Publications by authors named "Markus Welcker"

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Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.
Markus Welcker, Baiyun Wang, Domniţa-Valeria Rusnac, Yasser Hussaini, Jherek Swanger

Sci Adv· January 2022

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Merkel cell polyomavirus Tumor antigens expressed in Merkel cell carcinoma function independently of the ubiquitin ligases Fbw7 and β-TrCP.
Kristine N Dye, Markus Welcker, Bruce E Clurman, Ann Roman, Denise A Galloway

PLoS Pathog· January 2019

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Oncoprotein ubiquitylation: dimers, degrons, and degradation.
Markus Welcker, Bruce E Clurman

Cell Cycle· January 2015

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Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.
Ryan J Davis, Markus Welcker, Bruce E Clurman

Cancer Cell· October 2014

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Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Markus Welcker, Elizabeth A Larimore, Jherek Swanger, Maria T Bengoechea-Alonso, Jonathan E Grim

Genes Dev· December 2013

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Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase.
Asli A Hizli, Yong Chi, Jherek Swanger, John H Carter, Yi Liao, Markus Welcker

Mol Cell Biol· February 2013

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Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3.
Markus Welcker, Elizabeth A Larimore, Lori Frappier, Bruce E Clurman

Mol Cell Biol· March 2011

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Identification of CDK2 substrates in human cell lysates.
Yong Chi, Markus Welcker, Asli A Hizli, Jeffrey J Posakony, Ruedi Aebersold

Genome Biol· October 2008

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Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma.
Hui Liu, Jing Huang, Jin Wang, Shuguang Jiang, Alexis S Bailey, Markus Welcker

J Exp Med· August 2008

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Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.
Alex C Minella, Keith R Loeb, Andrea Knecht, Markus Welcker, Barbara J Varnum-Finney

Genes Dev· June 2008

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Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
Jonathan E Grim, Michael P Gustafson, Roli K Hirata, Amanda C Hagar, Jherek Swanger, Markus Welcker

J Cell Biol· June 2008

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FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation.
Markus Welcker, Bruce E Clurman

Nat Rev Cancer· February 2008

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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Markus Welcker

J Exp Med· August 2007

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Fbw7/hCDC4 dimerization regulates its substrate interactions.
Markus Welcker, Bruce E Clurman

Cell Div· February 2007

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Kinase-independent function of cyclin E.
Yan Geng, Young-Mi Lee, Markus Welcker, Jherek Swanger, Agnieszka Zagozdzon

Mol Cell· January 2007

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Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins.
Michael P Gustafson, Markus Welcker, Harry C Hwang, Bruce E Clurman

Biochem Biophys Res Commun· December 2005

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Cell cycle: how cyclin E got its groove back.
Markus Welcker, Bruce Clurman

Curr Biol· October 2005

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Ras activity regulates cyclin E degradation by the Fbw7 pathway.
Alex C Minella, Markus Welcker, Bruce E Clurman

Proc Natl Acad Sci U S A· July 2005

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The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.
Markus Welcker, Bruce E Clurman

J Biol Chem· March 2005

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Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase.
Xin Ye, Grzegorz Nalepa, Markus Welcker, Benedikt M Kessler, Eric Spooner

J Biol Chem· November 2004

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A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
Markus Welcker, Amir Orian, Jonathan E Grim, Robert N Eisenman, Bruce E Clurman

Curr Biol· October 2004

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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
Markus Welcker, Amir Orian, Jianping Jin, Jonathan E Grim, J Wade Harper

Proc Natl Acad Sci U S A· June 2004

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Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.
Markus Welcker, Jeffrey Singer, Keith R Loeb, Jonathan Grim, Andrew Bloecher

Mol Cell· August 2003

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p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation.
Alex C Minella, Jherek Swanger, Eileen Bryant, Markus Welcker, Harry Hwang

Curr Biol· October 2002

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