Publications by authors named "Melvin Andersen"

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Haloacetamides exacerbate non-alcoholic fatty liver disease induced by a high-fat diet in C57BL/6J mice.
Zhiqiang Jiang, Lili Yang, Qinxin Liu, Meiyue Qiu, Yu Chen, Melvin Andersen

Toxicol Sci· March 2025

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Subchronic Exposure to Low-Level Lanthanum, Cerium, and Yttrium Mixtures Altered Cell Cycle and Increased Oxidative Stress Pathways in Human LO-2 Hepatocytes but Did Not Cause Malignant Transformation.
Qinxin Liu, Zhiqiang Jiang, Meiyue Qiu, Melvin E Andersen, M James C Crabbe

Environ Sci Technol· December 2024

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Haloacetamides disinfection by-products, a potential risk factor for nonalcoholic fatty liver disease.
Zhiqiang Jiang, Lili Yang, Qinxin Liu, Meiyue Qiu, Yu Chen, Melvin E Andersen

Water Res· September 2024

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Transcriptomic re-analyses of human hepatocyte spheroids treated with PFAS reveals chain length and dose-dependent modes of action.
A Rasim Barutcu, Michael B Black, Melvin E Andersen

Toxicol Appl Pharmacol· August 2024

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Disinfection Byproducts of Haloacetaldehydes Disrupt Hepatic Lipid Metabolism and Induce Lipotoxicity in High-Fat Culture Conditions.
Lili Yang, Zhiqiang Jiang, Lan Yang, Weiwei Zheng, Yu Chen, Melvin E Andersen

Environ Sci Technol· July 2024

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Transcriptomic analysis of AHR wildtype and Knock-out rat livers supports TCDD's role in AHR/ARNT-mediated circadian disruption and hepatotoxicity.
Melvin E Andersen, A Rasim Barutcu, Michael B Black, Joshua A Harrill

Toxicol Appl Pharmacol· June 2024

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Use of quantitative to extrapolation (QIVIVE) for the assessment of non-combustible next-generation product aerosols.
Marjory Moreau, Liam Simms, Melvin E Andersen, Edgar Trelles Sticken, Roman Wieczorek

Front Toxicol· April 2024

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Interpretable predictive models of genome-wide aryl hydrocarbon receptor-DNA binding reveal tissue-specific binding determinants.
David Filipovic, Wenjie Qi, Omar Kana, Daniel Marri, Edward L LeCluyse, Melvin E Andersen

Toxicol Sci· November 2023

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Updating the biologically based dose-response model for the nasal carcinogenicity of inhaled formaldehyde in the F344 rat.
Rory B Conolly, Jeffry Schroeter, Julia S Kimbell, Harvey Clewell, Melvin E Andersen

Toxicol Sci· May 2023

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Incorporation of rapid association/dissociation processes in tissues into the monkey and human physiologically based pharmacokinetic models for manganese.
Jerry L Campbell, Harvey J Clewell, Cynthia Van Landingham, P Robinan Gentry, Athena M Keene, Melvin E Andersen

Toxicol Sci· February 2023

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Incorporation of a recirculating mobile lipid pool description into the cyclic volatile siloxane (cVMS) PBPK model captures terminal clearance of D after repeated inhalation exposure in F344 and SD Rats.
Jerry Campbell, Melvin Andersen, Robinan Gentry, Cynthia Van Landingham, Harvey Clewell

Toxicol Lett· February 2023

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Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity.
Amy J Stefanowicz, Leslie Recio, Michael B Black, Tyler Beames, Melvin E Andersen

Int J Toxicol· January 2023

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NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene.
Marjory Moreau, Jeff Fisher, Melvin E Andersen, Asayah Barnwell, Sage Corzine

Toxicology· November 2022

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Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods.
Chantel I Nicolas, Matthew W Linakis, Melyssa S Minto, Kamel Mansouri, Rebecca A Clewell, Melvin E Andersen

Front Pharmacol· October 2022

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NRF2-ARE signaling is responsive to haloacetonitrile-induced oxidative stress in human keratinocytes.
Peng Xue, Huihui Wang, Lili Yang, Zhiqiang Jiang, Hongliang Li, Melvin E Andersen

Toxicol Appl Pharmacol· September 2022

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Single enrichment systems possibly underestimate both exposures and biological effects of organic pollutants from drinking water.
Lan Yang, Ying Zhou, Li Chen, Hanyi Chen, Wenhao Liu, Melvin E Andersen

Chemosphere· April 2022

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The genotoxic potential of mixed nitrosamines in drinking water involves oxidative stress and Nrf2 activation.
Lei Dong, Zhiqiang Jiang, Lili Yang, Fen Hu, Weiwei Zheng, Melvin E Andersen

J Hazard Mater· March 2022

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Assessing modes of action, measures of tissue dose and human relevance of rodent toxicity endpoints with octamethylcyclotetrasiloxane (D4).
Melvin E Andersen

Toxicol Lett· March 2022

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Corrigendum to "Regulatory role of KEAP1 and NRF2 in PPARg expression and chemoresistance in human non-small-cell lung carcinoma cells" [Free Radic Biol Med. 53 (2012) 758-68. doi: 10.1016/j.freeradbiomed.2012.05.041. Epub 2012 Jun 7. PMID: 22684020].
Lijuan Zhan, Hao Zhang, Qiang Zhang, Courtney G Woods, Yanyan Chen, Melvin E Andersen

Free Radic Biol Med· February 2022

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RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days.
Michael B Black, Melvin E Andersen, Salil N Pendse, Susan J Borghoff, Michael Streicker

Data Brief· October 2021

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Time-dependent genomic response in primary human uroepithelial cells exposed to arsenite for up to 60 days.
Alina Efremenko, Pergentino Balbuena, Rebecca A Clewell, Michael Black, Linda Pluta, Melvin E Andersen

Toxicology· September 2021

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A systematic approach to evaluate plausible modes of actions for mouse lung tumors in mice exposed to 4-methylimidozole.
Susan J Borghoff, Seneca E Fitch, Michael B Black, Patrick D McMullen, Melvin E Andersen

Regul Toxicol Pharmacol· August 2021

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Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms.
Melvin E Andersen, Bruno Hagenbuch, Udayan Apte, J Christopher Corton, Tony Fletcher

Toxicology· July 2021

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Using quantitative modeling tools to assess pharmacokinetic bias in epidemiological studies showing associations between biomarkers and health outcomes at low exposures.
Melvin E Andersen, Pankajini Mallick, Harvey J Clewell, Miyoung Yoon, Geary W Olsen

Environ Res· June 2021

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Integration of paraquat pharmacokinetic data across species using PBPK modelling.
Jerry L Campbell, Kim Z Travis, Harvey J Clewell, Alexander J Stevens, Paul M Hinderliter, Melvin E Andersen

Toxicol Appl Pharmacol· April 2021

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