen, Brice Murri, Ian Yates, R Marcus Fancher

Int J Pharm· September 2012

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Development of a canine model to enable the preclinical assessment of pH-dependent absorption of test compounds.
R Marcus Fancher, Hongjian Zhang, Bogdan Sleczka, George Derbin, Richard Rockar

J Pharm Sci· July 2011

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