Publications by authors named "Melissa Pink"

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The phosphoinositide-3 kinase (PI3K)-δ,γ inhibitor, duvelisib shows preclinical synergy with multiple targeted therapies in hematologic malignancies.
Kerrie Faia, Kerry White, Erin Murphy, Jennifer Proctor, Melissa Pink

PLoS One· January 2019

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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss, Melissa Pink

Cell Rep· February 2018

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Corrigendum: PI3Kγ is a molecular switch that controls immune suppression.
Megan M Kaneda, Karen S Messer, Natacha Ralainirina, Hongying Li, Christopher J Leem, Melissa Pink

Nature· February 2017

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PI3Kγ is a molecular switch that controls immune suppression.
Megan M Kaneda, Karen S Messer, Natacha Ralainirina, Hongying Li, Christopher J Leem, Melissa Pink

Nature· November 2016

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Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.
Olivier De Henau, Matthew Rausch, David Winkler, Luis Felipe Campesato, Cailian Liu, Melissa Pink

Nature· November 2016

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Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate.
Catherine A Evans, Tao Liu, André Lescarbeau, Somarajan J Nair, Louis Grenier, Melissa M Pink

ACS Med Chem Lett· September 2016

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PI3K-δ and PI3K-γ inhibition by IPI-145 abrogates immune responses and suppresses activity in autoimmune and inflammatory disease models.
David G Winkler, Kerrie L Faia, Jonathan P DiNitto, Janid A Ali, Kerry F White, Melissa M Pink

Chem Biol· November 2013

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The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo.
Mark Douglas, Alice R Lim, James R Porter, Kip West, Melissa M Pink

Mol Cancer Ther· December 2009

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Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).
Martin R Tremblay, André Lescarbeau, Michael J Grogan, Eddy Tan, Grace Lin, Melissa Pink

J Med Chem· July 2009

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Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.
Jens R Sydor, Emmanuel Normant, Christine S Pien, James R Porter, Jie Ge, Melissa Pink

Proc Natl Acad Sci U S A· November 2006

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